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Academic Journal

The pivotal role of the Hes1/Piezo1 pathway in the pathophysiology of glucocorticoid-induced osteoporosis.

  • Authors : Ochiai N; Department of Musculoskeletal Regenerative Medicine, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan.; Taisho Pharmaceutical Co., Ltd., Saitama, Japan.

Subjects: Osteoporosis*/Osteoporosis*/Osteoporosis*/chemically induced ; Osteoporosis*/Osteoporosis*/Osteoporosis*/metabolism ; Osteoporosis*/Osteoporosis*/Osteoporosis*/pathology

  • Source: JCI insight [JCI Insight] 2024 Dec 06; Vol. 9 (23). Date of Electronic Publication: 2024 Dec 06.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium:

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Academic Journal

HES1 revitalizes the functionality of aged adipose-derived stem cells by inhibiting the transcription of STAT1.

  • Authors : Li C; Department of Hand Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1277 Jiefang Avenue, Wuhan, 430022, China.; Ren S

Subjects: Transcription Factor HES-1*/Transcription Factor HES-1*/Transcription Factor HES-1*/metabolism ; Transcription Factor HES-1*/Transcription Factor HES-1*/Transcription Factor HES-1*/genetics ; STAT1 Transcription Factor*/STAT1 Transcription Factor*/STAT1 Transcription Factor*/metabolism

  • Source: Stem cell research & therapy [Stem Cell Res Ther] 2024 Nov 05; Vol. 15 (1), pp. 399. Date of Electronic Publication: 2024 Nov 05.Publisher: BioMed Central Country of Publication: England NLM ID: 101527581 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-6512

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Academic Journal

HES1 potentiates high salt stress response as an enhancer of NFAT5-DNA binding.

  • Authors : Ryuno H; Laboratory of Cell Signaling, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.; Hanafusa Y

Subjects: Transcription Factor HES-1*/Transcription Factor HES-1*/Transcription Factor HES-1*/metabolism ; Transcription Factor HES-1*/Transcription Factor HES-1*/Transcription Factor HES-1*/genetics; Humans

  • Source: Communications biology [Commun Biol] 2024 Oct 09; Vol. 7 (1), pp. 1290. Date of Electronic Publication: 2024 Oct 09.Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Blocking Gremlin1 inhibits M1 macrophage polarization through Notch1/Hes1 signaling pathway in apical periodontitis.

  • Authors : Guan XY; Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an, Shaanxi, China.; Clinical Research Center of Shaanxi Province for Dental and Maxillofacial Diseases, College of Stomatology, Xian Jiaotong University, Xi'an, Shaanxi, China.

Subjects: Periapical Periodontitis*/Periapical Periodontitis*/Periapical Periodontitis*/pathology ; Periapical Periodontitis*/Periapical Periodontitis*/Periapical Periodontitis*/metabolism ; Periapical Periodontitis*/Periapical Periodontitis*/Periapical Periodontitis*/immunology

  • Source: Immunopharmacology and immunotoxicology [Immunopharmacol Immunotoxicol] 2024 Oct; Vol. 46 (5), pp. 703-714. Date of Electronic Publication: 2024 Aug 27.Publisher: Informa Healthcare Country of Publication: England NLM ID: 8800150 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Curcumin pretreatment attenuates myocardial ischemia/reperfusion injury by inhibiting ferroptosis, autophagy and apoptosis via HES1.

  • Authors : Yuan Y; Department of Cardiovascular Surgery, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi 330006, P.R. China.; Huang H

Subjects: Myocardial Reperfusion Injury*/Myocardial Reperfusion Injury*/Myocardial Reperfusion Injury*/metabolism ; Myocardial Reperfusion Injury*/Myocardial Reperfusion Injury*/Myocardial Reperfusion Injury*/drug therapy ; Myocardial Reperfusion Injury*/Myocardial Reperfusion Injury*/Myocardial Reperfusion Injury*/pathology

  • Source: International journal of molecular medicine [Int J Mol Med] 2024 Dec; Vol. 54 (6). Date of Electronic Publication: 2024 Oct 04.Publisher: D.A. Spandidos Country of Publication: Greece NLM ID: 9810955 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

A NOTCH2 pathogenic variant and HES1 regulate osteoclastogenesis in induced pluripotent stem cells.

