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Academic Journal

JAG1 mediates apoptosis in herpes simplex keratitis by suppressing autophagy via ROS/JAG1/NOTCH1/pULK1 signaling pathway.

  • Authors : Chang J; School of Medicine, Southeast University, Nanjing, 210009, Jiangsu, China.; Department of Ophthalmology, Jinling Hospital, Nanjing, 210002, Jiangsu, China.

Subjects: Receptor, Notch1*/Receptor, Notch1*/Receptor, Notch1*/metabolism ; Receptor, Notch1*/Receptor, Notch1*/Receptor, Notch1*/genetics ; Jagged-1 Protein*/Jagged-1 Protein*/Jagged-1 Protein*/metabolism

  • Source: Cell biology and toxicology [Cell Biol Toxicol] 2024 Dec 20; Vol. 41 (1), pp. 1. Date of Electronic Publication: 2024 Dec 20.Publisher: Springer Country of Publication: Switzerland NLM ID: 8506639 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-6822

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Academic Journal

Jag1 represses Notch activation in lateral supporting cells and inhibits an outer hair cell fate in the medial cochlea.

  • Authors : de Haan S; Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm 17177, Sweden.; Laboratory of Cochlear Development, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD 20892, USA.

Subjects: Jagged-1 Protein*/Jagged-1 Protein*/Jagged-1 Protein*/metabolism ; Jagged-1 Protein*/Jagged-1 Protein*/Jagged-1 Protein*/genetics ; Hair Cells, Auditory, Outer*/Hair Cells, Auditory, Outer*/Hair Cells, Auditory, Outer*/metabolism

  • Source: Development (Cambridge, England) [Development] 2024 Nov 01; Vol. 151 (21). Date of Electronic Publication: 2024 Nov 05.Publisher: Company Of Biologists Limited Country of Publication: England NLM ID: 8701744 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Jag1 insufficiency alters liver fibrosis via T cell and hepatocyte differentiation defects.

  • Authors : Mašek J; Department of Cell and Molecular Biology, Karolinska Institute, SE-171 77 Solna, Stockholm, Sweden. .; Department of Cell Biology, Faculty of Science, Charles University, Viničná 7, 128 00, Prague 2, Czech Republic. .

Subjects: Jagged-1 Protein*/Jagged-1 Protein*/Jagged-1 Protein*/metabolism ; Jagged-1 Protein*/Jagged-1 Protein*/Jagged-1 Protein*/genetics ; Liver Cirrhosis*/Liver Cirrhosis*/Liver Cirrhosis*/pathology

  • Source: EMBO molecular medicine [EMBO Mol Med] 2024 Nov; Vol. 16 (11), pp. 2946-2975. Date of Electronic Publication: 2024 Oct 02.Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Differential Effects of Four Canonical Notch-Activating Ligands on c-Kit+ Cardiac Progenitor Cells.

  • Authors : Robeson M; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA.; Goudy SL

Subjects: Jagged-1 Protein*/Jagged-1 Protein*/Jagged-1 Protein*/metabolism ; Jagged-1 Protein*/Jagged-1 Protein*/Jagged-1 Protein*/genetics ; Receptors, Notch*/Receptors, Notch*/Receptors, Notch*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Oct 17; Vol. 25 (20). Date of Electronic Publication: 2024 Oct 17.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Delivery of a Jagged1-PEG-MAL hydrogel with pediatric human bone cells regenerates critically sized craniofacial bone defects.

  • Authors : Kamalakar A; Department of Pediatric Otolaryngology, Emory University, Atlanta, United States.; Tobin B

Subjects: Jagged-1 Protein*/Jagged-1 Protein*/Jagged-1 Protein*/metabolism ; Jagged-1 Protein*/Jagged-1 Protein*/Jagged-1 Protein*/genetics ; Bone Regeneration*

  • Source: ELife [Elife] 2024 Oct 14; Vol. 13. Date of Electronic Publication: 2024 Oct 14.Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet

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Academic Journal

The N-acetylglucosaminyltransferase Radical fringe contributes to defects in JAG1-dependent turnover and signaling of NOTCH3 CADASIL mutants.

