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Academic Journal

Transcriptome profiles of Trypanosoma brucei rhodesiense in Malawi reveal focus specific gene expression profiles associated with pathology.

Subjects: Trypanosoma brucei rhodesiense*/Trypanosoma brucei rhodesiense*/Trypanosoma brucei rhodesiense*/genetics ; Transcriptome* ; Trypanosomiasis, African*/Trypanosomiasis, African*/Trypanosomiasis, African*/parasitology

  • Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2024 May 03; Vol. 18 (5), pp. e0011516. Date of Electronic Publication: 2024 May 03 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Ginkgo biloba attenuated detrimental inflammatory and oxidative events due to Trypanosoma brucei rhodesiense in mice treated with melarsoprol.

  • Authors : Wendo JK; The University of Nairobi, Department of Public Health, Pharmacology and Toxicology, Kangemi (Nairobi), Kenya.; The Technical University of Kenya, Department of Pharmaceutical Sciences and Technology, Nairobi, Kenya.

Subjects: Trypanosomiasis, African*/Trypanosomiasis, African*/Trypanosomiasis, African*/drug therapy ; Trypanosomiasis, African*/Trypanosomiasis, African*/Trypanosomiasis, African*/parasitology ; Oxidative Stress*/Oxidative Stress*/Oxidative Stress*/drug effects

  • Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2024 Apr 15; Vol. 18 (4), pp. e0012103. Date of Electronic Publication: 2024 Apr 15 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Target product profile: diagnostic test for Trypanosoma brucei rhodesiense .

  • Authors : Priotto G; Department of Control of Neglected Tropical Diseases, World Health Organization, Avenue Appia 20, 1211 Geneva 27, Switzerland.; Franco JR

Subjects: Trypanosoma brucei rhodesiense* ; Trypanosomiasis, African*/Trypanosomiasis, African*/Trypanosomiasis, African*/diagnosis ; Trypanosomiasis, African*/Trypanosomiasis, African*/Trypanosomiasis, African*/epidemiology

  • Source: Bulletin of the World Health Organization [Bull World Health Organ] 2023 Aug 01; Vol. 101 (8), pp. 529-534. Date of Electronic Publication: 2023 Jun 26.Publisher: World Health Organization Country of Publication: Switzerland NLM ID: 7507052 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Pemuchiamides A and B, Proline-Rich Linear Lipopeptides, Isolated from a Marine Hormoscilla sp. Cyanobacterium.

  • Authors : Irie K; Department of Applied Chemistry, Chuo University, 1-13-27 Kasuga, Bunkyo-ku, Tokyo 112-8551, Japan.; Jeelani G

Subjects: Cyanobacteria*/Cyanobacteria*/Cyanobacteria*/chemistry ; Marine Biology* ; Trypanosoma brucei rhodesiense*/Trypanosoma brucei rhodesiense*/Trypanosoma brucei rhodesiense*/drug effects

  • Source: Journal of natural products [J Nat Prod] 2024 Sep 27; Vol. 87 (9), pp. 2292-2301. Date of Electronic Publication: 2024 Aug 15.Publisher: American Society of Pharmacognosy Country of Publication: United States NLM ID: 7906882 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Dipeptide Nitrile CD34 with Curcumin: A New Improved Combination Strategy to Synergistically Inhibit Rhodesain of Trypanosoma brucei rhodesiense .

  • Authors : Di Chio C; Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Viale Ferdinando Stagno d'Alcontres 31, 98166 Messina, Italy.; Department of Clinical and Experimental Medicine, University of Messina, Via C. Valeria, 98125 Messina, Italy.

Subjects: Curcumin*/Curcumin*/Curcumin*/pharmacology ; Trypanosoma brucei rhodesiense*/Trypanosoma brucei rhodesiense*/Trypanosoma brucei rhodesiense*/drug effects; Cysteine Proteinase Inhibitors/Cysteine Proteinase Inhibitors/Cysteine Proteinase Inhibitors/pharmacology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 May 09; Vol. 24 (10). Date of Electronic Publication: 2023 May 09.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Novel quinoline derivatives with broad-spectrum antiprotozoal activities.