  • Authors : Canalis E; Department of Orthopaedic Surgery, UConn Health, Farmington, CT, USA; Department of Medicine, UConn Health, Farmington, CT, USA

Subjects: Receptor, Notch2*/Receptor, Notch2*/Receptor, Notch2*/metabolism ; Receptor, Notch2*/Receptor, Notch2*/Receptor, Notch2*/genetics ; Induced Pluripotent Stem Cells*/Induced Pluripotent Stem Cells*/Induced Pluripotent Stem Cells*/metabolism

  • Source: Bone [Bone] 2025 Feb; Vol. 191, pp. 117334. Date of Electronic Publication: 2024 Nov 19.Publisher: Elsevier Science Country of Publication: United States NLM ID: 8504048 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

IL-1β-induced pericyte dysfunction with a secretory phenotype exacerbates retinal microenvironment inflammation via Hes1/STAT3 signaling pathway.

  • Authors : Huang C; Xiamen Diabetes Institute, Fujian Province Key Laboratory of Translational Research for Diabetes, Department of Endocrinology and Diabetes, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China. Electronic address: .; Zhang X

Subjects: Pericytes*/Pericytes*/Pericytes*/metabolism ; Pericytes*/Pericytes*/Pericytes*/pathology ; Pericytes*/Pericytes*/Pericytes*/drug effects

  • Source: International immunopharmacology [Int Immunopharmacol] 2025 Jan 10; Vol. 144, pp. 113611. Date of Electronic Publication: 2024 Nov 28.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

MicroRNA-124a promoted the differentiation of bone marrow mesenchymal stem cells into neurons through Notch signal pathway.

  • Authors : Wang D; Department of Neurology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, No. 19 Xiuhua Road, Xiuying District, Haikou, 570311, Hainan, China.; Jing L

Subjects: Mesenchymal Stem Cells*/Mesenchymal Stem Cells*/Mesenchymal Stem Cells*/metabolism ; Mesenchymal Stem Cells*/Mesenchymal Stem Cells*/Mesenchymal Stem Cells*/drug effects ; MicroRNAs*/MicroRNAs*/MicroRNAs*/genetics

  • Source: European journal of medical research [Eur J Med Res] 2024 Sep 28; Vol. 29 (1), pp. 472. Date of Electronic Publication: 2024 Sep 28.Publisher: BioMed Central Country of Publication: England NLM ID: 9517857 Publication Model: Electronic Cited Medium: Internet ISSN: 2047-783X

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Academic Journal

Unravelling differential Hes1 dynamics during axis elongation of mouse embryos through single-cell tracking.

  • Authors : El Azhar Y; Hubrecht Institute-KNAW (Royal Netherlands Academy of Arts and Sciences), University Medical Center Utrecht, Utrecht 3584, The Netherlands.; Schulthess P

Subjects: Transcription Factor HES-1*/Transcription Factor HES-1*/Transcription Factor HES-1*/metabolism ; Transcription Factor HES-1*/Transcription Factor HES-1*/Transcription Factor HES-1*/genetics ; Single-Cell Analysis*

  • Source: Development (Cambridge, England) [Development] 2024 Sep 15; Vol. 151 (18). Date of Electronic Publication: 2024 Sep 26.Publisher: Company Of Biologists Limited Country of Publication: England NLM ID: 8701744 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

ADAM10 Alleviates Hypoxia/Reoxygenation-Induced Cardiomyocyte Injury by Activating the Notch Signaling Pathway.

  • Authors : Xu T; Department of Cardiology I, The Second Affiliated Hospital of Shandong First Medical University, Tai'an, 271000, China.; Jiang S

Subjects: Signal Transduction* ; ADAM10 Protein*/ADAM10 Protein*/ADAM10 Protein*/metabolism ; ADAM10 Protein*/ADAM10 Protein*/ADAM10 Protein*/genetics

  • Source: Cell biochemistry and biophysics [Cell Biochem Biophys] 2024 Sep; Vol. 82 (3), pp. 2523-2532. Date of Electronic Publication: 2024 Jun 24.Publisher: Humana Press Country of Publication: United States NLM ID: 9701934 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  1,453 results for ""Transcription Factor HES-1""