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Academic Journal

Harnessing sulfur-binding domains to separate Sp and Rp isomers of phosphorothioate oligonucleotides.

  • Authors : Ge F; State Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic & Developmental Sciences, School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, 200240, People's Republic of China.; Wang Y

Subjects: Phosphorothioate Oligonucleotides*/Phosphorothioate Oligonucleotides*/Phosphorothioate Oligonucleotides*/chemistry ; Phosphorothioate Oligonucleotides*/Phosphorothioate Oligonucleotides*/Phosphorothioate Oligonucleotides*/metabolism ; Phosphorothioate Oligonucleotides*/Phosphorothioate Oligonucleotides*/Phosphorothioate Oligonucleotides*/isolation & purification

  • Source: Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2024 Aug 27; Vol. 108 (1), pp. 448. Date of Electronic Publication: 2024 Aug 27.Publisher: Springer International Country of Publication: Germany NLM ID: 8406612 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Improving dynamic control of toehold-mediated strand displacement reactions through phosphorothioate modifications.

  • Authors : Liang R; School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. .; Shen Y

Subjects: Phosphorothioate Oligonucleotides*/Phosphorothioate Oligonucleotides*/Phosphorothioate Oligonucleotides*/chemistry ; DNA*/DNA*/DNA*/chemistry

  • Source: Nanoscale [Nanoscale] 2024 Dec 12; Vol. 16 (48), pp. 22393-22402. Date of Electronic Publication: 2024 Dec 12.Publisher: RSC Pub Country of Publication: England NLM ID: 101525249 Publication Model: Electronic Cited Medium: Internet ISSN: 2040-3372

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Academic Journal

Effect of diastereoisomeric composition on the chromatographic retention of phosphorothioated oligonucleotides using three different liquid chromatography systems.

  • Authors : Roussis SG; Ionis Pharmaceuticals, 2855 Gazelle Ct., Carlsbad, California 92010, United States. Electronic address: .; Wan WB

Subjects: Phosphorothioate Oligonucleotides*/Phosphorothioate Oligonucleotides*/Phosphorothioate Oligonucleotides*/chemistry ; Phosphorothioate Oligonucleotides*/Phosphorothioate Oligonucleotides*/Phosphorothioate Oligonucleotides*/analysis; Stereoisomerism

  • Source: Journal of chromatography. A [J Chromatogr A] 2024 Aug 16; Vol. 1730, pp. 465108. Date of Electronic Publication: 2024 Jun 18.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9318488 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Two-dimensional sequential selective comprehensive chiral×reversed-phase liquid chromatography of synthetic phosphorothioate oligonucleotide diastereomers.

  • Authors : Li F; Institute of Pharmaceutical Sciences, Pharmaceutical (Bio-)Analysis, University of Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany.; Knappe C

Subjects: Phosphorothioate Oligonucleotides*/Phosphorothioate Oligonucleotides*/Phosphorothioate Oligonucleotides*/chemistry ; Chromatography, Reverse-Phase*/Chromatography, Reverse-Phase*/Chromatography, Reverse-Phase*/methods; Stereoisomerism

  • Source: Journal of chromatography. A [J Chromatogr A] 2024 Aug 16; Vol. 1730, pp. 465076. Date of Electronic Publication: 2024 Jun 11.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9318488 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Impact of ion-pairing systems choice on diastereomeric selectivity of phosphorothioated oligonucleotides in reversed-phase liquid chromatography.

  • Authors : Vosáhlová Z; Department of Physical and Macromolecular Chemistry, Faculty of Science, Charles University, Hlavova 8, Prague 12800, Czech Republic.; Gilar M

Subjects: Chromatography, Reverse-Phase*/Chromatography, Reverse-Phase*/Chromatography, Reverse-Phase*/methods ; Phosphorothioate Oligonucleotides*/Phosphorothioate Oligonucleotides*/Phosphorothioate Oligonucleotides*/chemistry ; Phosphorothioate Oligonucleotides*/Phosphorothioate Oligonucleotides*/Phosphorothioate Oligonucleotides*/isolation & purification

  • Source: Journal of chromatography. A [J Chromatogr A] 2024 Aug 16; Vol. 1730, pp. 465074. Date of Electronic Publication: 2024 Jun 10.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9318488 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Stereo-Controlled Liquid Phase Synthesis of Phosphorothioate Oligonucleotides on a Soluble Support.

