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Additional PfCRT mutations driven by selective pressure for improved fitness can result in the loss of piperaquine resistance and altered Plasmodium falciparum physiology.

• Authors : Hagenah LM; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, New York, USA.; Center for Malaria Therapeutics and Antimicrobial Resistance, Columbia University Irving Medical Center, New York, New York, USA.

Subjects: Quinolines*/Quinolines*/Quinolines*/pharmacology ; Quinolines*/Quinolines*/Quinolines*/chemistry ; Antimalarials*/Antimalarials*/Antimalarials*/pharmacology

• Source: MBio [mBio] 2024 Jan 16; Vol. 15 (1), pp. e0183223. Date of Electronic Publication: 2023 Dec 07.Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101519231 Publication Model: Print-Electronic Cited Medium:

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Findings from Columbia University Provides New Data about Malaria (Additional Pfcrt Mutations Driven By Selective Pressure for Improved Fitness Can Result In the Loss of Piperaquine Resistance and Altered plasmodium Falciparum Physiology).

Subjects: PLASMODIUM falciparum; MALARIA; PHYSIOLOGY

• Source: Zika & Mosquito Week; 1/12/2024, p323-323, 1p

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