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Academic Journal

Diagnostic Challenges due to a Germline Missense MSH2 Variant in a Patient With Immunotherapy-Responsive Locally Advanced Rectal Adenocarcinoma.

  • Authors : Evaristo G; Department of Pathology, The University of Chicago, Chicago, Illinois, USA.; Harmath C

Subjects: MutS Homolog 2 Protein*/MutS Homolog 2 Protein*/MutS Homolog 2 Protein*/genetics ; Adenocarcinoma*/Adenocarcinoma*/Adenocarcinoma*/genetics ; Adenocarcinoma*/Adenocarcinoma*/Adenocarcinoma*/therapy

  • Source: Cancer reports (Hoboken, N.J.) [Cancer Rep (Hoboken)] 2024 Dec; Vol. 7 (12), pp. e70037.Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101747728 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

The genetic landscape of Lynch syndrome in the Israeli population.

  • Authors : Shtaya AA; Recanati Genetics Institute, Faculty of Medicine, Rabin Medical Center - Beilinson Hospital, Tel Aviv University, Petach Tikva, Tel Aviv, Israel.; Unit of Gastroenterology, Lady Davis Carmel Medical Center, Haifa, Israel.

Subjects: Colorectal Neoplasms, Hereditary Nonpolyposis*/Colorectal Neoplasms, Hereditary Nonpolyposis*/Colorectal Neoplasms, Hereditary Nonpolyposis*/genetics ; MutS Homolog 2 Protein*/MutS Homolog 2 Protein*/MutS Homolog 2 Protein*/genetics; Humans

  • Source: Familial cancer [Fam Cancer] 2024 Nov 15; Vol. 24 (1), pp. 6. Date of Electronic Publication: 2024 Nov 15.Publisher: Springer Country of Publication: Netherlands NLM ID: 100898211 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-7292

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Academic Journal

A novel mouse model recapitulating the MMR-defective SCLC subtype uncovers an actionable sensitivity to immune checkpoint blockade.

  • Authors : Ibruli O; Department of Translational Genomics, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.; Department I of Internal Medicine, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.

Subjects: Immune Checkpoint Inhibitors*/Immune Checkpoint Inhibitors*/Immune Checkpoint Inhibitors*/pharmacology ; Immune Checkpoint Inhibitors*/Immune Checkpoint Inhibitors*/Immune Checkpoint Inhibitors*/therapeutic use ; Small Cell Lung Carcinoma*/Small Cell Lung Carcinoma*/Small Cell Lung Carcinoma*/genetics

  • Source: Journal of cancer research and clinical oncology [J Cancer Res Clin Oncol] 2024 Nov 14; Vol. 150 (11), pp. 496. Date of Electronic Publication: 2024 Nov 14.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 7902060 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1335

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Academic Journal

Association of multilocus sequence typing, MSH2 gene mutations, and antifungal resistance in Candida glabrata: implications for clinical outcomes in Chinese hospitals.

  • Authors : Zhang G; Department of Laboratory Medicine, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200030, China.; Chen Y

Subjects: Candida glabrata*/Candida glabrata*/Candida glabrata*/drug effects ; Candida glabrata*/Candida glabrata*/Candida glabrata*/genetics ; Antifungal Agents*/Antifungal Agents*/Antifungal Agents*/pharmacology

  • Source: Annals of clinical microbiology and antimicrobials [Ann Clin Microbiol Antimicrob] 2024 Nov 08; Vol. 23 (1), pp. 100. Date of Electronic Publication: 2024 Nov 08.Publisher: BioMed Central Country of Publication: England NLM ID: 101152152 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-0711

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Academic Journal

Immunostaining for Mismatch Repair Complex Proteins Impacts on Clinical-Pathological Characteristics and Prognosis of Adenoid Cystic Carcinoma of Salivary Glands.

Subjects: Carcinoma, Adenoid Cystic*/Carcinoma, Adenoid Cystic*/Carcinoma, Adenoid Cystic*/pathology ; Carcinoma, Adenoid Cystic*/Carcinoma, Adenoid Cystic*/Carcinoma, Adenoid Cystic*/metabolism ; Salivary Gland Neoplasms*/Salivary Gland Neoplasms*/Salivary Gland Neoplasms*/pathology

  • Source: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology [J Oral Pathol Med] 2024 Nov; Publisher: Wiley-Blackwell Country of Publication: Denmark NLM ID: 8911934 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Intronic Variants in the MSH2 (rs2303426 and rs10179950) and PMS2 (rs2286681 and rs62456178) Genes Are Not Associated with Colorectal Cancer in Mexican Patients.

