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Academic Journal

Tissue spaces are reservoirs of antigenic diversity for Trypanosoma brucei.

  • Authors : Beaver AK; Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, USA.; Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

Subjects: Antigenic Variation*/Antigenic Variation*/Antigenic Variation*/genetics ; Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/genetics ; Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/immunology

  • Source: Nature [Nature] 2024 Dec; Vol. 636 (8042), pp. 430-437. Date of Electronic Publication: 2024 Oct 30.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Protein phosphatase PP1 regulation of RNA polymerase II transcription termination and allelic exclusion of VSG genes in trypanosomes.

  • Authors : Kieft R; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602, USA.; Zhang Y

Subjects: RNA Polymerase II*/RNA Polymerase II*/RNA Polymerase II*/metabolism ; RNA Polymerase II*/RNA Polymerase II*/RNA Polymerase II*/genetics ; Protein Phosphatase 1*/Protein Phosphatase 1*/Protein Phosphatase 1*/genetics

  • Source: Nucleic acids research [Nucleic Acids Res] 2024 Jul 08; Vol. 52 (12), pp. 6866-6885.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Beyond the VSG layer: Exploring the role of intrinsic disorder in the invariant surface glycoproteins of African trypanosomes.

  • Authors : Sülzen H; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Prague, Czech Republic.; Faculty of Science, Charles University, Prague, Czech Republic.

Subjects: Variant Surface Glycoproteins, Trypanosoma*/Variant Surface Glycoproteins, Trypanosoma*/Variant Surface Glycoproteins, Trypanosoma*/metabolism ; Trypanosomiasis, African*/Trypanosomiasis, African*/Trypanosomiasis, African*/parasitology ; Trypanosomiasis, African*/Trypanosomiasis, African*/Trypanosomiasis, African*/immunology

  • Source: PLoS pathogens [PLoS Pathog] 2024 Apr 22; Vol. 20 (4), pp. e1012186. Date of Electronic Publication: 2024 Apr 22 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Poly(m 6 A) tails stabilize transcripts.

  • Authors : Lavergne G; Center for Integrative Genomics, Génopode Building, Faculty of Biology and Medicine, University of Lausanne, CH-1015, Lausanne, Switzerland.; Roignant JY

Subjects: Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/genetics ; Variant Surface Glycoproteins, Trypanosoma*/Variant Surface Glycoproteins, Trypanosoma*/Variant Surface Glycoproteins, Trypanosoma*/genetics; Animals

  • Source: Molecular cell [Mol Cell] 2022 Jun 02; Vol. 82 (11), pp. 1979-1980.Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print Cited Medium: Internet ISSN: 1097-4164

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Academic Journal

N 6 -methyladenosine in poly(A) tails stabilize VSG transcripts.

  • Authors : Viegas IJ; Instituto de Medicina Molecular-João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.; de Macedo JP

Subjects: RNA Processing, Post-Transcriptional* ; Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/genetics ; Variant Surface Glycoproteins, Trypanosoma*/Variant Surface Glycoproteins, Trypanosoma*/Variant Surface Glycoproteins, Trypanosoma*/genetics

  • Source: Nature [Nature] 2022 Apr; Vol. 604 (7905), pp. 362-370. Date of Electronic Publication: 2022 Mar 30.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

An assembly of nuclear bodies associates with the active VSG expression site in African trypanosomes.

  • Authors : Budzak J; Department of Life Sciences, Sir Alexander Fleming Building, Imperial College London, South Kensington, London, SW7 2AZ, UK.; Jones R

Subjects: RNA Splicing* ; Transcription, Genetic*; Nuclear Bodies/Nuclear Bodies/Nuclear Bodies/*genetics

  • Source: Nature communications [Nat Commun] 2022 Jan 10; Vol. 13 (1), pp. 101. Date of Electronic Publication: 2022 Jan 10.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

DNA double strand break position leads to distinct gene expression changes and regulates VSG switching pathway choice.

  • Authors : Thivolle A; Institut Pasteur, Université de Paris, Trypanosome Molecular Biology, Department of Parasites and Insect Vectors, Paris, France.; Mehnert AK

Subjects: Antigenic Variation* ; DNA Breaks, Double-Stranded*; DNA, Protozoan/DNA, Protozoan/DNA, Protozoan/*genetics

  • Source: PLoS pathogens [PLoS Pathog] 2021 Nov 12; Vol. 17 (11), pp. e1010038. Date of Electronic Publication: 2021 Nov 12 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Nanobody-mediated macromolecular crowding induces membrane fission and remodeling in the African trypanosome.

  • Authors : Hempelmann A; Division of Structural Biology of Infection and Immunity, German Cancer Research Center, Heidelberg 69120, Germany.; Hartleb L

Subjects: Cell Membrane/Cell Membrane/Cell Membrane/*drug effects ; Cell Movement/Cell Movement/Cell Movement/*drug effects ; Single-Domain Antibodies/Single-Domain Antibodies/Single-Domain Antibodies/*pharmacology

  • Source: Cell reports [Cell Rep] 2021 Nov 02; Vol. 37 (5), pp. 109923.Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247

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Academic Journal

Dynamic, variable oligomerization and the trafficking of variant surface glycoproteins of Trypanosoma brucei.

  • Authors : Umaer K; Department of Microbiology and Immunology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo (SUNY), Buffalo, New York, USA.; Eurofins, Spring House, Pennsylvania, USA.

Subjects: Trypanosoma brucei brucei* ; Variant Surface Glycoproteins, Trypanosoma*/Variant Surface Glycoproteins, Trypanosoma*/Variant Surface Glycoproteins, Trypanosoma*/genetics; Cell Membrane

  • Source: Traffic (Copenhagen, Denmark) [Traffic] 2021 Aug; Vol. 22 (8), pp. 274-283. Date of Electronic Publication: 2021 Jun 29.Publisher: Wiley Country of Publication: England NLM ID: 100939340 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0854

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Academic Journal

Structure of trypanosome coat protein VSGsur and function in suramin resistance.

  • Authors : Zeelen J; Division of Structural Biology of Infection and Immunity, German Cancer Research Center, Heidelberg, Germany.; van Straaten M

Subjects: Drug Resistance/Drug Resistance/Drug Resistance/*immunology ; Suramin/Suramin/Suramin/*metabolism ; Trypanosoma brucei rhodesiense/Trypanosoma brucei rhodesiense/Trypanosoma brucei rhodesiense/*immunology

  • Source: Nature microbiology [Nat Microbiol] 2021 Mar; Vol. 6 (3), pp. 392-400. Date of Electronic Publication: 2021 Jan 18.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101674869 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  14,088 results for ""Variant Surface Glycoproteins, Trypanosoma""