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Academic Journal

Cell therapy for a rare disease- hairy cell leukemia variant.

  • Authors : Fritz C; Department of Pathology, Case Western Reserve University, Cleveland, OH, USA.; Wong DP

Subjects: Leukemia, Hairy Cell*/Leukemia, Hairy Cell*/Leukemia, Hairy Cell*/therapy ; Leukemia, Hairy Cell*/Leukemia, Hairy Cell*/Leukemia, Hairy Cell*/pathology ; Xenograft Model Antitumor Assays*

  • Source: Oncoimmunology [Oncoimmunology] 2024 Dec 31; Vol. 13 (1), pp. 2432062. Date of Electronic Publication: 2024 Nov 27.Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101570526 Publication Model: Print-Electronic Cited

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Academic Journal

Auranofin inhibition of thioredoxin reductase sensitizes lung neuroendocrine tumor cells (NETs) and small cell lung cancer (SCLC) cells to sorafenib as well as inhibiting SCLC xenograft growth.

  • Authors : Johnson SS; Department of Radiation Oncology, Holden Comprehensive Cancer Center, Free Radical and Radiation Biology Program, University of Iowa Hospitals and Clinics, IA, USA.; Liu D

Subjects: Auranofin*/Auranofin*/Auranofin*/pharmacology ; Auranofin*/Auranofin*/Auranofin*/therapeutic use ; Sorafenib*/Sorafenib*/Sorafenib*/pharmacology

  • Source: Cancer biology & therapy [Cancer Biol Ther] 2024 Dec 31; Vol. 25 (1), pp. 2382524. Date of Electronic Publication: 2024 Jul 25.Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101137842 Publication Model: Print-Electronic Cited

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Academic Journal

Mobocertinib antagonizes multidrug resistance in ABCB1- and ABCG2-overexpressing cancer cells: In vitro and in vivo studies.

  • Authors : Dong XD; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY, 11439, USA.; Zhang M

Subjects: ATP Binding Cassette Transporter, Subfamily G, Member 2*/ATP Binding Cassette Transporter, Subfamily G, Member 2*/ATP Binding Cassette Transporter, Subfamily G, Member 2*/genetics ; ATP Binding Cassette Transporter, Subfamily G, Member 2*/ATP Binding Cassette Transporter, Subfamily G, Member 2*/ATP Binding Cassette Transporter, Subfamily G, Member 2*/metabolism ; Drug Resistance, Neoplasm*/Drug Resistance, Neoplasm*/Drug Resistance, Neoplasm*/drug effects

  • Source: Cancer letters [Cancer Lett] 2024 Dec 28; Vol. 607, pp. 217309. Date of Electronic Publication: 2024 Oct 29.Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited

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Academic Journal

Preclinical evaluation of 89 Zr/ 177 Lu-labeled amatuximab for theranostic application in pancreatic ductal adenocarcinoma.

  • Authors : Lu Z; NHC Key Laboratory of Nuclear Technology Medical Transformation, Mianyang Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Mianyang 621000, China.; Shi M

Subjects: Zirconium*/Zirconium*/Zirconium*/chemistry ; Radioisotopes*/Radioisotopes*/Radioisotopes*/administration & dosage ; Radioisotopes*/Radioisotopes*/Radioisotopes*/chemistry

  • Source: International journal of pharmaceutics [Int J Pharm] 2024 Dec 25; Vol. 667 (Pt B), pp. 124946. Date of Electronic Publication: 2024 Nov 13.Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model:

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Academic Journal

Low-dose treatment with Epirubicin, a novel histone deacetylase 1 inhibitor, exerts anti-leukemic effects by inducing ferroptosis.

  • Authors : Yang G; State Key Laboratory of Trauma and Chemical Poisoning, Medical Center of Hematology, Military Key Clinical Specialty, Chongqing Key Clinical Specialty, Chongqing Key Laboratory of Hematology and Microenvironment, Second Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing, 400037, China; Department of Hematology, Affiliated Hospital of North Sichuan Medical College, Nanchong, 637002, China.

Subjects: Ferroptosis*/Ferroptosis*/Ferroptosis*/drug effects ; Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/pharmacology ; Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/therapeutic use

  • Source: European journal of pharmacology [Eur J Pharmacol] 2024 Dec 15; Vol. 985, pp. 177058. Date of Electronic Publication: 2024 Oct 14.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited

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Academic Journal

Chimeric antigen receptor macrophages targeting c-MET(CAR-M-c-MET) inhibit pancreatic cancer progression and improve cytotoxic chemotherapeutic efficacy.

