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Reports Outline Acute Lymphoblastic Leukemia Findings from Institute of Hematology and Blood Diseases Hospital (Correlation Between Methylation Level of Slc19a1 Promoter Region and Methotrexate Metabolism In Adult Acute Lymphoblastic Leukemia)

• Source: Obesity, Fitness & Wellness Week. May 6, 2023, 2368

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Correlation between methylation level of the SLC19A1 promoter region and methotrexate metabolism in adult acute lymphoblastic leukemia.

• Authors : Huang X; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, 300020, China.; Hao Q

Subjects: Methotrexate*/Methotrexate*/Methotrexate*/adverse effects ; Precursor Cell Lymphoblastic Leukemia-Lymphoma*/Precursor Cell Lymphoblastic Leukemia-Lymphoma*/Precursor Cell Lymphoblastic Leukemia-Lymphoma*/drug therapy ; Precursor Cell Lymphoblastic Leukemia-Lymphoma*/Precursor Cell Lymphoblastic Leukemia-Lymphoma*/Precursor Cell Lymphoblastic Leukemia-Lymphoma*/genetics

• Source: Pharmacogenomics [Pharmacogenomics] 2023 Apr; Vol. 24 (5), pp. 261-268. Date of Electronic Publication: 2023 Mar 31.Publisher: Future Medicine Ltd Country of Publication: England NLM ID: 100897350 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Correlation between Methylation Level of the SLC19A1Promoter Region and Methotrexate Metabolism in Adult Acute Lymphoblastic Leukemia

• Authors : Huang, Xianqi; Hao, Qishan; Fang, Qiuyun

• Source: Pharmacogenomics; April 2023, Vol. 24 Issue: 5 p261-268, 8p

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Reports from Ulster University Describe Recent Advances in Rheumatoid Arthritis (Clinical and Laboratory Associations with Methotrexate Metabolism Gene Polymorphisms in Rheumatoid Arthritis)

• Source: Obesity, Fitness & Wellness Week. October 17, 2020, 4723

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Researchers from St. Jude Children's Research Hospital Report Recent Findings in Leukemia (Effects of germline variants in DHFR and FPGS on methotrexate metabolism and relapse of leukemia)

• Source: Obesity, Fitness & Wellness Week. May 30, 2020, 5545

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Clinical and Laboratory Associations with Methotrexate Metabolism Gene Polymorphisms in Rheumatoid Arthritis.

• Authors : D'Cruz LG; Northern Ireland Centre for Stratified Medicine (NICSM), Biomedical Sciences Research Institute, Ulster University, C-TRIC Building, Londonderry BT47 6SB, UK.; Respiratory Medicine Department and Clinical Trials Unit, Queen Alexandra Hospital, Portsmouth PO6 3LY, UK.

• Source: Journal of personalized medicine [J Pers Med] 2020 Sep 26; Vol. 10 (4). Date of Electronic Publication: 2020 Sep 26.Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101602269 Publication Model: Electronic Cited Medium: Print ISSN: 2075-4426

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Effects of germline DHFR and FPGS variants on methotrexate metabolism and relapse of leukemia.

• Authors : Tulstrup M; Department of Pediatrics and Adolescent Medicine and.; Department of Hematology, University Hospital Rigshospitalet, Copenhagen, Denmark.

Subjects: Polymorphism, Single Nucleotide*; Methotrexate/Methotrexate/Methotrexate/*analogs & derivatives ; Neoplasm Recurrence, Local/Neoplasm Recurrence, Local/Neoplasm Recurrence, Local/*pathology

• Source: Blood [Blood] 2020 Sep 03; Vol. 136 (10), pp. 1161-1168.Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020

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Effects of germline DHFRand FPGSvariants on methotrexate metabolism and relapse of leukemia

• Authors : Tulstrup, Morten; Moriyama, Takaya; Jiang, Chuang

• Source: Blood; September 2020, Vol. 136 Issue: 10 p1161-1168, 8p

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The importance of inhibition of a catabolic pathway of methotrexate metabolism in its efficacy for rheumatoid arthritis.

• Authors : Morgan SL; Division of Clinical Immunology and Rheumatology, Department of Medicine, School of Medicine, The University of Alabama at Birmingham, Birmingham, AL, United States. Electronic address: .; Baggott JE

Subjects: Arthritis, Rheumatoid/Arthritis, Rheumatoid/Arthritis, Rheumatoid/*drug therapy ; Methotrexate/Methotrexate/Methotrexate/*pharmacology; Animals

• Source: Medical hypotheses [Med Hypotheses] 2019 Jan; Vol. 122, pp. 10-15. Date of Electronic Publication: 2018 Oct 11.Publisher: Eden Press Country of Publication: United States NLM ID: 7505668 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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New Rheumatoid Arthritis Study Findings Recently Were Reported by Researchers at University of Alabama (The Importance of Inhibition of a Catabolic Pathway of Methotrexate Metabolism In Its Efficacy for Rheumatoid Arthritis)

• Source: Health & Medicine Week. March 15, 2019, 2925

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