  • Authors : Rosenqvist P; Department of Chemistry, University of Turku, 20500 Turku, Finland.; Saari V

Subjects: Phosphorothioate Oligonucleotides*/Phosphorothioate Oligonucleotides*/Phosphorothioate Oligonucleotides*/chemistry; Stereoisomerism

  • Source: The Journal of organic chemistry [J Org Chem] 2023 Jul 21; Vol. 88 (14), pp. 10156-10163. Date of Electronic Publication: 2023 Jul 10.Publisher: American Chemical Society Country of Publication: United States NLM ID: 2985193R Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Phosphorothioate oligonucleotides separation in ion-pairing reversed-phase liquid chromatography: effect of temperature.

  • Authors : Kadlecová Z; Department of Physical and Macromolecular Chemistry, Faculty of Science, Charles University, Hlavova 8, 12800, Prague, Czech Republic.; Kalíková K

Subjects: Chromatography, Reverse-Phase*/Chromatography, Reverse-Phase*/Chromatography, Reverse-Phase*/methods ; Phosphorothioate Oligonucleotides*; Temperature

  • Source: Journal of chromatography. A [J Chromatogr A] 2022 Oct 11; Vol. 1681, pp. 463473. Date of Electronic Publication: 2022 Sep 07.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9318488 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Hydrophilic interaction liquid chromatography with mass spectrometry for the separation and identification of antisense oligonucleotides impurities and nusinersen metabolites.

  • Authors : Vosáhlová Z; Department of Physical and Macromolecular Chemistry, Faculty of Science, Charles University, Hlavova 8, 12800, Prague, Czech Republic.; Kalíková K

Subjects: Oligonucleotides, Antisense* ; Phosphorothioate Oligonucleotides*; Humans

  • Source: Journal of chromatography. A [J Chromatogr A] 2024 Jan 04; Vol. 1713, pp. 464535. Date of Electronic Publication: 2023 Nov 26.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9318488 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Sequence- and Structure-Dependent Cytotoxicity of Phosphorothioate and 2'- O -Methyl Modified Single-Stranded Oligonucleotides.

  • Authors : Croft LV; School of Biomedical Sciences, Centre for Genomics and Personalised Health, Cancer and Ageing Research Program at Translational Research Institute, Faculty of Health, Queensland University of Technology, Brisbane, Australia.; Fisher M

Subjects: Phosphorothioate Oligonucleotides*/Phosphorothioate Oligonucleotides*/Phosphorothioate Oligonucleotides*/chemistry ; Phosphorothioate Oligonucleotides*/Phosphorothioate Oligonucleotides*/Phosphorothioate Oligonucleotides*/pharmacology ; Molecular Dynamics Simulation*

  • Source: Nucleic acid therapeutics [Nucleic Acid Ther] 2024; Vol. 34 (3), pp. 143-155. Date of Electronic Publication: 2024 Apr 22.Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 101562758 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Phosphorothioate oligonucleotides separation in ion-pairing reversed-phase liquid chromatography: Effect of ion-pairing system.

  • Authors : Kadlecová Z; Department of Physical and Macromolecular Chemistry, Faculty of Science, Charles University, Hlavova 8, 12800, Prague, Czech Republic.; Kalíková K

Subjects: Chromatography, Reverse-Phase*/Chromatography, Reverse-Phase*/Chromatography, Reverse-Phase*/methods ; Phosphorothioate Oligonucleotides*; Amines/Amines/Amines/chemistry

  • Source: Journal of chromatography. A [J Chromatogr A] 2022 Aug 02; Vol. 1676, pp. 463201. Date of Electronic Publication: 2022 Jun 07.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9318488 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  5,789 results for ""Phosphorothioate Oligonucleotides""