  • Authors : Suzuki S; Department of Biochemistry, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Chiba, Japan.; Mashiko T

Subjects: Receptor, Notch3*/Receptor, Notch3*/Receptor, Notch3*/metabolism ; Receptor, Notch3*/Receptor, Notch3*/Receptor, Notch3*/genetics ; Jagged-1 Protein*/Jagged-1 Protein*/Jagged-1 Protein*/metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2024 Oct; Vol. 300 (10), pp. 107787. Date of Electronic Publication: 2024 Sep 19.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Dysbiosis-activated IL-17-producing T cells promote skin immunopathological progression in mice deficient of the Notch ligand Jag1 in keratinocytes.

  • Authors : Song EH; The Molecular, Cellular, and Integrative Biosciences (MCIBS) Graduate Program, The Pennsylvania State University, PA, USA; Department of Microbiology, Immunology and Molecular Genetics, University of Texas Health Science Center San Antonio, TX, USA.

Subjects: Jagged-1 Protein*/Jagged-1 Protein*/Jagged-1 Protein*/metabolism ; Jagged-1 Protein*/Jagged-1 Protein*/Jagged-1 Protein*/genetics ; Jagged-1 Protein*/Jagged-1 Protein*/Jagged-1 Protein*/immunology

  • Source: Journal of dermatological science [J Dermatol Sci] 2024 Oct; Vol. 116 (1), pp. 14-23. Date of Electronic Publication: 2024 Sep 06.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9011485 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Notch signaling regulates mineralization via microRNA modulation in dental pulp stem cells.

  • Authors : Kulthanaamondhita P; Center of Excellence for Dental Stem Cell Biology and Department of Anatomy, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand.; Kornsuthisopon C

Subjects: Dental Pulp*/Dental Pulp*/Dental Pulp*/cytology ; Dental Pulp*/Dental Pulp*/Dental Pulp*/metabolism ; MicroRNAs*/MicroRNAs*/MicroRNAs*/genetics

  • Source: Oral diseases [Oral Dis] 2024 Oct; Vol. 30 (7), pp. 4547-4557. Date of Electronic Publication: 2024 Jan 19.Publisher: Munksgaard Country of Publication: Denmark NLM ID: 9508565 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1601-0825

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Academic Journal

Jagged1-Notch1 Signaling Pathway Induces M1 Microglia to Disrupt the Barrier Function of Retinal Microvascular Endothelial Cells.

  • Authors : Wu X; School of Medicine, South China University of Technology, Guangzhou, China.; Guangdong Eye Institute, Department of Ophthalmology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.

Subjects: Microglia*/Microglia*/Microglia*/metabolism ; Jagged-1 Protein*/Jagged-1 Protein*/Jagged-1 Protein*/metabolism ; Jagged-1 Protein*/Jagged-1 Protein*/Jagged-1 Protein*/genetics

  • Source: Current eye research [Curr Eye Res] 2024 Oct; Vol. 49 (10), pp. 1098-1106. Date of Electronic Publication: 2024 May 23.Publisher: Informa Healthcare Country of Publication: England NLM ID: 8104312 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Investigation of cryptic JAG1 splice variants as a cause of Alagille syndrome and performance evaluation of splice predictor tools.

  • Authors : Keefer-Jacques E; Division of Genomic Diagnostics, Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.; Valente N

Subjects: Alagille Syndrome*/Alagille Syndrome*/Alagille Syndrome*/genetics ; Alagille Syndrome*/Alagille Syndrome*/Alagille Syndrome*/diagnosis ; Jagged-1 Protein*/Jagged-1 Protein*/Jagged-1 Protein*/genetics

  • Source: HGG advances [HGG Adv] 2024 Oct 10; Vol. 5 (4), pp. 100351. Date of Electronic Publication: 2024 Sep 06.Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101772885 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  1,727 results for ""Jagged-1 Protein""