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Academic Journal

Janus kinase 1 inhibitor abrocitinib for isolated nail lichen planus: a case report and literature review.

  • Authors : He J; School of Medicine, Nankai university, Tianjin, China.; Department of Dermatology, First Medical Center of Chinese PLA General Hospital, Beijing, China.

Subjects: Lichen Planus*/Lichen Planus*/Lichen Planus*/drug therapy ; Lichen Planus*/Lichen Planus*/Lichen Planus*/pathology ; Nail Diseases*/Nail Diseases*/Nail Diseases*/drug therapy

  • Source: The Journal of dermatological treatment [J Dermatolog Treat] 2024 Dec; Vol. 35 (1), pp. 2434094. Date of Electronic Publication: 2024 Nov 27.Publisher: Informa Healthcare Country of Publication: England NLM ID: 8918133 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Revisiting Structure-activity Relationships: Unleashing the potential of selective Janus kinase 1 inhibitors.

  • Authors : Shan M; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, People's Republic of China.; Zhao X

Subjects: Janus Kinase 1*/Janus Kinase 1*/Janus Kinase 1*/antagonists & inhibitors ; Janus Kinase 1*/Janus Kinase 1*/Janus Kinase 1*/metabolism ; Protein Kinase Inhibitors*/Protein Kinase Inhibitors*/Protein Kinase Inhibitors*/pharmacology

  • Source: Bioorganic chemistry [Bioorg Chem] 2024 Aug; Vol. 149, pp. 107506. Date of Electronic Publication: 2024 May 29.Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The Janus kinase 1 is critical for pancreatic cancer initiation and progression.

  • Authors : Shrestha H; Department of Oncology, Wayne State University School of Medicine and Tumor Biology Program, Barbara Ann Karmanos Cancer Institute, Detroit, MI 48201, USA.; Rädler PD

Subjects: Carcinoma, Pancreatic Ductal*/Carcinoma, Pancreatic Ductal*/Carcinoma, Pancreatic Ductal*/pathology ; Carcinoma, Pancreatic Ductal*/Carcinoma, Pancreatic Ductal*/Carcinoma, Pancreatic Ductal*/genetics ; Carcinoma, Pancreatic Ductal*/Carcinoma, Pancreatic Ductal*/Carcinoma, Pancreatic Ductal*/metabolism

  • Source: Cell reports [Cell Rep] 2024 May 28; Vol. 43 (5), pp. 114202. Date of Electronic Publication: 2024 May 10.Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Reversible effects on female rat fertility with abrocitinib, a Janus kinase 1 inhibitor.

Subjects: Fertility*/Fertility*/Fertility*/drug effects ; Janus Kinase 1*/Janus Kinase 1*/Janus Kinase 1*/antagonists & inhibitors ; Janus Kinase 1*/Janus Kinase 1*/Janus Kinase 1*/metabolism

  • Source: Birth defects research [Birth Defects Res] 2024 May; Vol. 116 (5), pp. e2345.Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101701004 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Myelin oligodendrocyte glycoprotein reactive Th17 cells drive Janus Kinase 1 dependent transcriptional reprogramming in astrocytes and alter cell surface cytokine receptor profiles during experimental autoimmune encephalomyelitis.

  • Authors : Milne SM; Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV, 26506, USA.; Lahiri A

Subjects: Encephalomyelitis, Autoimmune, Experimental*/Encephalomyelitis, Autoimmune, Experimental*/Encephalomyelitis, Autoimmune, Experimental*/metabolism ; Encephalomyelitis, Autoimmune, Experimental*/Encephalomyelitis, Autoimmune, Experimental*/Encephalomyelitis, Autoimmune, Experimental*/immunology ; Encephalomyelitis, Autoimmune, Experimental*/Encephalomyelitis, Autoimmune, Experimental*/Encephalomyelitis, Autoimmune, Experimental*/pathology

  • Source: Scientific reports [Sci Rep] 2024 Jun 07; Vol. 14 (1), pp. 13146. Date of Electronic Publication: 2024 Jun 07.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

[Electroacupuncture improves pulmonary function by reducing inflammatory reaction via inhibiting miR-19b-3p to regulate SOCS3/JAK1/STAT3 signaling pathway in mice with chronic obstructive pulmonary disease].

