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  • 1-10 of  59,313 results for ""Proto-Oncogene Proteins c-akt""

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Academic Journal

Anti-TL1A monoclonal antibody modulates the dysregulation of Th1/Th17 cells and attenuates granuloma formation in sarcoidosis by inhibiting the PI3K/AKT signaling pathway.

  • Authors : Ma C; Department of Respiratory and Critical Care Medicine, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.; Huang J

Subjects: Th1 Cells*/Th1 Cells*/Th1 Cells*/immunology ; Th17 Cells*/Th17 Cells*/Th17 Cells*/immunology ; Signal Transduction*/Signal Transduction*/Signal Transduction*/drug effects

  • Source: International immunopharmacology [Int Immunopharmacol] 2024 Aug 20; Vol. 137, pp. 112360. Date of Electronic Publication: 2024 Jun 08.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Ac-HSP20 regulates autophagy and promotes the encystation of Acanthamoeba castellanii by inhibiting the PI3K/AKT/mTOR signaling pathway.

  • Authors : Guo S; Department of Pathogenic Biology, Jilin Medical University, Jilin, China.; Department of Clinical Laboratory, Jilin City Hospital of Chemical Industry, Jilin, China.

Subjects: Autophagy* ; TOR Serine-Threonine Kinases*/TOR Serine-Threonine Kinases*/TOR Serine-Threonine Kinases*/metabolism ; TOR Serine-Threonine Kinases*/TOR Serine-Threonine Kinases*/TOR Serine-Threonine Kinases*/genetics

  • Source: Parasites & vectors [Parasit Vectors] 2024 Aug 19; Vol. 17 (1), pp. 347. Date of Electronic Publication: 2024 Aug 19.Publisher: BioMed Central Country of Publication: England NLM ID: 101462774 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-3305

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Academic Journal

Mesenchymal stem cells-derived exosomes alleviate senescence of retinal pigment epithelial cells by activating PI3K/AKT-Nrf2 signaling pathway in early diabetic retinopathy.

  • Authors : Bai L; Aier Academy of Ophthalmology, Central South University, Changsha, Hunan, PR China.; Wang Y

Subjects: Diabetic Retinopathy*/Diabetic Retinopathy*/Diabetic Retinopathy*/metabolism ; Diabetic Retinopathy*/Diabetic Retinopathy*/Diabetic Retinopathy*/pathology ; Diabetic Retinopathy*/Diabetic Retinopathy*/Diabetic Retinopathy*/genetics

  • Source: Experimental cell research [Exp Cell Res] 2024 Aug 15; Vol. 441 (2), pp. 114170. Date of Electronic Publication: 2024 Jul 15.Publisher: Academic Press Country of Publication: United States NLM ID: 0373226 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Protective function of albiflorin against ferroptosis in exhaustive exerciseinduced myocardial injury via the AKT/Nrf2/HO-1 signaling.

  • Authors : Tian Z; Zhengzhou University - College of Physical Education - Zhengzhou, Henan Province, China.; Jeonbuk National University - College of Natural Science - Department of Sport Science - Jeonju, South Korea.

Subjects: NF-E2-Related Factor 2*/NF-E2-Related Factor 2*/NF-E2-Related Factor 2*/metabolism ; Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/metabolism ; Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/drug effects

  • Source: Acta cirurgica brasileira [Acta Cir Bras] 2024 Aug 12; Vol. 39, pp. e393524. Date of Electronic Publication: 2024 Aug 12 (Print Publication: 2024).Publisher: Sociedade Brasileira Para O Desenvolvimento Da Pesquisa Em Cirurgia Curso De Pos-Graduacao Em Tecnica Operatoria E Cirurgia Experimental Escola Paulista De Medicina

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Academic Journal

Impact of microRNA variants on PI3K/AKT signaling in triple-negative breast cancer: comprehensive review.

