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Academic Journal

Interleukin-5 as a pleiotropic cytokine orchestrating airway type 2 inflammation: Effects on and beyond eosinophils.

  • Authors : Buchheit KM; Division of Allergy and Clinical Immunology, AERD Center, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Shaw D

Subjects: Interleukin-5*/Interleukin-5*/Interleukin-5*/metabolism ; Eosinophils*/Eosinophils*/Eosinophils*/immunology ; Eosinophils*/Eosinophils*/Eosinophils*/metabolism

  • Source: Allergy [Allergy] 2024 Oct; Vol. 79 (10), pp. 2662-2679.Publisher: Wiley-Blackwell Country of Publication: Denmark NLM ID: 7804028 Publication Model: Print Cited Medium: Internet ISSN: 1398-9995

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Academic Journal

Group 2 innate lymphoid cells are a non-redundant source of interleukin-5 required for development and function of murine B1 cells.

  • Authors : Troch KF; Charité - Universitätsmedizin Berlin, Corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Microbiology, Infectious Diseases and Immunology, Hindenburgdamm 30, Berlin, Germany.; Jakob MO

Subjects: Immunity, Innate* ; Interleukin-5*/Interleukin-5*/Interleukin-5*/metabolism ; Interleukin-5*/Interleukin-5*/Interleukin-5*/immunology

  • Source: Nature communications [Nat Commun] 2024 Dec 04; Vol. 15 (1), pp. 10566. Date of Electronic Publication: 2024 Dec 04.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Interleukin-5 alleviates cardiac remodelling via the STAT3 pathway in angiotensin II-infused mice.

  • Authors : Shen C; Department of Cardiovascular Medicine, The First Affiliated Hospital of Ningbo University, Ningbo, China.; Wu N

Subjects: Angiotensin II*/Angiotensin II*/Angiotensin II*/pharmacology ; STAT3 Transcription Factor*/STAT3 Transcription Factor*/STAT3 Transcription Factor*/metabolism ; STAT3 Transcription Factor*/STAT3 Transcription Factor*/STAT3 Transcription Factor*/genetics

  • Source: Journal of cellular and molecular medicine [J Cell Mol Med] 2024 Jul; Vol. 28 (13), pp. e18493.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101083777 Publication Model: Print Cited Medium: Internet ISSN: 1582-4934

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Academic Journal

Single-cell proteomics and transcriptomics capture eosinophil development and identify the role of IL-5 in their lineage transit amplification.

  • Authors : Jorssen J; Laboratory of Cellular and Molecular Immunology, GIGA Institute, Faculty of Veterinary Medicine, University of Liege, B34 Avenue de l'Hopital 1, 4000 Liege, Belgium.; Van Hulst G

Subjects: Eosinophils*/Eosinophils*/Eosinophils*/immunology ; Eosinophils*/Eosinophils*/Eosinophils*/metabolism ; Interleukin-5*/Interleukin-5*/Interleukin-5*/metabolism

  • Source: Immunity [Immunity] 2024 Jul 09; Vol. 57 (7), pp. 1549-1566.e8. Date of Electronic Publication: 2024 May 21.Publisher: Cell Press Country of Publication: United States NLM ID: 9432918 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

3-carene supresses inflammatory cytokine interleukin-4, interleukin-5 and interleukin-13 in a murine model of asthma.

  • Authors : Kim K; College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of Korea.; Kim Y

Subjects: Asthma*/Asthma*/Asthma*/drug therapy ; Asthma*/Asthma*/Asthma*/pathology ; Interleukin-13*/Interleukin-13*/Interleukin-13*/metabolism

  • Source: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society [J Physiol Pharmacol] 2024 Apr; Vol. 75 (2), pp. 195-203. Date of Electronic Publisher: Polish Physiological Society Country of Publication: Poland NLM ID: 9114501 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Anti-IL-5 and anti-IL-5R biologics for severe asthma. Are there any differences in their effects?

