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Academic Journal

Molecular impact of mutations in RNA splicing factors in cancer.

  • Authors : Zhang Q; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Ai Y

Subjects: Neoplasms*/Neoplasms*/Neoplasms*/genetics ; Neoplasms*/Neoplasms*/Neoplasms*/metabolism ; RNA Splicing Factors*/RNA Splicing Factors*/RNA Splicing Factors*/genetics

  • Source: Molecular cell [Mol Cell] 2024 Oct 03; Vol. 84 (19), pp. 3667-3680. Date of Electronic Publication: 2024 Aug 14.Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

RNA binding protein with multiple splicing (RBPMS) promotes contractile phenotype splicing in human embryonic stem cell-derived vascular smooth muscle cells.

  • Authors : Jacob AG; Department of Biochemistry, University of Cambridge, Cambridge CB2 1QW, UK.; MRC-Wellcome Cambridge Stem Cell Institute, Cambridge CB2 0AW, UK.

Subjects: Human Embryonic Stem Cells*/Human Embryonic Stem Cells*/Human Embryonic Stem Cells*/metabolism ; Muscle, Smooth, Vascular*/Muscle, Smooth, Vascular*/Muscle, Smooth, Vascular*/metabolism ; Myocytes, Smooth Muscle*/Myocytes, Smooth Muscle*/Myocytes, Smooth Muscle*/metabolism

  • Source: Cardiovascular research [Cardiovasc Res] 2024 Dec 14; Vol. 120 (16), pp. 2104-2116.Publisher: Oxford Journals Country of Publication: England NLM ID: 0077427 Publication Model: Print Cited Medium: Internet ISSN: 1755-3245

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Academic Journal

Cancer-associated SF3B1 mutations inhibit mRNA nuclear export by disrupting SF3B1-THOC5 interactions.

  • Authors : Liu G; China-Japan Union Hospital of Jilin University, No. 126, Xiantai Street, Changchun, Jilin 130033, China.; Zhao B

Subjects: RNA Splicing Factors*/RNA Splicing Factors*/RNA Splicing Factors*/metabolism ; RNA Splicing Factors*/RNA Splicing Factors*/RNA Splicing Factors*/genetics ; RNA, Messenger*/RNA, Messenger*/RNA, Messenger*/genetics

  • Source: Journal of biochemistry [J Biochem] 2024 Dec 02; Vol. 176 (6), pp. 437-448.Publisher: Oxford University Press Country of Publication: England NLM ID: 0376600 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

The splicing factor SF3B1 is essential for proper alternative splicing and zygotic genome activation in early porcine embryos.

  • Authors : Zhao Y; College of Animal Science & Technology, Guangxi University, Nanning, Guangxi 530004, China; Guangxi Key Laboratory of Animal Breeding & Disease Control and Prevention, Guangxi University, Nanning, Guangxi 530004, China.

Subjects: Alternative Splicing* ; RNA Splicing Factors*/RNA Splicing Factors*/RNA Splicing Factors*/metabolism ; RNA Splicing Factors*/RNA Splicing Factors*/RNA Splicing Factors*/genetics

  • Source: International journal of biological macromolecules [Int J Biol Macromol] 2024 Dec; Vol. 282 (Pt 6), pp. 137401. Date of Electronic Publication: 2024 Nov 07.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Long-read transcriptome sequencing of CLL and MDS patients uncovers molecular effects of SF3B1 mutations.

  • Authors : Pacholewska A; Institute for Translational Epigenetics, Faculty of Medicine, University of Cologne, 50931 Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine, University of Cologne, 50931 Cologne, Germany.

Subjects: RNA Splicing Factors*/RNA Splicing Factors*/RNA Splicing Factors*/genetics ; RNA Splicing Factors*/RNA Splicing Factors*/RNA Splicing Factors*/metabolism ; Leukemia, Lymphocytic, Chronic, B-Cell*/Leukemia, Lymphocytic, Chronic, B-Cell*/Leukemia, Lymphocytic, Chronic, B-Cell*/genetics

  • Source: Genome research [Genome Res] 2024 Nov 20; Vol. 34 (11), pp. 1832-1848. Date of Electronic Publication: 2024 Nov 20.Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 9518021 Publication Model: Electronic Cited Medium:

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Academic Journal

Pharmacological Inhibition of the Spliceosome SF3b Complex by Pladienolide-B Elicits Craniofacial Developmental Defects in Mouse and Zebrafish.

