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Academic Journal

Ceramide lowering rescues respiratory defects in a Drosophila model of acid sphingomyelinase deficiency.

  • Authors : Hull AJ; Institute of Healthy Ageing, Department of Genetics, Evolution and Environment, University College London, Darwin Building, Gower Street, London, WC1E 6BT, United Kingdom.; Atilano ML

Subjects: Sphingomyelin Phosphodiesterase*/Sphingomyelin Phosphodiesterase*/Sphingomyelin Phosphodiesterase*/genetics ; Sphingomyelin Phosphodiesterase*/Sphingomyelin Phosphodiesterase*/Sphingomyelin Phosphodiesterase*/metabolism ; Ceramides*/Ceramides*/Ceramides*/metabolism

  • Source: Human molecular genetics [Hum Mol Genet] 2024 Dec 06; Vol. 33 (24), pp. 2111-2122.Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model: Print Cited Medium: Internet ISSN:

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Sphingolipid Levels and Processing of the Retinyl Chromophore in the Retina of a Mouse Model of Niemann-Pick Disease.

  • Authors : Rahman B; Department of Ophthalmology, Medical University of South Carolina, Charleston, South Carolina, United States.; Anderson DMG

Subjects: Disease Models, Animal* ; Sphingolipids*/Sphingolipids*/Sphingolipids*/metabolism ; Retinal Pigment Epithelium*/Retinal Pigment Epithelium*/Retinal Pigment Epithelium*/metabolism

  • Source: Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2024 Dec 02; Vol. 65 (14), pp. 24.Publisher: Association For Research In Vision And Ophthalmology (Arvo) Country of Publication: United States NLM ID: 7703701 Publication Model: Print Cited

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Academic Journal

SMPD4-mediated sphingolipid metabolism regulates brain and primary cilia development.

  • Authors : Inskeep KA; Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.; Steve and Cindy Rasmussen Institute for Genomic Medicine, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH 43205, USA.

Subjects: Cilia*/Cilia*/Cilia*/metabolism ; Ceramides*/Ceramides*/Ceramides*/metabolism ; Sphingolipids*/Sphingolipids*/Sphingolipids*/metabolism

  • Source: Development (Cambridge, England) [Development] 2024 Nov 15; Vol. 151 (22). Date of Electronic Publication: 2024 Nov 15.Publisher: Company Of Biologists Limited Country of Publication: England NLM ID: 8701744 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Acid Sphingomyelinase Activation and ROS Generation Potentiate Antiproliferative Effects of Mitomycin in HCC.

  • Authors : Buitkamp S; Pharmazentrum Frankfurt, Institut für Allgemeine Pharmakologie und Toxikologie, Goethe University Hospital, 60590 Frankfurt am Main, Germany.; Klinik für Innere Medizin I, Helios Dr. Horst Schmidt Kliniken Wiesbaden, 65199 Wiesbaden, Germany.

Subjects: Sphingomyelin Phosphodiesterase*/Sphingomyelin Phosphodiesterase*/Sphingomyelin Phosphodiesterase*/metabolism ; Sphingomyelin Phosphodiesterase*/Sphingomyelin Phosphodiesterase*/Sphingomyelin Phosphodiesterase*/genetics ; Mitomycin*/Mitomycin*/Mitomycin*/pharmacology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Nov 13; Vol. 25 (22). Date of Electronic Publication: 2024 Nov 13.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Newborn screening for acid sphingomyelinase deficiency in Illinois: A single center's experience.

  • Authors : Hickey RE; Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, USA.; Baker J

Subjects: Neonatal Screening*/Neonatal Screening*/Neonatal Screening*/methods ; Sphingomyelin Phosphodiesterase*/Sphingomyelin Phosphodiesterase*/Sphingomyelin Phosphodiesterase*/genetics ; Sphingomyelin Phosphodiesterase*/Sphingomyelin Phosphodiesterase*/Sphingomyelin Phosphodiesterase*/deficiency

  • Source: Journal of inherited metabolic disease [J Inherit Metab Dis] 2024 Nov; Vol. 47 (6), pp. 1363-1370. Date of Electronic Publication: 2024 Jul 11.Publisher: Wiley Country of Publication: United States NLM ID: 7910918 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-2665

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Academic Journal

The acid sphingomyelinase inhibitor imipramine enhances the release of UV photoproduct-containing DNA in small extracellular vesicles in UVB-irradiated human skin.