  • Authors : Wu HH; College of Acupuncture-moxibustion and Tuina, Anhui University of Chinese Medicine, Hefei 230038, China.; Pan Z

Subjects: MicroRNAs*/MicroRNAs*/MicroRNAs*/genetics ; MicroRNAs*/MicroRNAs*/MicroRNAs*/metabolism ; Suppressor of Cytokine Signaling 3 Protein*/Suppressor of Cytokine Signaling 3 Protein*/Suppressor of Cytokine Signaling 3 Protein*/genetics

  • Source: Zhen ci yan jiu = Acupuncture research [Zhen Ci Yan Jiu] 2024 Dec 25; Vol. 49 (12), pp. 1248-1256.Publisher: Institute Of Acupuncture And Moxibustion Country of Publication: China NLM ID: 8507710 Publication Model: Print Cited Medium: Print ISSN:

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Academic Journal

FGFR3 Upregulates Interferon-Stimulated Genes Via the JAK1-STAT1 Signaling Pathway in HPV2 E2 Stable Expressing Keratinocytes.

  • Authors : Guo Q; Department of Dermatology, First Medical Center of Chinese People's Liberation Army General Hospital, Beijing, China.; Hospital for Skin Diseases, Shandong First Medical University, Jinan, China.

Subjects: Keratinocytes*/Keratinocytes*/Keratinocytes*/virology ; Keratinocytes*/Keratinocytes*/Keratinocytes*/metabolism ; Keratinocytes*/Keratinocytes*/Keratinocytes*/immunology

  • Source: Journal of medical virology [J Med Virol] 2025 Jan; Vol. 97 (1), pp. e70147.Publisher: Wiley-Liss Country of Publication: United States NLM ID: 7705876 Publication Model: Print Cited Medium: Internet ISSN: 1096-9071

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Academic Journal

Identification of RdRp-NiRAN/JAK1 Dual-Target Drugs for COVID-19 Treatment.

  • Authors : Zhao H; Institute of Frontier Chemistry, School of Chemistry and Chemical Engineering, Shandong University, Qingdao 266237, China.; Chang X

Subjects: Janus Kinase 1*/Janus Kinase 1*/Janus Kinase 1*/metabolism ; Janus Kinase 1*/Janus Kinase 1*/Janus Kinase 1*/antagonists & inhibitors ; Janus Kinase 1*/Janus Kinase 1*/Janus Kinase 1*/chemistry

  • Source: The journal of physical chemistry. B [J Phys Chem B] 2024 Dec 12; Vol. 128 (49), pp. 12066-12077. Date of Electronic Publication: 2024 Dec 03.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101157530 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Muti-target rationale design of novel substituted N-phenyl-2-((6-phenylpyridazin-3-yl)thio)acetamide candidates as telomerase/JAK1/STAT3/TLR4 inhibitors: In vitro and in vivo investigations.

  • Authors : Shaldam MA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh 33516, Egypt. Electronic address: .; Mousa MHA

Subjects: Janus Kinase 1*/Janus Kinase 1*/Janus Kinase 1*/antagonists & inhibitors ; Janus Kinase 1*/Janus Kinase 1*/Janus Kinase 1*/metabolism ; Telomerase*/Telomerase*/Telomerase*/antagonists & inhibitors

  • Source: Bioorganic chemistry [Bioorg Chem] 2024 Dec; Vol. 153, pp. 107843. Date of Electronic Publication: 2024 Sep 24.Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Promiscuous Janus kinase binding to cytokine receptors modulates signaling efficiencies and contributes to cytokine pleiotropy.

  • Authors : Zoler E; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.; Meyer T

Subjects: Receptor, Interferon alpha-beta*/Receptor, Interferon alpha-beta*/Receptor, Interferon alpha-beta*/metabolism ; Receptor, Interferon alpha-beta*/Receptor, Interferon alpha-beta*/Receptor, Interferon alpha-beta*/genetics ; Signal Transduction*

  • Source: Science signaling [Sci Signal] 2024 Nov 19; Vol. 17 (863), pp. eadl1892. Date of Electronic Publication: 2024 Nov 19.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Print-Electronic

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  • 1-10 of  22,557 results for ""Janus Kinase 1""