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Academic Journal

NEDD4L Suppresses Proliferation and Promotes Apoptosis by Ubiquitinating RAC2 Expression and Acts as a Prognostic Biomarker in Clear Cell Renal Cell Carcinoma.

  • Authors : Qi M; Department of Clinical Genetics, The Affiliated Shengjing Hospital, China Medical University, Shenyang 110004, China.; Tu J

Subjects: Carcinoma, Renal Cell*/Carcinoma, Renal Cell*/Carcinoma, Renal Cell*/metabolism ; Carcinoma, Renal Cell*/Carcinoma, Renal Cell*/Carcinoma, Renal Cell*/pathology ; Carcinoma, Renal Cell*/Carcinoma, Renal Cell*/Carcinoma, Renal Cell*/genetics

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Nov 06; Vol. 25 (22). Date of Electronic Publication: 2024 Nov 06.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

RAC2 gain-of-function variants causing inborn error of immunity drive NLRP3 inflammasome activation.

Subjects: NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/genetics ; NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism ; Inflammasomes*/Inflammasomes*/Inflammasomes*/metabolism

  • Source: The Journal of experimental medicine [J Exp Med] 2024 Oct 07; Vol. 221 (10). Date of Electronic Publication: 2024 Aug 30.Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985109R Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Identification of Cellular Isoschaftoside-Mediated Anti-Senescence Mechanism in RAC2 and LINC00294 .

  • Authors : Lee YH; Division of Life Sciences, College of Life Sciences and Bioengineering, Incheon National University, Incheon 22012, Republic of Korea.; So BH

Subjects: Cellular Senescence*/Cellular Senescence*/Cellular Senescence*/drug effects ; Reactive Oxygen Species*/Reactive Oxygen Species*/Reactive Oxygen Species*/metabolism ; rac GTP-Binding Proteins*/rac GTP-Binding Proteins*/rac GTP-Binding Proteins*/metabolism

  • Source: Molecules (Basel, Switzerland) [Molecules] 2024 Sep 04; Vol. 29 (17). Date of Electronic Publication: 2024 Sep 04.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

GDNF-induced phosphorylation of MUC21 promotes pancreatic cancer perineural invasion and metastasis by activating RAC2 GTPase.

  • Authors : Chen Y; Cancer Center of the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, 519000, Guangdong Province, China.; Guangdong Provincial Engineering Research Center of Molecular Imaging, the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, China.

Subjects: Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/pathology ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/metabolism ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/genetics

  • Source: Oncogene [Oncogene] 2024 Aug; Vol. 43 (34), pp. 2564-2577. Date of Electronic Publication: 2024 Jul 17.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Neutrophil-specific interactome of ARHGAP25 reveals novel partners and regulatory insights.

Subjects: GTPase-Activating Proteins*/GTPase-Activating Proteins*/GTPase-Activating Proteins*/metabolism ; Neutrophils*/Neutrophils*/Neutrophils*/metabolism ; Protein Binding*

  • Source: Scientific reports [Sci Rep] 2024 Aug 29; Vol. 14 (1), pp. 20106. Date of Electronic Publication: 2024 Aug 29.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Clinical and functional spectrum of RAC2-related immunodeficiency.

  • Authors : Donkó Á; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD.; Sharapova SO

Subjects: Immunologic Deficiency Syndromes*/Immunologic Deficiency Syndromes*/Immunologic Deficiency Syndromes*/genetics ; Immunologic Deficiency Syndromes*/Immunologic Deficiency Syndromes*/Immunologic Deficiency Syndromes*/metabolism ; Leukocyte-Adhesion Deficiency Syndrome* Leukocyte adhesion deficiency type 1

  • Source: Blood [Blood] 2024 Apr 11; Vol. 143 (15), pp. 1476-1487.Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020

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Academic Journal

Rac2 regulates immune complex-mediated granule polarization and exocytosis in neutrophils.

  • Authors : Ilarraza R; Department of Medicine, University of Alberta, 559 HMRC, Edmonton, Alberta T6G 2R3, Canada.; Chao DV

Subjects: Antigen-Antibody Complex*/Antigen-Antibody Complex*/Antigen-Antibody Complex*/metabolism ; Neutrophils*/Neutrophils*/Neutrophils*/metabolism; Animals

  • Source: Journal of leukocyte biology [J Leukoc Biol] 2023 Jul 27; Vol. 114 (2), pp. 116-125.Publisher: Oxford University Press Country of Publication: England NLM ID: 8405628 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Not too little, not too much: the impact of mutation types in Wiskott-Aldrich syndrome and RAC2 patients.

  • Authors : Hsu AP; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

Subjects: Thrombocytopenia*/Thrombocytopenia*/Thrombocytopenia*/genetics ; Wiskott-Aldrich Syndrome*/Wiskott-Aldrich Syndrome*/Wiskott-Aldrich Syndrome*/genetics ; Wiskott-Aldrich Syndrome*/Wiskott-Aldrich Syndrome*/Wiskott-Aldrich Syndrome*/metabolism

  • Source: Clinical and experimental immunology [Clin Exp Immunol] 2023 Apr 25; Vol. 212 (2), pp. 137-146.Publisher: Oxford University Press Country of Publication: England NLM ID: 0057202 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Novel Loss of Function (G15D) Mutation on RAC2 in a Family with Combined Immunodeficiency and Increased Levels of Immunoglobulin G, A, and E.

  • Authors : Duan X; Hunan Children's Hospital & School of Pediatrics, Hengyang Medical School, University of South China, Hunan, 421001, China.; Shen F

Subjects: Immunoglobulin G* ; Primary Immunodeficiency Diseases*; Animals

  • Source: Journal of clinical immunology [J Clin Immunol] 2023 Apr; Vol. 43 (3), pp. 604-614. Date of Electronic Publication: 2022 Dec 02.Publisher: Springer Country of Publication: Netherlands NLM ID: 8102137 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

HIF-1α promotes paraquat induced acute lung injury and implicates a role NF-κB and Rac2 activity.

  • Authors : Zhu Y; Department of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai 201620, China.; Meng X

Subjects: Acute Lung Injury*/Acute Lung Injury*/Acute Lung Injury*/chemically induced ; Acute Lung Injury*/Acute Lung Injury*/Acute Lung Injury*/metabolism ; Hypoxia-Inducible Factor 1, alpha Subunit*/Hypoxia-Inducible Factor 1, alpha Subunit*/Hypoxia-Inducible Factor 1, alpha Subunit*/drug effects

  • Source: Toxicology [Toxicology] 2023 Jan 01; Vol. 483, pp. 153388. Date of Electronic Publication: 2022 Nov 30.Publisher: Elsevier Country of Publication: Ireland NLM ID: 0361055 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3185

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  • 1-10 of  344 results for ""RAC2 GTP-Binding Protein""