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Academic Journal

Wiskott-Aldrich syndrome protein maintains regulatory T cell tolerance by modulating their surface IL-2 receptor levels.

  • Authors : Zhao Q; National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Children's Hospital of Chongqing Medical University, Chongqing, China; Chongqing Key Laboratory of Child Rare Diseases in Infection and Immunity, Children's Hospital of Chongqing Medical University, Chongqing, China.

Subjects: T-Lymphocytes, Regulatory*/T-Lymphocytes, Regulatory*/T-Lymphocytes, Regulatory*/immunology ; T-Lymphocytes, Regulatory*/T-Lymphocytes, Regulatory*/T-Lymphocytes, Regulatory*/metabolism ; Wiskott-Aldrich Syndrome Protein*/Wiskott-Aldrich Syndrome Protein*/Wiskott-Aldrich Syndrome Protein*/metabolism

  • Source: Journal of autoimmunity [J Autoimmun] 2024 Dec; Vol. 149, pp. 103336. Date of Electronic Publication: 2024 Nov 16.Publisher: Academic Press Country of Publication: England NLM ID: 8812164 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

A first-in-class Wiskott-Aldrich syndrome protein activator with antitumor activity in hematologic cancers.

  • Authors : Spriano F; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona.; Sartori G

Subjects: Wiskott-Aldrich Syndrome Protein*/Wiskott-Aldrich Syndrome Protein*/Wiskott-Aldrich Syndrome Protein*/metabolism ; Wiskott-Aldrich Syndrome Protein*/Wiskott-Aldrich Syndrome Protein*/Wiskott-Aldrich Syndrome Protein*/genetics ; Hematologic Neoplasms*/Hematologic Neoplasms*/Hematologic Neoplasms*/drug therapy

  • Source: Haematologica [Haematologica] 2024 Nov 01; Vol. 109 (11), pp. 3602-3614. Date of Electronic Publication: 2024 Nov 01.Publisher: Ferrata Storti Foundation Country of Publication: Italy NLM ID: 0417435 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Pan-Cancer Proteomics Analysis Reveals Wiskott-Aldrich Syndrome Protein as a Potential Regulator of Programmed Death-Ligand 1.

  • Authors : Hu L; MOE Key Laboratory of Tumor Molecular Biology and State Key Laboratory of Bioactive Molecules and Druggability Assessment, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.; Liu D

Subjects: B7-H1 Antigen*/B7-H1 Antigen*/B7-H1 Antigen*/metabolism ; B7-H1 Antigen*/B7-H1 Antigen*/B7-H1 Antigen*/genetics ; Proteomics*/Proteomics*/Proteomics*/methods

  • Source: Journal of proteome research [J Proteome Res] 2024 Jun 07; Vol. 23 (6), pp. 2195-2205. Date of Electronic Publication: 2024 Apr 25.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101128775 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Wiskott Aldrich syndrome protein (WASp)-deficient Th1 cells promote R-loop-driven transcriptional insufficiency and transcription-coupled nucleotide excision repair factor (TC-NER)-driven genome-instability in the pathogenesis of T cell acute lymphoblastic leukemia.

  • Authors : R P; Department of Biotechnology, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu 603203, India.; Rakshit S

Subjects: Excision Repair* ; Genomic Instability*/Genomic Instability*/Genomic Instability*/genetics ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma*/Precursor T-Cell Lymphoblastic Leukemia-Lymphoma*/Precursor T-Cell Lymphoblastic Leukemia-Lymphoma*/genetics

  • Source: Clinical immunology (Orlando, Fla.) [Clin Immunol] 2024 Jun; Vol. 263, pp. 110204. Date of Electronic Publication: 2024 Apr 04.Publisher: Academic Press Country of Publication: United States NLM ID: 100883537 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Mutational Landscape of Patients with Wiskott Aldrich Syndrome: Update from India.

  • Authors : Gaikwad P; Indian Council of Medical Research (ICMR)-National Institute of Immunohaematology (NIIH), Parel, Mumbai, India.; Bargir UA

Subjects: Wiskott-Aldrich Syndrome*/Wiskott-Aldrich Syndrome*/Wiskott-Aldrich Syndrome*/genetics ; Wiskott-Aldrich Syndrome*/Wiskott-Aldrich Syndrome*/Wiskott-Aldrich Syndrome*/diagnosis ; Wiskott-Aldrich Syndrome*/Wiskott-Aldrich Syndrome*/Wiskott-Aldrich Syndrome*/immunology

  • Source: Journal of clinical immunology [J Clin Immunol] 2024 Dec 17; Vol. 45 (1), pp. 56. Date of Electronic Publication: 2024 Dec 17.Publisher: Springer Country of Publication: Netherlands NLM ID: 8102137 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-2592

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Academic Journal

Association of Wiskott-Aldrich syndrome protein (WASp) in epigenetic regulation of B cell differentiation in non-small-cell lung cancer (NSCLC).

