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Academic Journal

The pyruvate dehydrogenase complex at the epigenetic crossroads of acetylation and lactylation.

  • Authors : Stacpoole PW; University of Florida, College of Medicine Department of Medicine, Department of Biochemistry & Molecular Biology, Gainesville, FL, United States. Electronic address: .; Dirain CO

Subjects: Pyruvate Dehydrogenase Complex*/Pyruvate Dehydrogenase Complex*/Pyruvate Dehydrogenase Complex*/metabolism ; Pyruvate Dehydrogenase Complex*/Pyruvate Dehydrogenase Complex*/Pyruvate Dehydrogenase Complex*/genetics ; Epigenesis, Genetic*

  • Source: Molecular genetics and metabolism [Mol Genet Metab] 2024 Sep-Oct; Vol. 143 (1-2), pp. 108540. Date of Electronic Publication: 2024 Jul 16.Publisher: Academic Press Country of Publication: United States NLM ID: 9805456 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Nuclear pyruvate dehydrogenase complex regulates histone acetylation and transcriptional regulation in the ethylene response.

  • Authors : Shao Z; Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, TX 78712, USA.; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712, USA.

Subjects: Ethylenes*/Ethylenes*/Ethylenes*/metabolism ; Gene Expression Regulation, Plant* ; Pyruvate Dehydrogenase Complex*/Pyruvate Dehydrogenase Complex*/Pyruvate Dehydrogenase Complex*/metabolism

  • Source: Science advances [Sci Adv] 2024 Jul 26; Vol. 10 (30), pp. eado2825. Date of Electronic Publication: 2024 Jul 26.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic

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Academic Journal

Stoichiometry and architecture of the human pyruvate dehydrogenase complex.

  • Authors : Zdanowicz R; Department of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, Otto-Stern-Weg 5, 8093 Zürich, Switzerland.; Afanasyev P

Subjects: Pyruvate Dehydrogenase Complex*/Pyruvate Dehydrogenase Complex*/Pyruvate Dehydrogenase Complex*/metabolism ; Pyruvate Dehydrogenase Complex*/Pyruvate Dehydrogenase Complex*/Pyruvate Dehydrogenase Complex*/chemistry ; Cryoelectron Microscopy*

  • Source: Science advances [Sci Adv] 2024 Jul 19; Vol. 10 (29), pp. eadn4582. Date of Electronic Publication: 2024 Jul 17.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic

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Academic Journal

Manifestations of X-linked pyruvate dehydrogenase complex deficiency in female PDHA1 carriers.

  • Authors : Savvidou A; Department of Pediatrics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Pediatrics, Queen Silvia Children's Hospital, Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden.

Subjects: Pyruvate Dehydrogenase (Lipoamide)*/Pyruvate Dehydrogenase (Lipoamide)*/Pyruvate Dehydrogenase (Lipoamide)*/genetics ; Pyruvate Dehydrogenase Complex Deficiency Disease*/Pyruvate Dehydrogenase Complex Deficiency Disease*/Pyruvate Dehydrogenase Complex Deficiency Disease*/genetics ; Heterozygote*

  • Source: European journal of neurology [Eur J Neurol] 2024 Jul; Vol. 31 (7), pp. e16283. Date of Electronic Publication: 2024 Mar 18.Publisher: Wiley Country of Publication: England NLM ID: 9506311 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-1331

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Metabolic stroke-like events in a girl with pyruvate dehydrogenase complex deficiency caused by a novel de novo mutation in PDHA1.

  • Authors : Fecarotta S; Metabolic Unit, Department of Translational Medical Sciences, University of Naples Federico II, Naples, Italy. .; D'Amico A

Subjects: Mutation* ; Pyruvate Dehydrogenase (Lipoamide)*/Pyruvate Dehydrogenase (Lipoamide)*/Pyruvate Dehydrogenase (Lipoamide)*/genetics ; Pyruvate Dehydrogenase Complex Deficiency Disease*/Pyruvate Dehydrogenase Complex Deficiency Disease*/Pyruvate Dehydrogenase Complex Deficiency Disease*/genetics

  • Source: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology [Neurol Sci] 2024 Jun; Vol. 45 (6), pp. 2913-2914. Publisher: Springer-Verlag Italia Country of Publication: Italy NLM ID: 100959175 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Dimerization of a 5-kDa domain defines the architecture of the 5-MDa gammaproteobacterial pyruvate dehydrogenase complex.