Subjects: Asthma*/Asthma*/Asthma*/drug therapy ; Asthma*/Asthma*/Asthma*/physiopathology ; Interleukin-5*/Interleukin-5*/Interleukin-5*/antagonists & inhibitors

  • Source: The Journal of asthma : official journal of the Association for the Care of Asthma [J Asthma] 2024 Aug; Vol. 61 (8), pp. 857-866. Date of Electronic Publication: 2024 Feb 09.Publisher: Informa Healthcare Country of Publication: England NLM ID: 8106454 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Asthma loss of control after switch from anti-IL-5/5R drugs to dupilumab in severe eosinophilic asthma: A case series.

  • Authors : Poisson C; Service de Pneumologie et Soins Intensifs Respiratoire, Centre de Référence Constitutif des Maladies Pulmonaires Rares de l'Adultes de Dijon, Réseau OrphaLung, Filière RespiFil, Centre Hospitalier Universitaire de Bourgogne, Dijon, France; Inserm U1231, Equipe HSP-pathies, Faculty of Medicine and Pharmacy, University of Bourgogne-Franche Comté, Dijon, France.

Subjects: Anti-Asthmatic Agents*/Anti-Asthmatic Agents*/Anti-Asthmatic Agents*/therapeutic use ; Antibodies, Monoclonal, Humanized*/Antibodies, Monoclonal, Humanized*/Antibodies, Monoclonal, Humanized*/therapeutic use ; Asthma*/Asthma*/Asthma*/drug therapy

  • Source: The journal of allergy and clinical immunology. In practice [J Allergy Clin Immunol Pract] 2024 Jul; Vol. 12 (7), pp. 1914-1917. Date of Electronic Publication: 2024 Mar 27.Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101597220 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Targeting the IL-5 pathway in eosinophilic asthma: A comparison of anti-IL-5 versus anti-IL-5 receptor agents.

  • Authors : Jackson DJ; Guy's Severe Asthma Centre, Guy's and St Thomas' NHS Trust, London, UK.; School of Immunology & Microbial Sciences, King's College London, London, UK.

Subjects: Interleukin-5*/Interleukin-5*/Interleukin-5*/antagonists & inhibitors ; Interleukin-5*/Interleukin-5*/Interleukin-5*/metabolism ; Asthma*/Asthma*/Asthma*/drug therapy

  • Source: Allergy [Allergy] 2024 Nov; Vol. 79 (11), pp. 2943-2952. Date of Electronic Publication: 2024 Oct 12.Publisher: Wiley-Blackwell Country of Publication: Denmark NLM ID: 7804028 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Depemokimab, the first ultra-long-acting anti-IL-5 monoclonal antibody for severe eosinophilic asthma.

  • Authors : Nolasco S; Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy; Policlinico 'G. Rodolico - San Marco' University Hospital, Catania, Italy.

Subjects: Asthma*/Asthma*/Asthma*/drug therapy ; Asthma*/Asthma*/Asthma*/immunology ; Antibodies, Monoclonal, Humanized*/Antibodies, Monoclonal, Humanized*/Antibodies, Monoclonal, Humanized*/therapeutic use

  • Source: Med (New York, N.Y.) [Med] 2024 Dec 13; Vol. 5 (12), pp. 1452-1455.Publisher: Cell Press Country of Publication: United States NLM ID: 101769215 Publication Model: Print Cited Medium: Internet ISSN: 2666-6340

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Academic Journal

A Potential Role of Interleukin-5 in the Pathogenesis and Progression of Amyotrophic Lateral Sclerosis: A New Molecular Perspective.

  • Authors : Moțățăianu A; 1st Neurology Clinic, Mures County Clinical Emergency Hospital, 540136 Targu Mures, Romania.; Department of Neurology, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, 540142 Targu Mures, Romania.

Subjects: Amyotrophic Lateral Sclerosis* ; Interleukin-5*; Humans

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 28; Vol. 25 (7). Date of Electronic Publication: 2024 Mar 28.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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  • 1-10 of  33,256 results for ""Interleukin-5""