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Academic Journal

QR-1011 restores defective ABCA4 splicing caused by multiple severe ABCA4 variants underlying Stargardt disease.

  • Authors : Kaltak M; R&D Department, ProQR Therapeutics, Zernikedreef 9, 2333 CK, Leiden, The Netherlands.; Department of Human Genetics, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525 GA, Nijmegen, The Netherlands.

Subjects: ATP-Binding Cassette Transporters*/ATP-Binding Cassette Transporters*/ATP-Binding Cassette Transporters*/genetics ; Stargardt Disease*/Stargardt Disease*/Stargardt Disease*/drug therapy ; Stargardt Disease*/Stargardt Disease*/Stargardt Disease*/genetics

  • Source: Scientific reports [Sci Rep] 2024 Jan 06; Vol. 14 (1), pp. 684. Date of Electronic Publication: 2024 Jan 06.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Targeting transforming growth factor-β2 by antisense oligodeoxynucleotide accelerates T cell-mediated tumor rejection in a humanized mouse model of triple-negative breast cancer.

  • Authors : Lee HK; Laboratory of Biochemistry and Immunology, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk, 28644, Republic of Korea.; Laboratory Animal Research Center, Chungbuk National University, Cheongju, Chungbuk, Republic of Korea.

Subjects: Oligodeoxyribonucleotides, Antisense*/Oligodeoxyribonucleotides, Antisense*/Oligodeoxyribonucleotides, Antisense*/pharmacology ; Transforming Growth Factor beta2*/Transforming Growth Factor beta2*/Transforming Growth Factor beta2*/antagonists & inhibitors ; Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/pathology

  • Source: Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2022 Sep; Vol. 71 (9), pp. 2213-2226. Date of Electronic Publication: 2022 Jan 31.Publisher: Springer Verlag Country of Publication: Germany NLM ID: 8605732 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The Role of Antisense Therapies Targeting Lipoprotein(a).

  • Authors : Plakogiannis R; Department of Pharmacy Practice, Arnold and Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, New York; and.

Subjects: Atherosclerosis/Atherosclerosis/Atherosclerosis/*drug therapy ; Dyslipidemias/Dyslipidemias/Dyslipidemias/*drug therapy ; Hypolipidemic Agents/Hypolipidemic Agents/Hypolipidemic Agents/*therapeutic use

  • Source: Journal of cardiovascular pharmacology [J Cardiovasc Pharmacol] 2021 Jul 01; Vol. 78 (1), pp. e5-e11.Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 7902492 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Phase Ib Clinical Trial of IGV-001 for Patients with Newly Diagnosed Glioblastoma.

  • Authors : Andrews DW; Department of Neurological Surgery, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania. .; Imvax, Inc., Philadelphia, Pennsylvania.

Subjects: Brain Neoplasms/Brain Neoplasms/Brain Neoplasms/*drug therapy ; Glioblastoma/Glioblastoma/Glioblastoma/*drug therapy ; Oligodeoxyribonucleotides, Antisense/Oligodeoxyribonucleotides, Antisense/Oligodeoxyribonucleotides, Antisense/*therapeutic use

  • Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2021 Apr 01; Vol. 27 (7), pp. 1912-1922. Date of Electronic Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

A Novel Peptide-Equipped Exosomes Platform for Delivery of Antisense Oligonucleotides.

  • Authors : Xu H; Lab of Biosystem and Microanalysis, State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, 200237, China.; Liao C

Subjects: Cell-Penetrating Peptides/Cell-Penetrating Peptides/Cell-Penetrating Peptides/*chemistry ; Drug Carriers/Drug Carriers/Drug Carriers/*chemistry ; Exosomes/Exosomes/Exosomes/*chemistry

  • Source: ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2021 Mar 10; Vol. 13 (9), pp. 10760-10767. Date of Electronic Publication: 2021 Feb 23.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101504991 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Optimized design of antisense oligomers for targeted rRNA depletion.

