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A GDP dissociation inhibitor that serves as a GTPase inhibitor for the Ras-like protein CDC42Hs.

• Authors : Hart, Matthew J.; Maru, Yoshiro; Leonard, David

• Source: Science. October 30, 1992, Vol. 258 Issue 5083, p812, 4 p.

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SmgGDS stabilizes nucleotide-bound and -free forms of the Rac1 GTP-binding protein and stimulates GTP/GDP exchange through a substituted enzyme mechanism.

• Authors : Chuang TH; Department of Immunology, Scripps Research Institute, La Jolla, CA 92037.; Xu X

Subjects: GTP-Binding Proteins/GTP-Binding Proteins/GTP-Binding Proteins/*metabolism ; Guanosine Diphosphate/Guanosine Diphosphate/Guanosine Diphosphate/*metabolism ; Guanosine Triphosphate/Guanosine Triphosphate/Guanosine Triphosphate/*metabolism

• Source: The Biochemical journal [Biochem J] 1994 Nov 01; Vol. 303 ( Pt 3), pp. 761-7.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited

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Differential expression of distinct members of Rho family GTP-binding proteins during neuronal development: identification of Rac1B, a new neural-specific member of the family.

• Authors : Malosio ML; Cell Adhesion Unit, Department of Biological and Technological Research (DIBIT), San Raffaele Scientific Institute, 20132 Milano, Italy.; Gilardelli D

Subjects: rac GTP-Binding Proteins*; GTP-Binding Proteins/GTP-Binding Proteins/GTP-Binding Proteins/*metabolism ; Nerve Tissue Proteins/Nerve Tissue Proteins/Nerve Tissue Proteins/*metabolism

• Source: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 1997 Sep 01; Vol. 17 (17), pp. 6717-28.Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Print Cited Medium: Print ISSN:

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GEF-mediated GDP/GTP exchange by monomeric GTPases: A regulatory role for Mg2+?

• Authors : Pan, Julie Y.; Wessling-Resnick, Marianne

Subjects: GUANOSINE triphosphatase; G proteins

• Source: BioEssays; Jun98, Vol. 20 Issue 6, p516, 6p, 3 Diagrams

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Overexpression of a neural-specific rho family GTPase, cRac1B, selectively induces enhanced neuritogenesis and neurite branching in primary neurons.

• Authors : Albertinazzi C; Cell Adhesion Unit, Department of Biological and Technological Research, San Raffaele Scientific Institute, 20132 Milano, Italy.; Gilardelli D

Subjects: rac GTP-Binding Proteins*; GTP Phosphohydrolases/GTP Phosphohydrolases/GTP Phosphohydrolases/*physiology ; GTP-Binding Proteins/GTP-Binding Proteins/GTP-Binding Proteins/*physiology

• Source: The Journal of cell biology [J Cell Biol] 1998 Aug 10; Vol. 142 (3), pp. 815-25.Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 0375356 Publication Model: Print Cited Medium: Print ISSN:

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Lipid kinases are novel effectors of the GTPase Rac1.

• Authors : Carpenter CL; Harvard Medical School, Boston, MA 02215, USA.; Tolias KF

Subjects: Lipid Metabolism*; GTP Phosphohydrolases/GTP Phosphohydrolases/GTP Phosphohydrolases/*metabolism ; Phosphotransferases/Phosphotransferases/Phosphotransferases/*metabolism

• Source: Advances in enzyme regulation [Adv Enzyme Regul] 1999; Vol. 39, pp. 299-312.Publisher: Pergamon Press Country of Publication: England NLM ID: 0044263 Publication Model: Print Cited Medium: Print ISSN: 0065-2571 (Print)

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The actin cytoskeleton reorganization induced by Rac1 requires the production of superoxide.

• Authors : Moldovan L; Heart and Lung Institute, Department of Internal Medicine, The Ohio State University, Columbus 43210, USA.; Irani K

Subjects: Actins/Actins/Actins/*metabolism ; Cytoskeleton/Cytoskeleton/Cytoskeleton/*metabolism ; Endothelium, Vascular/Endothelium, Vascular/Endothelium, Vascular/*metabolism

• Source: Antioxidants & redox signaling [Antioxid Redox Signal] 1999 Spring; Vol. 1 (1), pp. 29-43.Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 100888899 Publication Model: Print Cited Medium: Print ISSN:

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Microtubule growth activates Rac1 to promote lamellipodial protrusion in fibroblasts.

• Authors : Waterman-Storer CM; Department of Biology, University of North Carolina, Chapel Hill 27599, USA. ; Worthylake RA

Subjects: Microtubules/Microtubules/Microtubules/*physiology ; rac1 GTP-Binding Protein/rac1 GTP-Binding Protein/rac1 GTP-Binding Protein/*metabolism; 3T3 Cells/3T3 Cells/3T3 Cells/drug effects

• Source: Nature cell biology [Nat Cell Biol] 1999 May; Vol. 1 (1), pp. 45-50.Publisher: Macmillan Magazines Ltd Country of Publication: England NLM ID: 100890575 Publication Model: Print Cited Medium: Print ISSN: 1465-7392

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Sema3A-induced growth-cone collapse is mediated by Rac1 amino acids 17-32.

• Authors : Västrik I; Molecular Neurobiology Group GKT School of Medicine King's College London London, SE1 9RT, Computational Genome Analysis Laboratory ICRF 44 Lincoln's Inn Fields, London, WC2A 3PX, UK.; Eickholt BJ

Subjects: GTPase-Activating Proteins*; Glycoproteins/Glycoproteins/Glycoproteins/*physiology ; Growth Cones/Growth Cones/Growth Cones/*ultrastructure

• Source: Current biology : CB [Curr Biol] 1999 Sep 23; Vol. 9 (18), pp. 991-8.Publisher: Cell Press Country of Publication: England NLM ID: 9107782 Publication Model: Print Cited Medium: Print ISSN: 0960-9822 (Print)

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Distinct effects of Rac1 on differentiation of primary avian myoblasts.

• Authors : Gallo R; Istituto di Biologia Cellulare, Consiglio Nazionale delle Richerche, 00137 Rome, Italy.; Serafini M

Subjects: rac1 GTP-Binding Protein/rac1 GTP-Binding Protein/rac1 GTP-Binding Protein/*biosynthesis; Animals ; Cell Differentiation

• Source: Molecular biology of the cell [Mol Biol Cell] 1999 Oct; Vol. 10 (10), pp. 3137-50.Publisher: American Society for Cell Biology Country of Publication: United States NLM ID: 9201390 Publication Model: Print Cited Medium: Print ISSN:

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