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Academic Journal

Live-cell imaging of RNA Pol II and elongation factors distinguishes competing mechanisms of transcription regulation.

  • Authors : Versluis P; Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA.; Graham TGW

Subjects: RNA Polymerase II*/RNA Polymerase II*/RNA Polymerase II*/metabolism ; RNA Polymerase II*/RNA Polymerase II*/RNA Polymerase II*/genetics ; Drosophila melanogaster*/Drosophila melanogaster*/Drosophila melanogaster*/genetics

  • Source: Molecular cell [Mol Cell] 2024 Aug 08; Vol. 84 (15), pp. 2856-2869.e9.Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print Cited Medium: Internet ISSN: 1097-4164

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Academic Journal

Identification of TEFM as a potential therapeutic target for LUAD treatment.

  • Authors : Hu W; Institute of Thoracic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, China.; Department of Thoracic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, China.

Subjects: Mitochondria*/Mitochondria*/Mitochondria*/metabolism ; Transcriptional Elongation Factors*/Transcriptional Elongation Factors*/Transcriptional Elongation Factors*/metabolism ; Transcriptional Elongation Factors*/Transcriptional Elongation Factors*/Transcriptional Elongation Factors*/genetics

  • Source: Journal of translational medicine [J Transl Med] 2024 Jul 29; Vol. 22 (1), pp. 692. Date of Electronic Publication: 2024 Jul 29.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

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Academic Journal

Structural basis of archaeal RNA polymerase transcription elongation and Spt4/5 recruitment.

  • Authors : Tarău D; Institute of Microbiology & Archaea Centre, Single-Molecule Biochemistry Lab, University of Regensburg, 93053 Regensburg, Germany.; Grünberger F

Subjects: Archaeal Proteins*/Archaeal Proteins*/Archaeal Proteins*/chemistry ; Archaeal Proteins*/Archaeal Proteins*/Archaeal Proteins*/metabolism ; Archaeal Proteins*/Archaeal Proteins*/Archaeal Proteins*/genetics

  • Source: Nucleic acids research [Nucleic Acids Res] 2024 Jun 10; Vol. 52 (10), pp. 6017-6035.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

FACT maintains chromatin architecture and thereby stimulates RNA polymerase II pausing during transcription in vivo.

  • Authors : Žumer K; Max Planck Institute for Multidisciplinary Sciences, Department of Molecular Biology, Am Fassberg 11, 37077 Göttingen, Germany. Electronic address: .; Ochmann M

Subjects: RNA Polymerase II*/RNA Polymerase II*/RNA Polymerase II*/metabolism ; RNA Polymerase II*/RNA Polymerase II*/RNA Polymerase II*/genetics ; Transcriptional Elongation Factors*/Transcriptional Elongation Factors*/Transcriptional Elongation Factors*/metabolism

  • Source: Molecular cell [Mol Cell] 2024 Jun 06; Vol. 84 (11), pp. 2053-2069.e9. Date of Electronic Publication: 2024 May 28.Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Chromatin regulates alternative polyadenylation via the RNA polymerase II elongation rate.

  • Authors : Geisberg JV; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115.; Moqtaderi Z

Subjects: RNA Polymerase II*/RNA Polymerase II*/RNA Polymerase II*/metabolism ; RNA Polymerase II*/RNA Polymerase II*/RNA Polymerase II*/genetics ; Polyadenylation*

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 May 21; Vol. 121 (21), pp. e2405827121. Date of Electronic Publication: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Distinct roles of two SEC scaffold proteins, AFF1 and AFF4, in regulating RNA polymerase II transcription elongation.

  • Authors : Che Z; The Key Laboratory of Developmental Genes and Human Disease, School of Life Science and Technology, Southeast University, Nanjing 210096, China.; Liu X

Subjects: RNA Polymerase II*/RNA Polymerase II*/RNA Polymerase II*/metabolism ; Transcriptional Elongation Factors*/Transcriptional Elongation Factors*/Transcriptional Elongation Factors*/metabolism ; Transcriptional Elongation Factors*/Transcriptional Elongation Factors*/Transcriptional Elongation Factors*/genetics

  • Source: Journal of molecular cell biology [J Mol Cell Biol] 2024 Jan 17; Vol. 15 (8).Publisher: Oxford University Press Country of Publication: United States NLM ID: 101503669 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

The Biological Significance of AFF4: Promoting Transcription Elongation, Osteogenic Differentiation and Tumor Progression.

  • Authors : Long Q; Department of Orthodontics II, Affiliated Stomatological Hospital of Zunyi Medical University, Zunyi, 563000, China.; Oral Disease Research Key Laboratory of Guizhou Tertiary Institution, School of Stomatology, Zunyi Medical University, Zunyi, 563006, China.

Subjects: Transcriptional Elongation Factors*/Transcriptional Elongation Factors*/Transcriptional Elongation Factors*/metabolism ; Cell Differentiation* ; Neoplasms*/Neoplasms*/Neoplasms*/pathology

  • Source: Combinatorial chemistry & high throughput screening [Comb Chem High Throughput Screen] 2024; Vol. 27 (10), pp. 1403-1412.Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 9810948 Publication Model: Print Cited Medium: Internet

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Academic Journal

The N-terminus of Spt16 anchors FACT to MCM2-7 for parental histone recycling.

  • Authors : Wang X; State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences and Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, 100871, China.; Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, 100871, China.

Subjects: Histones*/Histones*/Histones*/metabolism ; Saccharomyces cerevisiae Proteins*/Saccharomyces cerevisiae Proteins*/Saccharomyces cerevisiae Proteins*/metabolism ; Transcriptional Elongation Factors*/Transcriptional Elongation Factors*/Transcriptional Elongation Factors*/metabolism

  • Source: Nucleic acids research [Nucleic Acids Res] 2023 Nov 27; Vol. 51 (21), pp. 11549-11567.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Binding of small molecule inhibitors to RNA polymerase-Spt5 complex impacts RNA and DNA stability.

  • Authors : Gallardo A; Department of Molecular and Cell Biology, University of California Merced, 5200 North Lake Rd, Merced, CA, 95343, USA.; Dutagaci B

Subjects: RNA* ; RNA Polymerase II* ; Transcriptional Elongation Factors*

  • Source: Journal of computer-aided molecular design [J Comput Aided Mol Des] 2023 Nov 21; Vol. 38 (1), pp. 1. Date of Electronic Publication: 2023 Nov 21.Publisher: Springer Country of Publication: Netherlands NLM ID: 8710425 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-4951

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Academic Journal

A novel ELP1 mutation impairs the function of the Elongator complex and causes a severe neurodevelopmental phenotype.

  • Authors : Kojic M; Frazer Institute, The University of Queensland, Woolloongabba, QLD, 4102, Australia.; Abbassi NEH

Subjects: Mutation, Missense* ; Transcriptional Elongation Factors*/Transcriptional Elongation Factors*/Transcriptional Elongation Factors*/genetics ; Neurodevelopmental Disorders*/Neurodevelopmental Disorders*/Neurodevelopmental Disorders*/genetics

  • Source: Journal of human genetics [J Hum Genet] 2023 Jul; Vol. 68 (7), pp. 445-453. Date of Electronic Publication: 2023 Mar 02.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 9808008 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  2,255 results for ""Transcriptional Elongation Factors""