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Recent Studies from Washington State University Add New Data to Antiinfectives (Age-dependent Abundance of Cyp450 Enzymes Involved In Metronidazole Metabolism: Application To Pediatric Pbpk Modeling)

• Source: Obesity, Fitness & Wellness Week. August 3, 2024, 352

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Age-Dependent Abundance of CYP450 Enzymes Involved in Metronidazole Metabolism: Application to Pediatric PBPK Modeling.

• Authors : Parvez MM; Department of Pharmaceutical Sciences, Washington State University, Spokane, Washington, USA.; Thakur A

Subjects: Metronidazole*/Metronidazole*/Metronidazole*/pharmacokinetics ; Metronidazole*/Metronidazole*/Metronidazole*/metabolism ; Microsomes, Liver*/Microsomes, Liver*/Microsomes, Liver*/metabolism

• Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2024 Oct; Vol. 116 (4), pp. 1090-1099. Date of Electronic Publication: 2024 Jul 02.Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535

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Development of New PCR Protocols to Detect Genetic Diversity in the Metronidazole Metabolism Genes in Susceptible and Refractory Clinical Samples of Giardia duodenalis.

• Authors : Asghari A; Department of Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.; Mahdavi F

Subjects: Metronidazole*/Metronidazole*/Metronidazole*/pharmacology ; Giardia lamblia*/Giardia lamblia*/Giardia lamblia*/genetics ; Giardia lamblia*/Giardia lamblia*/Giardia lamblia*/drug effects

• Source: Acta parasitologica [Acta Parasitol] 2024 Mar; Vol. 69 (1), pp. 1073-1077. Date of Electronic Publication: 2024 Mar 18.Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 9301947 Publication Model: Print-Electronic Cited Medium:

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Genetic diversity in the metronidazole metabolism genes nitroreductases and pyruvate ferredoxin oxidoreductases in susceptible and refractory clinical samples of Giardia lamblia.

• Authors : Saghaug, Christina S.; Gamlem, Astrid L.; Hauge, Kirsti B.

• Source: International Journal for Parasitology: Drugs & Drug Resistance; Apr2023, Vol. 21, p51-60, 10p

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Genetic variation in metronidazole metabolism and oxidative stress pathways in clinical Giardia lamblia assemblage A and B isolates

• Authors : Saghaug, Christina S.; Klotz, Christian; Kallio, Juha P.

• Source: Infection and Drug Resistance. May, 2019, p1221, 15 p.

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Erratum: Genetic Variation in Metronidazole Metabolism and Oxidative Stress Pathways in Clinical Giardia lamblia Assemblage A and B Isolates [Corrigendum].

• Source: Infection and drug resistance [Infect Drug Resist] 2021 Sep 14; Vol. 14, pp. 3727-3728. Date of Electronic Publication: 2021 Sep 14 (Print Publication: 2021).Publisher: Dove Medical Press Country of Publication: New Zealand NLM ID: 101550216 Publication Model: eCollection Cited Medium: Print ISSN:

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Agricola

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Metronidazole Metabolism in Neonates and the Interplay Between Ontogeny and Genetic Variation.

• Authors : Wang LA; Gonzalez D ...

Subjects: Genetic Variation*; Anti-Infective Agents/Anti-Infective Agents/Anti-Infective Agents/*metabolism ; Anti-Infective Agents/Anti-Infective Agents/Anti-Infective Agents/*pharmacokinetics

• Source: Journal of clinical pharmacology [J Clin Pharmacol] 2017 Feb; Vol. 57 (2), pp. 230-234. Date of Electronic Publication: 2016 Aug 23.Publisher: Wiley Country of Publication: England NLM ID: 0366372 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4604

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Faulty metronidazole metabolism signals liver dysfunction despite HCV clearance.

• Source: World Disease Weekly. 2005, pages. 1177

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Faulty metronidazole metabolism signals liver dysfunction despite HCV clearance.

• Source: Health & Medicine Week. 2005, pages. 1181

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