Search Results

Benemerita Universidad Autonoma de Puebla (BUAP) Researchers Have Provided New Study Findings on Cancer (Correlation between Molecular Docking and the Stabilizing Interaction of HOMO-LUMO: Spirostans in CHK1 and CHK2, an In Silico Cancer ...)

• Source: Obesity, Fitness & Wellness Week. September 14, 2024, 767

Record details

Ruscogenin Exerts Anxiolytic-Like Effect via Microglial NF-κB/MAPKs/NLRP3 Signaling Pathways in Mouse Model of Chronic Inflammatory Pain.

• Authors : Qi JY; State Key Laboratory of Military Stomatology, National Clinical Research Center for Oral Diseases, Shaanxi International Joint Research Center for Oral Diseases, Department of Pharmacy, School of Stomatology, Fourth Military Medical University, Xi'an, China.; Department of Pharmacology, School of Pharmacy, Fourth Military Medical University, Xi'an, China.

Subjects: NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism ; NF-kappa B*/NF-kappa B*/NF-kappa B*/metabolism ; Microglia*/Microglia*/Microglia*/drug effects

• Source: Phytotherapy research : PTR [Phytother Res] 2024 Nov; Vol. 38 (11), pp. 5417-5440. Date of Electronic Publication: 2024 Sep 12.Publisher: Wiley Country of Publication: England NLM ID: 8904486 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1099-1573

Record details

Protective properties of Ophiopogonin D in DSS-induced colitis: insights into microbiota modulation.

• Authors : Zhang T; Department of Gastroenterology, Nanchong Central Hospital, The Second Clinical Medical College, North Sichuan Medical College, Nanchong, 637000, China. .; Guo Z

Subjects: Gastrointestinal Microbiome*/Gastrointestinal Microbiome*/Gastrointestinal Microbiome*/drug effects ; Saponins*/Saponins*/Saponins*/pharmacology ; Spirostans*/Spirostans*/Spirostans*/pharmacology

• Source: Inflammopharmacology [Inflammopharmacology] 2024 Oct; Vol. 32 (5), pp. 3553-3570. Date of Electronic Publication: 2024 Jul 22.Publisher: Birkhäuser Country of Publication: Switzerland NLM ID: 9112626 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details

Ruscogenin attenuates osteoarthritis by modulating oxidative stress-mediated macrophage reprogramming via directly targeting Sirt3.

• Authors : Liu Y; Department of Orthopedics, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230022, China; Graduate School, Bengbu Medical University, Bengbu 233000, China.

Subjects: Oxidative Stress*/Oxidative Stress*/Oxidative Stress*/drug effects ; Macrophages*/Macrophages*/Macrophages*/drug effects ; Macrophages*/Macrophages*/Macrophages*/immunology

• Source: International immunopharmacology [Int Immunopharmacol] 2024 Dec 25; Vol. 143 (Pt 1), pp. 113336. Date of Electronic Publication: 2024 Oct 07.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details

A systematic review of spirostanol saponins and anticancer natural products isolated from Tacca plantaginea (Hance) Drenth.

• Authors : Bailly C; University of Lille, CNRS, Inserm, CHU Lille, UMR9020 - UMR1277 - Canther - Cancer Heterogeneity, Plasticity and Resistance to Therapies, 59000, Lille, France; University of Lille, Faculty of Pharmacy, Institut de Chimie Pharmaceutique Albert Lespagnol (ICPAL), 3 rue du Professeur Laguesse, 59000, Lille, France

Subjects: Antineoplastic Agents, Phytogenic*/Antineoplastic Agents, Phytogenic*/Antineoplastic Agents, Phytogenic*/pharmacology ; Antineoplastic Agents, Phytogenic*/Antineoplastic Agents, Phytogenic*/Antineoplastic Agents, Phytogenic*/isolation & purification ; Antineoplastic Agents, Phytogenic*/Antineoplastic Agents, Phytogenic*/Antineoplastic Agents, Phytogenic*/chemistry

• Source: Phytochemistry [Phytochemistry] 2024 Dec; Vol. 228, pp. 114252. Date of Electronic Publication: 2024 Aug 22.Publisher: Elsevier Country of Publication: England NLM ID: 0151434 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3700

Record details

Tributelosides A-D: Four Undescribed Spirostan Glycosides Isolated from the Branches and Leaves of Tribulus terrestris with Their NO Production Inhibitory Activity in LPS Activated RAW 264.7 Cells.

