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Academic Journal

Anti-TL1A monoclonal antibody modulates the dysregulation of Th1/Th17 cells and attenuates granuloma formation in sarcoidosis by inhibiting the PI3K/AKT signaling pathway.

  • Authors : Ma C; Department of Respiratory and Critical Care Medicine, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.; Huang J

Subjects: Th1 Cells*/Th1 Cells*/Th1 Cells*/immunology ; Th17 Cells*/Th17 Cells*/Th17 Cells*/immunology ; Signal Transduction*/Signal Transduction*/Signal Transduction*/drug effects

  • Source: International immunopharmacology [Int Immunopharmacol] 2024 Aug 20; Vol. 137, pp. 112360. Date of Electronic Publication: 2024 Jun 08.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

TL1A priming induces a multi-cytokine Th9 cell phenotype that promotes robust allergic inflammation in murine models of asthma.

  • Authors : Niese ML; Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, USA.; Pajulas AL

Subjects: Asthma*/Asthma*/Asthma*/immunology ; Asthma*/Asthma*/Asthma*/metabolism ; Tumor Necrosis Factor Ligand Superfamily Member 15*/Tumor Necrosis Factor Ligand Superfamily Member 15*/Tumor Necrosis Factor Ligand Superfamily Member 15*/metabolism

  • Source: Mucosal immunology [Mucosal Immunol] 2024 Aug; Vol. 17 (4), pp. 537-553. Date of Electronic Publication: 2024 Mar 15.Publisher: Elsevier Country of Publication: United States NLM ID: 101299742 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Phase 2 Trial of Anti-TL1A Monoclonal Antibody Tulisokibart for Ulcerative Colitis.

Subjects: Antibodies, Monoclonal*/Antibodies, Monoclonal*/Antibodies, Monoclonal*/administration & dosage ; Antibodies, Monoclonal*/Antibodies, Monoclonal*/Antibodies, Monoclonal*/adverse effects ; Colitis, Ulcerative*/Colitis, Ulcerative*/Colitis, Ulcerative*/diagnosis

  • Source: The New England journal of medicine [N Engl J Med] 2024 Sep 26; Vol. 391 (12), pp. 1119-1129.Publisher: Massachusetts Medical Society Country of Publication: United States NLM ID: 0255562 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Targeting TNFRSF25 by agonistic antibodies and multimeric TL1A proteins co-stimulated CD8 + T cells and inhibited tumor growth.

  • Authors : Lyu X; Peking University-Tsinghua University-National Institute of Biological Sciences Joint Graduate Program, School of Life Sciences, Tsinghua University, Beijing, China.; National Institute of Biological Sciences, Beijing, China.

Subjects: CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/immunology ; Tumor Necrosis Factor Ligand Superfamily Member 15* ; Receptors, Tumor Necrosis Factor, Member 25*

  • Source: Journal for immunotherapy of cancer [J Immunother Cancer] 2024 Aug 13; Vol. 12 (8). Date of Electronic Publication: 2024 Aug 13.Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101620585 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

TL1A and IL-18 synergy promotes GM-CSF-dependent thymic granulopoiesis in mice.

  • Authors : Ruiz Pérez M; Molecular Signaling and Cell Death Unit, VIB-UGent Center for Inflammation Research, Flanders Institute for Biotechnology, Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.

Subjects: Interleukin-18*/Interleukin-18*/Interleukin-18*/metabolism ; Thymus Gland*/Thymus Gland*/Thymus Gland*/immunology ; Granulocyte-Macrophage Colony-Stimulating Factor*/Granulocyte-Macrophage Colony-Stimulating Factor*/Granulocyte-Macrophage Colony-Stimulating Factor*/metabolism

  • Source: Cellular & molecular immunology [Cell Mol Immunol] 2024 Aug; Vol. 21 (8), pp. 807-825. Date of Electronic Publication: 2024 Jun 05.Publisher: Chinese Society of Immunology;; _b Nature Pub. Group Country of Publication: China NLM ID: 101242872 Publication Model: Print-Electronic Cited

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Academic Journal

Necroptosis plays a role in TL1A-induced airway inflammation and barrier damage in asthma.

  • Authors : Liu X; Department of Respiratory, Shandong Institute of Respiratory Diseases, The First Affiliated Hospital of Shandong First Medical University, Jinan, 250014, China.; Zhang J

Subjects: Asthma*/Asthma*/Asthma*/metabolism ; Asthma*/Asthma*/Asthma*/pathology ; Necroptosis*/Necroptosis*/Necroptosis*/physiology

  • Source: Respiratory research [Respir Res] 2024 Jul 10; Vol. 25 (1), pp. 271. Date of Electronic Publication: 2024 Jul 10.Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101090633 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

TL1A Promotes Fibrogenesis in Colonic Fibroblasts via the TGF-β1/Smad3 Signaling Pathway.

