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Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms.

• Authors : Li Q; The Center for Microbes, Development and Health, CAS Key Laboratory of Molecular Virology and Immunology, Shanghai Institute of Immunity and Infection, Chinese Academy of Sciences,University of Chinese Academy of Sciences, Shanghai, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.

Subjects: Cryoelectron Microscopy* ; Saccharomyces cerevisiae Proteins*/Saccharomyces cerevisiae Proteins*/Saccharomyces cerevisiae Proteins*/chemistry ; Saccharomyces cerevisiae Proteins*/Saccharomyces cerevisiae Proteins*/Saccharomyces cerevisiae Proteins*/metabolism

• Source: Nature structural & molecular biology [Nat Struct Mol Biol] 2024 Oct; Vol. 31 (10), pp. 1532-1542. Date of Electronic Publication: 2024 Jun 18.Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101186374 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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The SMC5/6 complex subunit MMS21 regulates stem cell proliferation in rice.

• Authors : Xun, Qian; Song, Ye; Mei, Min

Subjects: CELL proliferation; STEM cell niches; STEM cells

• Source: Plant Cell Reports; Aug2023, Vol. 42 Issue 8, p1279-1290, 12p

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The SMC5/6 complex: folding chromosomes back into shape when genomes take a break.

• Authors : Roy S; Ottawa Institute of Systems Biology, Department of Cellular and Molecular Medicine, University of Ottawa, Roger Guindon Hall, 451 Smyth Rd, Ottawa, ON K1H 8M5, Canada.; Adhikary H

Subjects: Cell Cycle Proteins*/Cell Cycle Proteins*/Cell Cycle Proteins*/metabolism ; Chromosomal Proteins, Non-Histone*/Chromosomal Proteins, Non-Histone*/Chromosomal Proteins, Non-Histone*/metabolism; Humans

• Source: Nucleic acids research [Nucleic Acids Res] 2024 Mar 21; Vol. 52 (5), pp. 2112-2129.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

• Authors : Oravcová, Martina; Minghua Nie; Zilio, Nicola

• Source: eLife; 11/29/2022, p1-37, 37p

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Molecular basis for Nse5-6 mediated regulation of Smc5/6 functions.

• Authors : Li S; Molecular Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065.; Yu Y

Subjects: Chromosomal Proteins, Non-Histone*/Chromosomal Proteins, Non-Histone*/Chromosomal Proteins, Non-Histone*/metabolism ; DNA Repair*; DNA Replication

• Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Nov 07; Vol. 120 (45), pp. e2310924120. Date of Electronic Publication: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Caenorhabditis elegans NSE3 homolog (MAGE-1) is involved in genome stability and acts in inter-sister recombination during meiosis.

• Authors : Odiba AS; State Key Laboratory of Non-food Biomass and Enzyme Technology, Guangxi Academy of Sciences, Nanning 530007, China.; State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.

Subjects: Caenorhabditis elegans Proteins*/Caenorhabditis elegans Proteins*/Caenorhabditis elegans Proteins*/genetics ; Caenorhabditis elegans Proteins*/Caenorhabditis elegans Proteins*/Caenorhabditis elegans Proteins*/metabolism ; Genomic Instability*

• Source: Genetics [Genetics] 2023 Oct 04; Vol. 225 (2).Publisher: Oxford University Press Country of Publication: United States NLM ID: 0374636 Publication Model: Print Cited Medium: Internet ISSN:

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The multi-functional Smc5/6 complex in genome protection and disease.

• Authors : Peng XP; Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Zhao X

Subjects: DNA Replication* ; DNA*; Animals

• Source: Nature structural & molecular biology [Nat Struct Mol Biol] 2023 Jun; Vol. 30 (6), pp. 724-734. Date of Electronic Publication: 2023 Jun 19.Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101186374 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Loss of NSE-4 Perturbs Genome Stability and DNA Repair in Caenorhabditis elegans .

• Authors : Odiba AS; State Key Laboratory of Non-Food Biomass and Enzyme Technology, Guangxi Academy of Sciences, Nanning 530007, China.; State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.

Subjects: Caenorhabditis elegans*/Caenorhabditis elegans*/Caenorhabditis elegans*/genetics ; Caenorhabditis elegans*/Caenorhabditis elegans*/Caenorhabditis elegans*/metabolism ; Cell Cycle Proteins*/Cell Cycle Proteins*/Cell Cycle Proteins*/metabolism

• Source: International journal of molecular sciences [Int J Mol Sci] 2022 Jun 29; Vol. 23 (13). Date of Electronic Publication: 2022 Jun 29.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Smc5/6 Complex Promotes Rad3 ATR Checkpoint Signaling at the Perturbed Replication Fork through Sumoylation of the RecQ Helicase Rqh1.

• Authors : Khan S; Department of Pharmacology and Toxicology, Boonshoft School of Medicine, Wright State Universitygrid.268333.f, Dayton, Ohio, USA.; Ahamad N

Subjects: Schizosaccharomyces*/Schizosaccharomyces*/Schizosaccharomyces*/genetics ; Schizosaccharomyces*/Schizosaccharomyces*/Schizosaccharomyces*/metabolism ; Schizosaccharomyces pombe Proteins*/Schizosaccharomyces pombe Proteins*/Schizosaccharomyces pombe Proteins*/genetics

• Source: Molecular and cellular biology [Mol Cell Biol] 2022 Jun 16; Vol. 42 (6), pp. e0004522. Date of Electronic Publication: 2022 May 25.Publisher: Taylor & Francis Country of Publication: United States NLM ID: 8109087 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Multiple Roles of SMC5/6 Complex during Plant Sexual Reproduction.

• Authors : Yang F; Centre of the Region Haná for Biotechnological and Agricultural Research (CRH), Institute of Experimental Botany (IEB), Czech Academy of Sciences, 77900 Olomouc, Czech Republic.; Department of Cell Biology and Genetics, Faculty of Science, Palacký University, 77900 Olomouc, Czech Republic.

Subjects: Arabidopsis*/Arabidopsis*/Arabidopsis*/genetics ; Arabidopsis*/Arabidopsis*/Arabidopsis*/metabolism ; Cell Cycle Proteins*/Cell Cycle Proteins*/Cell Cycle Proteins*/genetics

• Source: International journal of molecular sciences [Int J Mol Sci] 2022 Apr 19; Vol. 23 (9). Date of Electronic Publication: 2022 Apr 19.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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