• Authors : Van Quoc N; School of chemistry, biology and environment, Vinh University, 182 Le Duan, Ben Thuy, Vinh City, Nghe An, 461010, Vietnam.; Huy Hoang N

Subjects: Lipopolysaccharides*/Lipopolysaccharides*/Lipopolysaccharides*/antagonists & inhibitors ; Lipopolysaccharides*/Lipopolysaccharides*/Lipopolysaccharides*/pharmacology ; Tribulus*/Tribulus*/Tribulus*/chemistry

• Source: Chemistry & biodiversity [Chem Biodivers] 2024 Aug; Vol. 21 (8), pp. e202401049. Date of Electronic Publication: 2024 Jun 25.Publisher: Verlag Helvetica Chimica Acta Country of Publication: Switzerland NLM ID: 101197449 Publication Model: Print-Electronic Cited Medium:

Record details

Polyhydroxylated Spirostanol Saponins from the Rhizomes of Paris dulongensis.

• Authors : Jia JK; Key Laboratory of Economic Plants and Biotechnology, Yunnan Key Laboratory for Wild Plant Resources, and State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, People's Republic of China.; University of Chinese Academy of Sciences, Beijing, 100049, People's Republic of China.

Subjects: Saponins*/Saponins*/Saponins*/isolation & purification ; Saponins*/Saponins*/Saponins*/pharmacology ; Saponins*/Saponins*/Saponins*/chemistry

• Source: Chemistry & biodiversity [Chem Biodivers] 2024 Jul; Vol. 21 (7), pp. e202400980. Date of Electronic Publication: 2024 Jun 25.Publisher: Verlag Helvetica Chimica Acta Country of Publication: Switzerland NLM ID: 101197449 Publication Model: Print-Electronic Cited Medium:

Record details

The Protective Effects of Ruscogenin Against Lipopolysaccharide-Induced Myocardial Injury in Septic Mice.

• Authors : Wang RY; Emergency Medicine Center, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.; Wang MG

Subjects: Lipopolysaccharides*/Lipopolysaccharides*/Lipopolysaccharides*/toxicity ; Myocytes, Cardiac*/Myocytes, Cardiac*/Myocytes, Cardiac*/drug effects ; Myocytes, Cardiac*/Myocytes, Cardiac*/Myocytes, Cardiac*/pathology

• Source: Journal of cardiovascular pharmacology [J Cardiovasc Pharmacol] 2024 Aug 01; Vol. 84 (2), pp. 175-187. Date of Electronic Publication: 2024 Aug 01.Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 7902492 Publication Model: Electronic Cited Medium: Internet

Record details

Ophiopogonin D' inhibited tumour growth and metastasis of anaplastic thyroid cancer by modulating JUN/RGS4 signalling.

• Authors : Xu T; Center for Clinical Pharmacy, Cancer Center, Department of Pharmacy, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China.; Key Laboratory of Endocrine Gland Diseases of Zhejiang Province, Hangzhou, Zhejiang, China.

Subjects: Thyroid Carcinoma, Anaplastic*/Thyroid Carcinoma, Anaplastic*/Thyroid Carcinoma, Anaplastic*/drug therapy ; Thyroid Carcinoma, Anaplastic*/Thyroid Carcinoma, Anaplastic*/Thyroid Carcinoma, Anaplastic*/metabolism ; Thyroid Carcinoma, Anaplastic*/Thyroid Carcinoma, Anaplastic*/Thyroid Carcinoma, Anaplastic*/pathology

• Source: Journal of cellular and molecular medicine [J Cell Mol Med] 2024 Aug; Vol. 28 (16), pp. e70014.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101083777 Publication Model: Print Cited Medium: Internet ISSN: 1582-4934

Record details

Ophiopogonin D alleviates acute lung injury by regulating inflammation via the STAT3/A20/ASK1 axis.

• Authors : Shen X; The Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou 310053, China.; Ruan Y

Subjects: Acute Lung Injury*/Acute Lung Injury*/Acute Lung Injury*/drug therapy ; Acute Lung Injury*/Acute Lung Injury*/Acute Lung Injury*/chemically induced ; Saponins*/Saponins*/Saponins*/pharmacology

• Source: Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2024 Jul 25; Vol. 130, pp. 155482. Date of Electronic Publication: 2024 Mar 15.Publisher: Urban & Fischer Verlag Country of Publication: Germany NLM ID: 9438794 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details