  • Authors : Song J; Department of Gastroenterology, The Second Hospital of Hebei Medical University, Hebei Key Laboratory of Gastroenterology, Hebei Institute of Gastroenterology, Hebei Clinical Research Center for Digestive Diseases, Shijiazhuang, 050000, China.; Sun DL

Subjects: Tumor Necrosis Factor Ligand Superfamily Member 15*/Tumor Necrosis Factor Ligand Superfamily Member 15*/Tumor Necrosis Factor Ligand Superfamily Member 15*/metabolism ; Tumor Necrosis Factor Ligand Superfamily Member 15*/Tumor Necrosis Factor Ligand Superfamily Member 15*/Tumor Necrosis Factor Ligand Superfamily Member 15*/genetics ; Smad3 Protein*/Smad3 Protein*/Smad3 Protein*/metabolism

  • Source: Current medical science [Curr Med Sci] 2024 Jun; Vol. 44 (3), pp. 519-528. Date of Electronic Publication: 2024 Jun 06.Publisher: Huazhong University of Science and Technology Country of Publication: China NLM ID: 101729993 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

TL1A inhibition for inflammatory bowel disease treatment: From inflammation to fibrosis.

  • Authors : Solitano V; Division of Gastroenterology, Western University, London, ON, Canada; Gastroenterology and Endoscopy, IRCCS Ospedale San Raffaele and Vita-Salute San Raffaele University, Milan, Italy.

Subjects: Fibrosis*/Fibrosis*/Fibrosis*/drug therapy ; Tumor Necrosis Factor Ligand Superfamily Member 15*/Tumor Necrosis Factor Ligand Superfamily Member 15*/Tumor Necrosis Factor Ligand Superfamily Member 15*/metabolism ; Tumor Necrosis Factor Ligand Superfamily Member 15*/Tumor Necrosis Factor Ligand Superfamily Member 15*/Tumor Necrosis Factor Ligand Superfamily Member 15*/genetics

  • Source: Med (New York, N.Y.) [Med] 2024 May 10; Vol. 5 (5), pp. 386-400. Date of Electronic Publication: 2024 Apr 03.Publisher: Cell Press Country of Publication: United States NLM ID: 101769215 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Antibodies Targeting the Tumor Necrosis Factor-Like Ligand 1A in Inflammatory Bowel Disease: A New Kid on the (Biologics) Block?

  • Authors : Schweckendiek D; Department of Gastroenterology and Hepatology, University Hospital Zurich, Zurich, Switzerland.; Rogler G

Subjects: Tumor Necrosis Factor Ligand Superfamily Member 15*/Tumor Necrosis Factor Ligand Superfamily Member 15*/Tumor Necrosis Factor Ligand Superfamily Member 15*/immunology ; Tumor Necrosis Factor Ligand Superfamily Member 15*/Tumor Necrosis Factor Ligand Superfamily Member 15*/Tumor Necrosis Factor Ligand Superfamily Member 15*/antagonists & inhibitors ; Inflammatory Bowel Diseases*/Inflammatory Bowel Diseases*/Inflammatory Bowel Diseases*/drug therapy

  • Source: Digestion [Digestion] 2024; Vol. 105 (6), pp. 411-418. Date of Electronic Publication: 2024 Jul 26.Publisher: Karger Country of Publication: Switzerland NLM ID: 0150472 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1421-9867

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Academic Journal

Tumor necrosis factor-like cytokine 1A plays a role in inflammatory bowel disease pathogenesis.

  • Authors : Meng F; Department of Immunology, Basic Medicine College, China Medical University, Shenyang, Liaoning Province 110122, China.; Department of Laboratory Medicine, The First Hospital of China Medical University, Shenyang, Liaoning Province 110801, China.

Subjects: Tumor Necrosis Factor Ligand Superfamily Member 15*/Tumor Necrosis Factor Ligand Superfamily Member 15*/Tumor Necrosis Factor Ligand Superfamily Member 15*/genetics ; Tumor Necrosis Factor Ligand Superfamily Member 15*/Tumor Necrosis Factor Ligand Superfamily Member 15*/Tumor Necrosis Factor Ligand Superfamily Member 15*/metabolism ; Inflammatory Bowel Diseases*/Inflammatory Bowel Diseases*/Inflammatory Bowel Diseases*/metabolism

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Aug 22; Vol. 120 (34), pp. e2120771120. Date of Electronic Publication: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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  • 1-10 of  592 results for ""Tumor Necrosis Factor Ligand Superfamily Member 15""