  • Authors : Carpenter MA; Department of Pharmacology and Toxicology, Wright State University Boonshoft School of Medicine, Dayton, Ohio, USA.; Thyagarajan A

Subjects: Imipramine*/Imipramine*/Imipramine*/pharmacology ; Ultraviolet Rays* ; Sphingomyelin Phosphodiesterase*/Sphingomyelin Phosphodiesterase*/Sphingomyelin Phosphodiesterase*/metabolism

  • Source: Photochemistry and photobiology [Photochem Photobiol] 2024 Nov-Dec; Vol. 100 (6), pp. 1894-1901. Date of Electronic Publication: 2024 Mar 03.Publisher: American Society for Photobiology Country of Publication: United States NLM ID: 0376425 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Chronic acid sphingomyelinase deficiency diagnosed in infancy/childhood in Polish patients: 2024 update.

  • Authors : Lipiński P; Institute of Clinical Sciences, Maria Skłodowska-Curie Medical Academy, Warsaw, Poland.; Ługowska A

Subjects: Sphingomyelin Phosphodiesterase*/Sphingomyelin Phosphodiesterase*/Sphingomyelin Phosphodiesterase*/genetics ; Sphingomyelin Phosphodiesterase*/Sphingomyelin Phosphodiesterase*/Sphingomyelin Phosphodiesterase*/deficiency; Humans

  • Source: Advances in clinical and experimental medicine : official organ Wroclaw Medical University [Adv Clin Exp Med] 2024 Oct; Vol. 33 (10), pp. 1163-1168.Publisher: Wroclaw Medical University Country of Publication: Poland NLM ID: 101138582 Publication Model: Print Cited Medium: Print ISSN:

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Academic Journal

ASM variants in the spotlight: A structure-based atlas for unraveling pathogenic mechanisms in lysosomal acid sphingomyelinase.

  • Authors : Scrima S; Cancer Structural Biology, Center for Autophagy, Recycling and Disease, Danish Cancer Institute, 2100 Copenhagen, Denmark; Cancer Systems Biology, Section for Bioinformatics, Department of Health and Technology, Technical University of Denmark, 2800 Lyngby, Denmark.

Subjects: Sphingomyelin Phosphodiesterase*/Sphingomyelin Phosphodiesterase*/Sphingomyelin Phosphodiesterase*/genetics ; Sphingomyelin Phosphodiesterase*/Sphingomyelin Phosphodiesterase*/Sphingomyelin Phosphodiesterase*/metabolism ; Lysosomes*/Lysosomes*/Lysosomes*/metabolism

  • Source: Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2024 Oct; Vol. 1870 (7), pp. 167260. Date of Electronic Publication: 2024 May 21.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731730 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

NEMO-Binding Domain/IKKγ Inhibitory Peptide Alleviates Neuronal Pyroptosis in Spinal Cord Injury by Inhibiting ASMase-Induced Lysosome Membrane Permeabilization.

  • Authors : Geng Y; Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, 325027, China.; Zhejiang Provincial Key Laboratory of Orthopaedics, Wenzhou, 325027, China.

Subjects: Lysosomes*/Lysosomes*/Lysosomes*/metabolism ; Lysosomes*/Lysosomes*/Lysosomes*/drug effects ; Pyroptosis*/Pyroptosis*/Pyroptosis*/drug effects

  • Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Oct; Vol. 11 (40), pp. e2405759. Date of Electronic Publication: 2024 Sep 03.Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844

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Academic Journal

Evidence that keratinocyte microvesicle particles carrying platelet-activating factor mediate the widespread multiorgan damage associated with intoxicated thermal burn injury.

  • Authors : Lohade RP; Department of Pharmacology and Toxicology, Wright State University, 3640 Colonel Glenn Highway, Dayton, Ohio 45435, United States.; Brewer C

Subjects: Burns*/Burns*/Burns*/pathology ; Burns*/Burns*/Burns*/complications ; Keratinocytes*/Keratinocytes*/Keratinocytes*/metabolism

  • Source: Journal of leukocyte biology [J Leukoc Biol] 2024 Oct 01; Vol. 116 (4), pp. 766-778.Publisher: Oxford University Press Country of Publication: England NLM ID: 8405628 Publication Model: Print Cited Medium: Internet ISSN:

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  • 1-10 of  7,323 results for ""Sphingomyelin Phosphodiesterase""