  • Authors : Chandnani N; Department of Biotechnology, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu, 603203, India.; Mandal A

Subjects: Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/genetics ; Lung Neoplasms*/Lung Neoplasms*/Lung Neoplasms*/genetics ; Wiskott-Aldrich Syndrome Protein*/Wiskott-Aldrich Syndrome Protein*/Wiskott-Aldrich Syndrome Protein*/genetics

  • Source: Medical oncology (Northwood, London, England) [Med Oncol] 2023 Dec 25; Vol. 41 (1), pp. 28. Date of Electronic Publication: 2023 Dec 25.Publisher: Springer Country of Publication: United States NLM ID: 9435512 Publication Model: Electronic Cited Medium: Internet ISSN: 1559-131X

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Academic Journal

Controlled WASp activity regulates the proliferative response for Treg cell differentiation in the thymus.

  • Authors : Vasconcelos-Fontes L; Department of Microbiology Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.; Laboratory on Thymus Research, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil.

Subjects: T-Lymphocytes, Regulatory*/T-Lymphocytes, Regulatory*/T-Lymphocytes, Regulatory*/immunology ; Cell Differentiation*/Cell Differentiation*/Cell Differentiation*/immunology ; Wiskott-Aldrich Syndrome Protein*/Wiskott-Aldrich Syndrome Protein*/Wiskott-Aldrich Syndrome Protein*/genetics

  • Source: European journal of immunology [Eur J Immunol] 2024 May; Vol. 54 (5), pp. e2350450. Date of Electronic Publication: 2024 Feb 14.Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 1273201 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-4141

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Academic Journal

The Wiskott-Aldrich syndrome protein is required for positive selection during T-cell lineage differentiation.

  • Authors : Pille M; Laboratory of Experimental Immunology, Department of Diagnostic Sciences, Ghent University, Ghent, Belgium.; Avila J

Subjects: Wiskott-Aldrich Syndrome Protein*/Wiskott-Aldrich Syndrome Protein*/Wiskott-Aldrich Syndrome Protein*/metabolism ; Wiskott-Aldrich Syndrome*; Humans

  • Source: Frontiers in immunology [Front Immunol] 2023 Jun 07; Vol. 14, pp. 1188099. Date of Electronic Publication: 2023 Jun 07 (Print Publication: 2023).Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Wiskott-Aldrich syndrome protein interacts and inhibits diacylglycerol kinase alpha promoting IL-2 induction.

  • Authors : Velnati S; Department of Translational Medicine, Universitàdel Piemonte Orientale, Novara, Italy.; Center for Translational Research on Allergic and Autoimmune Diseases (CAAD), Università del Piemonte Orientale, Novara, Italy.

Subjects: Diacylglycerol Kinase*/Diacylglycerol Kinase*/Diacylglycerol Kinase*/genetics ; Wiskott-Aldrich Syndrome Protein*; Humans

  • Source: Frontiers in immunology [Front Immunol] 2023 Apr 17; Vol. 14, pp. 1043603. Date of Electronic Publication: 2023 Apr 17 (Print Publication: 2023).Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Why Does Synergistic Activation of WASP, but Not N-WASP, by Cdc42 and PIP 2 Require Cdc42 Prenylation?

  • Authors : Dey S; Department of Chemistry, University of Illinois at Chicago, Chicago, IL 60607, USA. Electronic address: https://twitter.com/SouvikDeyUIC.; Zhou HX

Subjects: cdc42 GTP-Binding Protein*/cdc42 GTP-Binding Protein*/cdc42 GTP-Binding Protein*/chemistry ; cdc42 GTP-Binding Protein*/cdc42 GTP-Binding Protein*/cdc42 GTP-Binding Protein*/metabolism ; Wiskott-Aldrich Syndrome Protein*/Wiskott-Aldrich Syndrome Protein*/Wiskott-Aldrich Syndrome Protein*/chemistry

  • Source: Journal of molecular biology [J Mol Biol] 2023 Apr 15; Vol. 435 (8), pp. 168035. Date of Electronic Publication: 2023 Feb 28.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 2985088R Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  14,917 results for ""Wiskott-Aldrich Syndrome Protein""