  • Authors : Meinhold S; ETH Zürich, Institute of Molecular Biology and Biophysics, Otto-Stern-Weg 5, 8093 Zürich, Switzerland.; Zdanowicz R

Subjects: Dihydrolipoamide Dehydrogenase*/Dihydrolipoamide Dehydrogenase*/Dihydrolipoamide Dehydrogenase*/genetics ; Dihydrolipoamide Dehydrogenase*/Dihydrolipoamide Dehydrogenase*/Dihydrolipoamide Dehydrogenase*/chemistry ; Dihydrolipoamide Dehydrogenase*/Dihydrolipoamide Dehydrogenase*/Dihydrolipoamide Dehydrogenase*/metabolism

  • Source: Science advances [Sci Adv] 2024 Feb 09; Vol. 10 (6), pp. eadj6358. Date of Electronic Publication: 2024 Feb 07.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic

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Academic Journal

Regulating the metabolic flux of pyruvate dehydrogenase bypass to enhance lipid production in Saccharomyces cerevisiae.

  • Authors : Lei C; Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China.; University of Chinese Academy of Sciences, Beijing, China.

Subjects: Saccharomyces cerevisiae*/Saccharomyces cerevisiae*/Saccharomyces cerevisiae*/genetics ; Saccharomyces cerevisiae*/Saccharomyces cerevisiae*/Saccharomyces cerevisiae*/metabolism ; Pyruvate Dehydrogenase Complex*/Pyruvate Dehydrogenase Complex*/Pyruvate Dehydrogenase Complex*/metabolism

  • Source: Communications biology [Commun Biol] 2024 Oct 26; Vol. 7 (1), pp. 1399. Date of Electronic Publication: 2024 Oct 26.Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Targeting the pyruvate dehydrogenase complex/pyruvate dehydrogenase kinase (PDC/PDK) axis to discover potent PDK inhibitors through structure-based virtual screening and pharmacological evaluation.

  • Authors : Gan L; Chongqing Engineering Research Center of Pharmaceutical Sciences, School of Pharmacy, Chongqing Medical and Pharmaceutical College, Chongqing, 401331, PR China.; Yang Y

Subjects: Protein Serine-Threonine Kinases* ; Pyruvate Dehydrogenase Complex*/Pyruvate Dehydrogenase Complex*/Pyruvate Dehydrogenase Complex*/metabolism; Pyruvate Dehydrogenase Acetyl-Transferring Kinase/Pyruvate Dehydrogenase Acetyl-Transferring Kinase/Pyruvate Dehydrogenase Acetyl-Transferring Kinase/metabolism

  • Source: European journal of medicinal chemistry [Eur J Med Chem] 2024 Jan 15; Vol. 264, pp. 116008. Date of Electronic Publication: 2023 Dec 03.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Trans -Cinnamaldehyde Inhibition of Pyruvate Dehydrogenase: Effects on Streptococcus mutans Carbohydrate Metabolism.

  • Authors : Zhang H; School of Biological Engineering, Zhuhai Campus of Zunyi Medical University, Guangdong 519041, China.; Mu R

Subjects: Streptococcus mutans*/Streptococcus mutans*/Streptococcus mutans*/drug effects ; Streptococcus mutans*/Streptococcus mutans*/Streptococcus mutans*/genetics ; Streptococcus mutans*/Streptococcus mutans*/Streptococcus mutans*/enzymology

  • Source: Journal of proteome research [J Proteome Res] 2024 Aug 02; Vol. 23 (8), pp. 3682-3695. Date of Electronic Publication: 2024 Jul 22.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101128775 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Regulation of muscle pyruvate dehydrogenase activity and fuel use during exercise in high-altitude deer mice.

  • Authors : Coulson SZ; Department of Biology, McMaster University, 1280 Main Street West, Hamilton, ON, Canada, L8S 4K1.; Lyons SA

Subjects: Altitude* ; Muscle, Skeletal*/Muscle, Skeletal*/Muscle, Skeletal*/metabolism ; Muscle, Skeletal*/Muscle, Skeletal*/Muscle, Skeletal*/enzymology

  • Source: The Journal of experimental biology [J Exp Biol] 2024 Aug 15; Vol. 227 (16). Date of Electronic Publication: 2024 Aug 20.Publisher: Company Of Biologists Limited Country of Publication: England NLM ID: 0243705 Publication Model: Print-Electronic Cited Medium: Internet

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  • 1-10 of  32,932 results for ""Pyruvate Dehydrogenase Complex""