  • Authors : Zheng H; Department of General Surgery, State Key Laboratory of Complex Severe and Rare Diseases, Dongcheng District, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, No.1 Shuai Fu Yuan, Beijing, 100730, China.; Yang X

Subjects: Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/therapy ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/pathology ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/immunology

  • Source: Molecular cancer [Mol Cancer] 2024 Dec 06; Vol. 23 (1), pp. 270. Date of Electronic Publication: 2024 Dec 06.Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium:

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Academic Journal

CDK9 recruits HUWE1 to degrade RARα and offers therapeutic opportunities for cutaneous T-cell lymphoma.

  • Authors : Luo CH; Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Institute of Dermatology, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Subjects: Cyclin-Dependent Kinase 9*/Cyclin-Dependent Kinase 9*/Cyclin-Dependent Kinase 9*/metabolism ; Cyclin-Dependent Kinase 9*/Cyclin-Dependent Kinase 9*/Cyclin-Dependent Kinase 9*/antagonists & inhibitors ; Lymphoma, T-Cell, Cutaneous*/Lymphoma, T-Cell, Cutaneous*/Lymphoma, T-Cell, Cutaneous*/metabolism

  • Source: Nature communications [Nat Commun] 2024 Dec 05; Vol. 15 (1), pp. 10594. Date of Electronic Publication: 2024 Dec 05.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium:

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Academic Journal

Pterostilbene suppresses the growth of esophageal squamous cell carcinoma by inhibiting glycolysis and PKM2/STAT3/c-MYC signaling pathway.

  • Authors : Yang Y; Medical College, Henan University of Chinese Medicine, Zhengzhou 450046 China; Henan Engineering Research Center for Chinese Medicine Foods for Special Medical Purpose, Zhengzhou 450046 China.

Subjects: STAT3 Transcription Factor*/STAT3 Transcription Factor*/STAT3 Transcription Factor*/metabolism ; Esophageal Squamous Cell Carcinoma*/Esophageal Squamous Cell Carcinoma*/Esophageal Squamous Cell Carcinoma*/drug therapy ; Esophageal Squamous Cell Carcinoma*/Esophageal Squamous Cell Carcinoma*/Esophageal Squamous Cell Carcinoma*/pathology

  • Source: International immunopharmacology [Int Immunopharmacol] 2024 Dec 05; Vol. 142 (Pt B), pp. 113247. Date of Electronic Publication: 2024 Sep 25.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited

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Academic Journal

Tenovin-6 exhibits inhibitory effects on the growth of Sonic Hedgehog (SHH) medulloblastoma, as evidenced by both in vitro and in vivo studies.

  • Authors : Wang B; Department of Neurosurgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang, China.; Xu T

Subjects: Medulloblastoma*/Medulloblastoma*/Medulloblastoma*/drug therapy ; Medulloblastoma*/Medulloblastoma*/Medulloblastoma*/pathology ; Medulloblastoma*/Medulloblastoma*/Medulloblastoma*/metabolism

  • Source: International immunopharmacology [Int Immunopharmacol] 2024 Dec 05; Vol. 142 (Pt A), pp. 113075. Date of Electronic Publication: 2024 Sep 12.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited

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Academic Journal

Engineered extracellular vesicles for combinatorial TNBC therapy: SR-SIM-guided design achieves substantial drug dosage reduction.

  • Authors : Bhullar AS; Center for RNA Nanobiotechnology and Nanomedicine, College of Pharmacy and Comprehensive Cancer Center. The Ohio State University, Columbus, OH 43210, USA; Interdisciplinary Biophysics Graduate Program, The Ohio State University, Columbus, OH 43210, USA.

Subjects: Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/drug therapy ; Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/pathology ; Extracellular Vesicles*/Extracellular Vesicles*/Extracellular Vesicles*/metabolism

  • Source: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2024 Dec 04; Vol. 32 (12), pp. 4467-4481. Date of Electronic Publication: 2024 Oct 05.Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited

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  • 1-10 of  47,936 results for ""Xenograft Model Antitumor Assays""