  • Authors : Hoshino Y; Department of Molecular Craniofacial Embryology and Oral Histology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.; Office of Vaccines, Pharmaceuticals and Medical Devices Agency (PMDA), Japan.

Subjects: Zebrafish*/Zebrafish*/Zebrafish*/embryology ; Spliceosomes*/Spliceosomes*/Spliceosomes*/metabolism ; Spliceosomes*/Spliceosomes*/Spliceosomes*/drug effects

  • Source: Birth defects research [Birth Defects Res] 2024 Nov; Vol. 116 (11), pp. e2404.Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101701004 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

SF3B4 Regulates Cellular Senescence and Suppresses Therapy-induced Senescence of Cancer Cells.

  • Authors : Yang S; Department of Biochemistry, Institute for Aging and Metabolic Diseases, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.; Department of Medical Sciences, Graduate School of The Catholic University of Korea, Seoul, Republic of Korea.

Subjects: Cellular Senescence*/Cellular Senescence*/Cellular Senescence*/drug effects ; RNA Splicing Factors*/RNA Splicing Factors*/RNA Splicing Factors*/metabolism ; RNA Splicing Factors*/RNA Splicing Factors*/RNA Splicing Factors*/genetics

  • Source: Cancer genomics & proteomics [Cancer Genomics Proteomics] 2024 Nov-Dec; Vol. 21 (6), pp. 622-629.Publisher: International Institute of Anticancer Research Country of Publication: Greece NLM ID: 101188791 Publication Model: Print Cited Medium:

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Academic Journal

Alternative splicing of PBRM1 mediates resistance to PD-1 blockade therapy in renal cancer.

  • Authors : Cho N; Department of Biochemistry, College of Natural Sciences, Chungnam National University, Daejeon, 34134, Republic of Korea.; Kim SY

Subjects: Kidney Neoplasms*/Kidney Neoplasms*/Kidney Neoplasms*/genetics ; Kidney Neoplasms*/Kidney Neoplasms*/Kidney Neoplasms*/drug therapy ; Kidney Neoplasms*/Kidney Neoplasms*/Kidney Neoplasms*/metabolism

  • Source: The EMBO journal [EMBO J] 2024 Nov; Vol. 43 (22), pp. 5421-5444. Date of Electronic Publication: 2024 Oct 07.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The Arabidopsis splicing factor PORCUPINE/SmE1 orchestrates temperature-dependent root development via auxin homeostasis maintenance.

  • Authors : El Arbi N; Department of Plant Physiology, Umeå Plant Science Centre, Umeå University, SE-901 87, Umeå, Sweden.; Nardeli SM

Subjects: Arabidopsis*/Arabidopsis*/Arabidopsis*/genetics ; Arabidopsis*/Arabidopsis*/Arabidopsis*/growth & development ; Arabidopsis*/Arabidopsis*/Arabidopsis*/metabolism

  • Source: The New phytologist [New Phytol] 2024 Nov; Vol. 244 (4), pp. 1408-1421. Date of Electronic Publication: 2024 Sep 27.Publisher: Wiley on behalf of New Phytologist Trust Country of Publication: England NLM ID: 9882884 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

The non-canonical BAF chromatin remodeling complex is a novel target of spliceosome dysregulation in SF3B1-mutated chronic lymphocytic leukemia.

  • Authors : Hägerstrand D; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.; Oder B

Subjects: Leukemia, Lymphocytic, Chronic, B-Cell*/Leukemia, Lymphocytic, Chronic, B-Cell*/Leukemia, Lymphocytic, Chronic, B-Cell*/genetics ; Leukemia, Lymphocytic, Chronic, B-Cell*/Leukemia, Lymphocytic, Chronic, B-Cell*/Leukemia, Lymphocytic, Chronic, B-Cell*/pathology ; Leukemia, Lymphocytic, Chronic, B-Cell*/Leukemia, Lymphocytic, Chronic, B-Cell*/Leukemia, Lymphocytic, Chronic, B-Cell*/metabolism

  • Source: Leukemia [Leukemia] 2024 Nov; Vol. 38 (11), pp. 2429-2442. Date of Electronic Publication: 2024 Sep 11.Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium:

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  • 1-10 of  5,198 results for ""RNA Splicing Factors""