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Academic Journal

Cure of Congenital Purpura Fulminans via Expression of Engineered Protein C Through Neonatal Genome Editing in Mice.

  • Authors : Togashi T; Department of Clinical Laboratory Science, Division of Health Sciences, Graduate School of Medical Science, Kanazawa University, Ishikawa, Japan (T.T., E.M.).; Department of Biochemistry, Jichi Medical University School of Medicine, Tochigi, Japan (T.T., N.B., Y.K., M.H., T.H., T.O.).

Subjects: Protein C*/Protein C*/Protein C*/metabolism ; Protein C*/Protein C*/Protein C*/genetics ; Gene Editing*/Gene Editing*/Gene Editing*/methods

  • Source: Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2024 Dec; Vol. 44 (12), pp. 2616-2627. Date of Electronic Publication: 2024 Nov 07.Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9505803 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Specific DNA aptamer-immobilized cryogel membranes as novel bioaffinity supports and their potential for the purification of activated protein C.

Subjects: Cryogels*/Cryogels*/Cryogels*/chemistry ; Protein C*/Protein C*/Protein C*/chemistry ; Protein C*/Protein C*/Protein C*/isolation & purification

  • Source: Biomedical chromatography : BMC [Biomed Chromatogr] 2024 Nov; Vol. 38 (11), pp. e5995. Date of Electronic Publication: 2024 Aug 27.Publisher: Wiley Country of Publication: England NLM ID: 8610241 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1099-0801

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Academic Journal

[Molecular Mechanism of Protein C Deficiency Caused by Mutations of PROC Gene N355S, G392E, T314A].

  • Authors : Li TY; Jiangsu Institute of Hematology, National Clinical Research Center for Hematologic Diseases, NHC Key Laboratory of Thrombosis and Hemostasis, The First Affiliated Hospital of Soochow University, Collaborative Innovation Center of Hematology, Suzhou 215006, Jiangsu Province, China.; State Key Laboratory of Radiation Medicine and Protection, Soochow University, Suzhou 215123, Jiangsu Province, China.

Subjects: Protein C*/Protein C*/Protein C*/genetics ; Protein C*/Protein C*/Protein C*/metabolism ; Transfection*

  • Source: Zhongguo shi yan xue ye xue za zhi [Zhongguo Shi Yan Xue Ye Xue Za Zhi] 2024 Dec; Vol. 32 (6), pp. 1834-1840.Publisher: Zhongguo shi yan xue za zhi she Country of Publication: China NLM ID: 101084424 Publication Model: Print Cited Medium: Print ISSN:

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Academic Journal

Cytoprotective 3K3A-activated protein C and plasma: A comparison of therapeutics for the endotheliopathy of trauma.

  • Authors : Thielen O; From the University of Colorado, Department of Surgery, Division Gastrointestinal, Trauma, and Endocrine Surgery, Aurora, CO (O.T., P.S., M.D., M.K., S.M., W.H., L.T.G., T.S., B.S., B.R., A.D., K.H., C.C.S., E.M., M.C.); The Ernest E Moore Shock Trauma Center at Denver Health, Denver Health Medical Center, Department of Surgery, Denver, CO (E.M.)

Subjects: Wounds and Injuries*/Wounds and Injuries*/Wounds and Injuries*/complications ; Wounds and Injuries*/Wounds and Injuries*/Wounds and Injuries*/therapy ; Protein C*/Protein C*/Protein C*/therapeutic use

  • Source: The journal of trauma and acute care surgery [J Trauma Acute Care Surg] 2025 Jan 01; Vol. 98 (1), pp. 94-100. Date of Electronic Publication: 2024 May 27.Publisher: Lippincott, Williams & Wilkins Country of Publication: United States NLM ID: 101570622 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Assessment of Hypercoagulability in Splanchnic Vein Thrombosis by Measurement of the Hemostasis Enzymes Thrombin and Activated Protein C.

  • Authors : Reda S; Institute of Experimental Hematology and Transfusion Medicine, University Hospital Bonn, 53127 Bonn, Germany.; Department of Transfusion Medicine, University Hospital Cologne, 50937 Cologne, Germany.

Subjects: Protein C*/Protein C*/Protein C*/metabolism ; Venous Thrombosis*/Venous Thrombosis*/Venous Thrombosis*/blood ; Venous Thrombosis*/Venous Thrombosis*/Venous Thrombosis*/etiology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Dec 31; Vol. 26 (1). Date of Electronic Publication: 2024 Dec 31.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Divergent modulation of activated protein C pleiotropic functions by antibodies that differ by a single amino acid.

  • Authors : Sim DS; Coagulant Therapeutics Corporation, Berkeley, CA.; Shukla M

Subjects: Protein C*/Protein C*/Protein C*/metabolism; Humans ; Amino Acid Substitution

  • Source: Blood advances [Blood Adv] 2025 Jan 14; Vol. 9 (1), pp. 180-191.Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet

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Academic Journal

Protein C and S activities in COVID-19: A systematic review and meta-analysis.

  • Authors : Khoshnegah Z; Department of Hematology and Blood Banking, Faculty of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran.; Siyadat P

Subjects: COVID-19*/COVID-19*/COVID-19*/blood ; Protein C*/Protein C*/Protein C*/metabolism ; Protein S*/Protein S*/Protein S*/metabolism

  • Source: Journal of thrombosis and thrombolysis [J Thromb Thrombolysis] 2024 Aug; Vol. 57 (6), pp. 1018-1030. Date of Electronic Publication: 2024 May 09.Publisher: Kluwer Academic Publishers Country of Publication: Netherlands NLM ID: 9502018 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

An orthosteric/allosteric bivalent peptide agonist comprising covalently linked protease-activated receptor-derived peptides mimics in vitro and in vivo activities of activated protein C.

  • Authors : Healy LD; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, California, USA.; Fernández JA

Subjects: Protein C*/Protein C*/Protein C*/metabolism ; Protein C*/Protein C*/Protein C*/chemistry ; Receptor, PAR-1*/Receptor, PAR-1*/Receptor, PAR-1*/agonists

  • Source: Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2024 Jul; Vol. 22 (7), pp. 2039-2051. Date of Electronic Publication: 2024 Apr 24.Publisher: Elsevier Country of Publication: England NLM ID: 101170508 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7836

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Academic Journal

A Novel Murine Model Enabling rAAV8-PC Gene Therapy for Severe Protein C Deficiency.

  • Authors : Levy-Mendelovich S; National Hemophilia Center, Thrombosis & Hemostasis Institute, Sheba Medical Center, Ramat Gan 52621, Israel.; Amalia Biron Research Institute of Thrombosis & Hemostasis, Faculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv 6997801, Israel.

Subjects: Genetic Therapy*/Genetic Therapy*/Genetic Therapy*/methods ; Dependovirus*/Dependovirus*/Dependovirus*/genetics ; Disease Models, Animal*

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Sep 26; Vol. 25 (19). Date of Electronic Publication: 2024 Sep 26.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Met343Val mutation disrupts the shuttling of Trp380 leading to a low-activity conformer of activated protein C and causes thrombosis.

  • Authors : Zhou S; Department of Laboratory Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Li F

Subjects: Protein C*/Protein C*/Protein C*/metabolism ; Protein C*/Protein C*/Protein C*/genetics ; Thrombosis*/Thrombosis*/Thrombosis*/genetics

  • Source: Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2024 Aug; Vol. 22 (8), pp. 2270-2280. Date of Electronic Publication: 2024 May 23.Publisher: Elsevier Country of Publication: England NLM ID: 101170508 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7836

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  • 1-10 of  263,510 results for ""Protein C""