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Academic Journal

CD8 T cell-derived perforin regulates macrophage-mediated inflammation in a murine model of gout.

  • Authors : Wang T; Department of Rheumatology and Immunology, Beijing Friendship Hospital, Capital Medical University, 95th, Yongan Road, Beijing, 100050, China.; Zhang C

Subjects: CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/immunology ; Macrophages*/Macrophages*/Macrophages*/metabolism ; Macrophages*/Macrophages*/Macrophages*/immunology

  • Source: Clinical rheumatology [Clin Rheumatol] 2024 Jun; Vol. 43 (6), pp. 2027-2034. Date of Electronic Publication: 2024 Apr 16.Publisher: Springer Country of Publication: Germany NLM ID: 8211469 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1434-9949

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Academic Journal

Perforin 1 in Cancer: Mechanisms, Therapy, and Outlook.

  • Authors : Guan X; Shanxi Key Laboratory of Otorhinolaryngology Head and Neck Cancer, First Hospital of Shanxi Medical University, Taiyuan 030001, China.; Shanxi Province Clinical Medical Research Center for Precision Medicine of Head and Neck Cancer, First Hospital of Shanxi Medical University, Taiyuan 030001, China.

Subjects: Perforin*/Perforin*/Perforin*/metabolism ; Perforin*/Perforin*/Perforin*/genetics ; Neoplasms*/Neoplasms*/Neoplasms*/therapy

  • Source: Biomolecules [Biomolecules] 2024 Jul 26; Vol. 14 (8). Date of Electronic Publication: 2024 Jul 26.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

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Academic Journal

Identification and functional analysis of perforin 1 from largemouth bass (Micropterus salmoides).

  • Authors : Hu X; State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Ningbo University, Ningbo, 315211, China; Laboratory of Biochemistry and Molecular Biology, School of Marine Sciences, Ningbo University, Ningbo, 315211, China

Subjects: Bass*/Bass*/Bass*/immunology ; Bass*/Bass*/Bass*/genetics ; Fish Diseases*/Fish Diseases*/Fish Diseases*/immunology Nocardia seriolae

  • Source: Fish & shellfish immunology [Fish Shellfish Immunol] 2024 Jun; Vol. 149, pp. 109531. Date of Electronic Publication: 2024 Apr 09.Publisher: Academic Press Country of Publication: England NLM ID: 9505220 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Reassessing granzyme B: unveiling perforin-independent versatility in immune responses and therapeutic potentials.

  • Authors : Thompson R; Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland Baltimore School of Medicine, Baltimore, MD, United States.; Cao X

Subjects: Granzymes*/Granzymes*/Granzymes*/metabolism ; Perforin*/Perforin*/Perforin*/metabolism ; T-Lymphocytes, Cytotoxic*/T-Lymphocytes, Cytotoxic*/T-Lymphocytes, Cytotoxic*/immunology

  • Source: Frontiers in immunology [Front Immunol] 2024 May 23; Vol. 15, pp. 1392535. Date of Electronic Publication: 2024 May 23 (Print Publication: 2024).Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Sea Anemone Membrane Attack Complex/Perforin Superfamily Demonstrates an Evolutionary Transitional State between Venomous and Developmental Functions.

  • Authors : Surm JM; Department of Ecology, Evolution and Behavior, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, 9190401 Jerusalem, Israel.; Landau M

Subjects: Sea Anemones*/Sea Anemones*/Sea Anemones*/genetics ; Evolution, Molecular* ; Perforin*/Perforin*/Perforin*/metabolism

  • Source: Molecular biology and evolution [Mol Biol Evol] 2024 May 03; Vol. 41 (5).Publisher: Oxford University Press Country of Publication: United States NLM ID: 8501455 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Co-encapsulation of granzyme B and perforin in nanocapsules for tumour therapy: biomimicking immune cells.

  • Authors : Shi Z; Department of Medical Laboratory, School of Medical Technology, Tianjin Medical University, Tianjin 300203, China; The Third Department of Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin 300060, China.

Subjects: Granzymes*/Granzymes*/Granzymes*/metabolism ; Nanocapsules*/Nanocapsules*/Nanocapsules*/chemistry ; Perforin*/Perforin*/Perforin*/metabolism

  • Source: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2024 May; Vol. 369, pp. 658-667. Date of Electronic Publication: 2024 Apr 11.Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8607908 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Cordyceps sinensis extract protects against acute kidney injury by inhibiting perforin expression in NK cells via the STING/IRF3 pathway.

  • Authors : Li S; General Department of Western Medicine, Yangjing Community Health Service Center, Shanghai 200135, China.; Pang W

Subjects: Acute Kidney Injury*/Acute Kidney Injury*/Acute Kidney Injury*/metabolism ; Acute Kidney Injury*/Acute Kidney Injury*/Acute Kidney Injury*/drug therapy ; Acute Kidney Injury*/Acute Kidney Injury*/Acute Kidney Injury*/prevention & control

  • Source: Aging [Aging (Albany NY)] 2024 Mar 21; Vol. 16 (7), pp. 5887-5904. Date of Electronic Publication: 2024 Mar 21.Publisher: Impact Journals, LLC Country of Publication: United States NLM ID: 101508617 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Involvement of M1-Activated Macrophages and Perforin/Granulysin Expressing Lymphocytes in IgA Vasculitis Nephritis.

  • Authors : Laskarin G; Department of Physiology, Immunology and Pathophysiology, Faculty of Medicine, University of Rijeka, 51000 Rijeka, Croatia.; Hospital for Medical Rehabilitation of Hearth and Lung Diseases and Rheumatism 'Thalassotherapia-Opatija', 51410 Opatija, Croatia.

Subjects: IgA Vasculitis*/IgA Vasculitis*/IgA Vasculitis*/complications ; Killer Cells, Natural*/Killer Cells, Natural*/Killer Cells, Natural*/immunology ; Macrophages*/Macrophages*/Macrophages*/immunology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 13; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 13.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Peroxisome Proliferator-Activated Receptor δ Suppresses the Cytotoxicity of CD8+ T Cells by Inhibiting RelA DNA-Binding Activity.

  • Authors : Cen B; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, South Carolina.; Wei J

Subjects: Transcription Factor RelA*/Transcription Factor RelA*/Transcription Factor RelA*/metabolism ; Granzymes*/Granzymes*/Granzymes*/metabolism ; CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/immunology

  • Source: Cancer research communications [Cancer Res Commun] 2024 Oct 01; Vol. 4 (10), pp. 2673-2684.Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9918281580506676 Publication Model: Print Cited Medium:

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Academic Journal

Enrichment of Rare Variants of Hemophagocytic Lymphohistiocytosis Genes in Systemic Juvenile Idiopathic Arthritis.

Subjects: Lymphohistiocytosis, Hemophagocytic*/Lymphohistiocytosis, Hemophagocytic*/Lymphohistiocytosis, Hemophagocytic*/genetics ; Arthritis, Juvenile*/Arthritis, Juvenile*/Arthritis, Juvenile*/genetics ; Qa-SNARE Proteins*/Qa-SNARE Proteins*/Qa-SNARE Proteins*/genetics

  • Source: Arthritis & rheumatology (Hoboken, N.J.) [Arthritis Rheumatol] 2024 Oct; Vol. 76 (10), pp. 1566-1572. Date of Electronic Publication: 2024 Aug 09.Publisher: Wiley Country of Publication: United States NLM ID: 101623795 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  82,944 results for ""Perforin""