  • Authors : Hartman CB; Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom, South Africa.; Dube PS

Subjects: Quinolines*/Quinolines*/Quinolines*/pharmacology ; Quinolines*/Quinolines*/Quinolines*/chemical synthesis ; Quinolines*/Quinolines*/Quinolines*/chemistry

  • Source: Archiv der Pharmazie [Arch Pharm (Weinheim)] 2024 Jun; Vol. 357 (6), pp. e2300319. Date of Electronic Publication: 2024 Feb 23.Publisher: Wiley-VCH Verlag GmbH & Co. KGaA Country of Publication: Germany NLM ID: 0330167 Publication Model: Print-Electronic Cited Medium: Internet

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Development of Novel Peptidyl Nitriles Targeting Rhodesain and Falcipain-2 for the Treatment of Sleeping Sickness and Malaria.

  • Authors : Di Chio C; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno d'Alcontres, 98166 Messina, Italy.; Starvaggi J

Subjects: Cysteine Proteinase Inhibitors*/Cysteine Proteinase Inhibitors*/Cysteine Proteinase Inhibitors*/pharmacology ; Cysteine Proteinase Inhibitors*/Cysteine Proteinase Inhibitors*/Cysteine Proteinase Inhibitors*/therapeutic use ; Cysteine Proteinase Inhibitors*/Cysteine Proteinase Inhibitors*/Cysteine Proteinase Inhibitors*/chemistry

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Apr 17; Vol. 25 (8). Date of Electronic Publication: 2024 Apr 17.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Trypanosoma brucei rhodesiense Inhibitor of Cysteine Peptidase (ICP) Is Required for Virulence in Mice and to Attenuate the Inflammatory Response.

  • Authors : Costa TFR; Instituto de Biofisica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-901, Brazil.; Goundry A

Subjects: Trypanosoma brucei rhodesiense*/Trypanosoma brucei rhodesiense*/Trypanosoma brucei rhodesiense*/pathogenicity ; Trypanosomiasis, African*/Trypanosomiasis, African*/Trypanosomiasis, African*/parasitology ; Protozoan Proteins*/Protozoan Proteins*/Protozoan Proteins*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2022 Dec 30; Vol. 24 (1). Date of Electronic Publication: 2022 Dec 30.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Drug Combination Studies of the Dipeptide Nitrile CD24 with Curcumin: A New Strategy to Synergistically Inhibit Rhodesain of Trypanosoma brucei rhodesiense .

  • Authors : Di Chio C; Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Viale Ferdinando Stagno d'Alcontres 31, 98166 Messina, Italy.; Previti S

Subjects: Trypanosoma brucei rhodesiense* ; Curcumin*/Curcumin*/Curcumin*/pharmacology; Humans

  • Source: International journal of molecular sciences [Int J Mol Sci] 2022 Nov 21; Vol. 23 (22). Date of Electronic Publication: 2022 Nov 21.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Development of novel dipeptide nitriles as inhibitors of rhodesain of Trypanosoma brucei rhodesiense.

  • Authors : Di Chio C; Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Viale Ferdinando Stagno d'Alcontres, 31 - 98166, Messina, Italy.; Previti S

Subjects: Cysteine Proteinase Inhibitors*/Cysteine Proteinase Inhibitors*/Cysteine Proteinase Inhibitors*/chemistry ; Cysteine Proteinase Inhibitors*/Cysteine Proteinase Inhibitors*/Cysteine Proteinase Inhibitors*/pharmacology ; Dipeptides*/Dipeptides*/Dipeptides*/chemistry

  • Source: European journal of medicinal chemistry [Eur J Med Chem] 2022 Jun 05; Vol. 236, pp. 114328. Date of Electronic Publication: 2022 Mar 29.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet

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  • 1-10 of  9,259 results for ""Trypanosoma brucei rhodesiense""