  • Authors : Rico-Méndez MA; Doctorado en Genética Humana e Instituto de Genética Humana 'Dr. Enrique Corona Rivera', Departamento de Biología Molecular y Genómica, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Mexico.; López-Ceballos AG

Subjects: Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/genetics ; MutS Homolog 2 Protein*/MutS Homolog 2 Protein*/MutS Homolog 2 Protein*/genetics ; Mismatch Repair Endonuclease PMS2*/Mismatch Repair Endonuclease PMS2*/Mismatch Repair Endonuclease PMS2*/genetics

  • Source: Genes [Genes (Basel)] 2024 Oct 26; Vol. 15 (11). Date of Electronic Publication: 2024 Oct 26.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101551097 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4425

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Academic Journal

Circ_0025373 inhibits carbon black nanoparticles-induced malignant transformation of human bronchial epithelial cells by affecting DNA damage through binding to MSH2.

  • Authors : Zhang H; The Key Laboratory of Advanced Interdisciplinary Studies, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 511436, China; Institute for Chemical Carcinogenesis, Guangzhou Medical University, Guangzhou 511436, China.

Subjects: MutS Homolog 2 Protein*/MutS Homolog 2 Protein*/MutS Homolog 2 Protein*/metabolism ; MutS Homolog 2 Protein*/MutS Homolog 2 Protein*/MutS Homolog 2 Protein*/genetics ; Epithelial Cells*/Epithelial Cells*/Epithelial Cells*/drug effects

  • Source: Environment international [Environ Int] 2024 Sep; Vol. 191, pp. 109001. Date of Electronic Publication: 2024 Sep 07.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 7807270 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

HLTF resolves G4s and promotes G4-induced replication fork slowing to maintain genome stability.

  • Authors : Bai G; Department of Chemical & Systems Biology, Stanford University, Stanford, CA 94305, USA.; Endres T

Subjects: Genomic Instability* ; DNA Replication* ; G-Quadruplexes*

  • Source: Molecular cell [Mol Cell] 2024 Aug 22; Vol. 84 (16), pp. 3044-3060.e11. Date of Electronic Publication: 2024 Aug 13.Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

LINC01232 targeting miR-1250-3p/MSH2 axis attenuates mesangial cell proliferation and fibrosis in diabetic nephropathy.

  • Authors : Tu X; Nephrology Department, Wuhan Asia General Hospital, Wuhan, 430050, Hubei, China.; Zhang H

Subjects: Cell Proliferation* ; Diabetic Nephropathies*/Diabetic Nephropathies*/Diabetic Nephropathies*/metabolism ; Diabetic Nephropathies*/Diabetic Nephropathies*/Diabetic Nephropathies*/pathology

  • Source: Molecular and cellular biochemistry [Mol Cell Biochem] 2024 Aug; Vol. 479 (8), pp. 2093-2103. Date of Electronic Publication: 2023 Aug 29.Publisher: Springer Country of Publication: Netherlands NLM ID: 0364456 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Nfe2l2/NRF2 Deletion Attenuates Tumorigenesis and Increases Bacterial Diversity in a Mouse Model of Lynch Syndrome.

  • Authors : Haller F; Division of Gastroenterology and Hepatology, Department of Internal Medicine 3, Medical University of Vienna, Vienna, Austria.; Jimenez K

Subjects: NF-E2-Related Factor 2*/NF-E2-Related Factor 2*/NF-E2-Related Factor 2*/metabolism ; NF-E2-Related Factor 2*/NF-E2-Related Factor 2*/NF-E2-Related Factor 2*/genetics ; Colorectal Neoplasms, Hereditary Nonpolyposis*/Colorectal Neoplasms, Hereditary Nonpolyposis*/Colorectal Neoplasms, Hereditary Nonpolyposis*/genetics

  • Source: Cancer prevention research (Philadelphia, Pa.) [Cancer Prev Res (Phila)] 2024 Jul 02; Vol. 17 (7), pp. 311-324.Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101479409 Publication Model: Print Cited Medium:

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  • 1-10 of  3,252 results for ""MutS Homolog 2 Protein""