  • Authors : Mehrtabar E; Advanced Diagnostic and Interventional Radiology Research Center (ADIR), Tehran University of Medical Sciences, Tehran, Iran.; Khalaji A

Subjects: Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/genetics ; Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/metabolism ; Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/pathology

  • Source: Medical oncology (Northwood, London, England) [Med Oncol] 2024 Aug 09; Vol. 41 (9), pp. 222. Date of Electronic Publication: 2024 Aug 09.Publisher: Springer Country of Publication: United States NLM ID: 9435512 Publication Model: Electronic Cited Medium: Internet ISSN: 1559-131X

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Academic Journal

Sinomenine Alleviates Rheumatoid Arthritis by Suppressing the PI3K-Akt Signaling Pathway, as Demonstrated Through Network Pharmacology, Molecular Docking, and Experimental Validation.

  • Authors : Liu Q; Department of Clinical Laboratory, Wuxi Ninth People's Hospital Affiliated to Soochow University, Wuxi, Jiangsu, 214000, People's Republic of China.; Wang J

Subjects: Morphinans*/Morphinans*/Morphinans*/pharmacology ; Morphinans*/Morphinans*/Morphinans*/chemistry ; Arthritis, Rheumatoid*/Arthritis, Rheumatoid*/Arthritis, Rheumatoid*/drug therapy

  • Source: Drug design, development and therapy [Drug Des Devel Ther] 2024 Aug 06; Vol. 18, pp. 3523-3545. Date of Electronic Publication: 2024 Aug 06 (Print Publication: 2024).Publisher: Dove Press Limited Country of Publication: New Zealand NLM ID: 101475745 Publication Model: eCollection Cited Medium: Internet ISSN:

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Academic Journal

Association between MAPK and PI3K/Akt signaling pathway-related gene polymorphisms and migraine.

  • Authors : Wang M; Department of Epidemiology, School of Public Health, Harbin Medical University, Harbin, China.; Gu Y

Subjects: Migraine Disorders*/Migraine Disorders*/Migraine Disorders*/genetics ; Polymorphism, Single Nucleotide* ; Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/genetics

  • Source: Molecular genetics & genomic medicine [Mol Genet Genomic Med] 2024 Aug; Vol. 12 (8), pp. e2503.Publisher: John Wiley & Sons Country of Publication: United States NLM ID: 101603758 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

BI-7273, a BRD9 inhibitor, reduces lipid accumulation by downregulating the AKT/mTOR/SREBP1 signaling pathway.

  • Authors : Li Y; Laboratory of Gene Therapy, Department of Biochemistry, College of Life Sciences, Shaanxi Normal University, 199 South Chang'an Road, Xi'an 710062, Shaanxi, PR China.; He Q

Subjects: Lipid Metabolism*/Lipid Metabolism*/Lipid Metabolism*/drug effects ; Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/metabolism ; Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/antagonists & inhibitors

  • Source: Biochemical pharmacology [Biochem Pharmacol] 2024 Aug; Vol. 226, pp. 116412. Date of Electronic Publication: 2024 Jul 05.Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Paediatric strategy forum for medicinal product development of PI3-K, mTOR, AKT and GSK3β inhibitors in children and adolescents with cancer.

Subjects: Neoplasms*/Neoplasms*/Neoplasms*/drug therapy ; Neoplasms*/Neoplasms*/Neoplasms*/genetics ; Glycogen Synthase Kinase 3 beta*/Glycogen Synthase Kinase 3 beta*/Glycogen Synthase Kinase 3 beta*/antagonists & inhibitors

  • Source: European journal of cancer (Oxford, England : 1990) [Eur J Cancer] 2024 Aug; Vol. 207, pp. 114145. Date of Electronic Publication: 2024 Jun 08.Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9005373 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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A novel TCF3::PIK3R1 fusion linked to decreased PI3K-AKT signalling activity in paediatric B-acute lymphoblastic leukaemia.

  • Authors : Grady E; Systems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland.; Biswas S

Subjects: Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/metabolism ; Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/genetics ; Signal Transduction*

  • Source: British journal of haematology [Br J Haematol] 2024 Aug; Vol. 205 (2), pp. 738-741. Date of Electronic Publication: 2024 Jun 14.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 0372544 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  59,313 results for ""Proto-Oncogene Proteins c-akt""