  • Authors : Phelps WA; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260, USA.; Carlson AE

Subjects: Computational Biology/Computational Biology/Computational Biology/*methods ; Oligodeoxyribonucleotides, Antisense/Oligodeoxyribonucleotides, Antisense/Oligodeoxyribonucleotides, Antisense/*genetics ; RNA/RNA/RNA/*genetics

  • Source: Nucleic acids research [Nucleic Acids Res] 2021 Jan 11; Vol. 49 (1), pp. e5.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Inotersen preserves or improves quality of life in hereditary transthyretin amyloidosis.

  • Authors : Coelho T; Hospital Santo António, Centro Hospitalar Universitário do Porto, Porto, Portugal.; Yarlas A

Subjects: Activities of Daily Living* ; Outcome Assessment, Health Care* ; Quality of Life* Amyloidosis, Hereditary, Transthyretin-Related

  • Source: Journal of neurology [J Neurol] 2020 Apr; Vol. 267 (4), pp. 1070-1079. Date of Electronic Publication: 2019 Dec 18.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0423161 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Evaluation of cell-penetrating peptide-peptide nucleic acid effect in the inhibition of cagA in Helicobacter pylori.

  • Authors : Javanmard Z; Microbial Biotechnology Research Center,Iran University of Medical Sciences, Tehran,Iran.; Department of Microbiology, School of Medicine,Iran University of Medical Sciences, Tehran,Iran.

Subjects: Antigens, Bacterial/Antigens, Bacterial/Antigens, Bacterial/*genetics ; Bacterial Proteins/Bacterial Proteins/Bacterial Proteins/*antagonists & inhibitors ; Bacterial Proteins/Bacterial Proteins/Bacterial Proteins/*genetics

  • Source: Acta microbiologica et immunologica Hungarica [Acta Microbiol Immunol Hung] 2020 Feb 11; Vol. 67 (1), pp. 66-72. Date of Electronic Publication: 2020 Feb 11.Publisher: Akademiai Kiado Country of Publication: Hungary NLM ID: 9434021 Publication Model: Electronic Cited Medium: Internet ISSN: 1588-2640

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Academic Journal

Peptide-conjugated oligonucleotides evoke long-lasting myotonic dystrophy correction in patient-derived cells and mice.

  • Authors : Klein AF; Sorbonne Université, Inserm, Association Institut de Myologie, Centre de Recherche en Myologie, Paris, France.; Varela MA

Subjects: Myotonic Dystrophy*/Myotonic Dystrophy*/Myotonic Dystrophy*/drug therapy ; Myotonic Dystrophy*/Myotonic Dystrophy*/Myotonic Dystrophy*/genetics ; Myotonic Dystrophy*/Myotonic Dystrophy*/Myotonic Dystrophy*/metabolism

  • Source: The Journal of clinical investigation [J Clin Invest] 2019 Nov 01; Vol. 129 (11), pp. 4739-4744.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print Cited Medium:

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Academic Journal

Targeting Listeria monocytogenes consensus sequence of internalin genes using an antisense molecule.

  • Authors : Kalani BS; Microbial Biotechnology Research Center, Iran University of Medical Sciences, Tehran, Iran; Department of Microbiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

Subjects: Anti-Bacterial Agents/Anti-Bacterial Agents/Anti-Bacterial Agents/*metabolism ; Bacterial Proteins/Bacterial Proteins/Bacterial Proteins/*antagonists & inhibitors ; Endocytosis/Endocytosis/Endocytosis/*drug effects

  • Source: Microbial pathogenesis [Microb Pathog] 2019 Nov; Vol. 136, pp. 103689. Date of Electronic Publication: 2019 Aug 21.Publisher: Academic Press Country of Publication: England NLM ID: 8606191 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  2,468 results for ""Oligodeoxyribonucleotides, Antisense""