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Molecular Structure of the Na + ,K + -ATPase α4β1 Isoform in Its Ouabain-Bound Conformation.

• Authors : Abe K; Department of Chemistry, Faculty of Science, Hokkaido University, Hokkaido 060-0808, Japan.; McDermott J

Subjects: Sodium-Potassium-Exchanging ATPase*/Sodium-Potassium-Exchanging ATPase*/Sodium-Potassium-Exchanging ATPase*/metabolism ; Sodium-Potassium-Exchanging ATPase*/Sodium-Potassium-Exchanging ATPase*/Sodium-Potassium-Exchanging ATPase*/chemistry ; Ouabain*/Ouabain*/Ouabain*/metabolism

• Source: International journal of molecular sciences [Int J Mol Sci] 2024 Nov 19; Vol. 25 (22). Date of Electronic Publication: 2024 Nov 19.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Onset of bipolar disorder by COVID-19: The roles of endogenous ouabain and the Na,K-ATPase.

• Authors : Castro de Jesus L; Laboratory of Enzymology and Cell Signaling, Department of Cellular and Molecular Biology, Institute of Biology, Universidade Federal Fluminense, Niterói, RJ, 24020-141, Brazil. Electronic address: .; Gonçalves-de-Albuquerque CF

Subjects: Bipolar Disorder*/Bipolar Disorder*/Bipolar Disorder*/metabolism ; Bipolar Disorder*/Bipolar Disorder*/Bipolar Disorder*/physiopathology ; Ouabain*/Ouabain*/Ouabain*/metabolism

• Source: Journal of psychiatric research [J Psychiatr Res] 2024 Nov; Vol. 179, pp. 60-68. Date of Electronic Publication: 2024 Aug 31.Publisher: Pergamon Press Country of Publication: England NLM ID: 0376331 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Ouabain Ameliorates Alzheimer's Disease-Associated Neuropathology and Cognitive Impairment in FAD 4T Mice.

• Authors : Wang D; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230026, China.; Anhui Provincial Key Laboratory of Tumor Immunotherapy and Nutrition Therapy, Hefei 230001, China.

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/drug therapy ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism ; Cognitive Dysfunction*/Cognitive Dysfunction*/Cognitive Dysfunction*/drug therapy

• Source: Nutrients [Nutrients] 2024 Oct 20; Vol. 16 (20). Date of Electronic Publication: 2024 Oct 20.Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN:

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The cystogenic effects of ouabain in autosomal dominant polycystic kidney disease require cell caveolae.

• Authors : Trant J; Department of Cell Biology and Physiology and the Kidney Institute, University of Kansas Medical Center, Kansas City, KS, USA.; Sanchez G

Subjects: Ouabain*/Ouabain*/Ouabain*/pharmacology ; Polycystic Kidney, Autosomal Dominant*/Polycystic Kidney, Autosomal Dominant*/Polycystic Kidney, Autosomal Dominant*/pathology ; Polycystic Kidney, Autosomal Dominant*/Polycystic Kidney, Autosomal Dominant*/Polycystic Kidney, Autosomal Dominant*/metabolism

• Source: Experimental cell research [Exp Cell Res] 2025 Jan 01; Vol. 444 (1), pp. 114356. Date of Electronic Publication: 2024 Nov 23.Publisher: Academic Press Country of Publication: United States NLM ID: 0373226 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Ouabain, ATPase inhibitor, potentially enhances the effect of polyhexamethylene biguanide on Acanthamoeba castellanii.

• Authors : Shih KY; Department of Life Science, College of Life Sciences and Medicine, National Tsing Hua University, Hsinchu, Taiwan. Electronic address: .; Chang YT

Subjects: Biguanides*/Biguanides*/Biguanides*/pharmacology ; Acanthamoeba castellanii*/Acanthamoeba castellanii*/Acanthamoeba castellanii*/drug effects ; Ouabain*/Ouabain*/Ouabain*/pharmacology

• Source: International journal for parasitology. Drugs and drug resistance [Int J Parasitol Drugs Drug Resist] 2024 Aug; Vol. 25, pp. 100550. Date of Electronic Publication: 2024 May 22.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101576715 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Vascular smooth muscle BK channels limit ouabain-induced vasocontraction: Dual role of the Na/K-ATPase as a hub for Src-kinase and the Na/Ca-exchanger.

• Authors : Orth T; Research Division Cardiovascular Physiology, European Center of Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Pyanova A

Subjects: Ouabain*/Ouabain*/Ouabain*/pharmacology ; src-Family Kinases*/src-Family Kinases*/src-Family Kinases*/metabolism ; Sodium-Potassium-Exchanging ATPase*/Sodium-Potassium-Exchanging ATPase*/Sodium-Potassium-Exchanging ATPase*/metabolism

• Source: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2024 Sep; Vol. 38 (17), pp. e70046.Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print Cited

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Reports from Capital Medical University Highlight Recent Findings in Ouabain Therapy (Engineered Exosomes With Ouabain for H3k27m-mutated Dipg Therapy)

• Source: Obesity, Fitness & Wellness Week. November 9, 2024, p4274.

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Chronic Ouabain Targets Pore-Forming Claudin-2 and Ameliorates Radiation-Induced Damage to the Rat Intestinal Tissue Barrier.

• Authors : Markov AG; Department of General Physiology, St. Petersburg State University, 199034 St. Petersburg, Russia.; Livanova AA

Subjects: Claudin-2* ; Ouabain*/Ouabain*/Ouabain*/pharmacology; Male

• Source: International journal of molecular sciences [Int J Mol Sci] 2023 Dec 24; Vol. 25 (1). Date of Electronic Publication: 2023 Dec 24.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Development of Reproducible and Scalable Culture Conditions for In Vitro Maintenance of Pig Embryonic Stem Cells Using the Sandoz Inbred Swiss Mouse Thioguanine-Resistant Ouabain-Resistant Cell Line as a Feeder Layer.

• Authors : Ahn Y; Department of Agricultural Biotechnology, Animal Biotechnology Major, and Research Institute for Agriculture and Life Science; College of Veterinary Medicine

Subjects: Thioguanine*/Thioguanine*/Thioguanine*/metabolism ; Ouabain*/Ouabain*/Ouabain*/metabolism; Animals

• Source: Stem cells and development [Stem Cells Dev] 2023 Dec; Vol. 32 (23-24), pp. 747-757. Date of Electronic Publication: 2023 Oct 23.Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 101197107 Publication Model: Print-Electronic Cited Medium: Internet

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Folic acid does not have an anti-manic effect but protect the brain against oxidative stress in an animal model of mania induced by ouabain.

• Authors : Aguiar-Geraldo JM; Translational Psychiatry Laboratory, Graduate Program in Health Sciences, University of Southern Santa Catarina (UNESC), Criciúma, Brazil.; Possamai-Della T

Subjects: Antimanic Agents*/Antimanic Agents*/Antimanic Agents*/pharmacology ; Antimanic Agents*/Antimanic Agents*/Antimanic Agents*/therapeutic use ; Ouabain*/Ouabain*/Ouabain*/pharmacology

• Source: Journal of affective disorders [J Affect Disord] 2023 Aug 01; Vol. 334, pp. 307-316. Date of Electronic Publication: 2023 May 05.Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7906073 Publication Model: Print-Electronic Cited Medium:

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