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Academic Journal

ALKBH5 deletion ameliorates inflammation by regulating IRF3 signaling in an m 6 A-dependent manner after myocardial infarction.

  • Authors : Zhao X; Institute of Clinical Pharmacology, The Second Affiliated Hospital of Harbin Medical University (National Key Laboratory of Frigid Cardiovascular Disease), 150081, Harbin, China.; Liang Z

Subjects: AlkB Homolog 5, RNA Demethylase*/AlkB Homolog 5, RNA Demethylase*/AlkB Homolog 5, RNA Demethylase*/metabolism ; AlkB Homolog 5, RNA Demethylase*/AlkB Homolog 5, RNA Demethylase*/AlkB Homolog 5, RNA Demethylase*/genetics ; Myocardial Infarction*/Myocardial Infarction*/Myocardial Infarction*/metabolism

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2025 Jan; Vol. 742, pp. 151039. Date of Electronic Publication: 2024 Nov 20.Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Chlamydia psittaci infection induces IFN-I and IL-1β through the cGAS-STING-IRF3/NLRP3 pathway via mitochondrial oxidative stress in human macrophages.

  • Authors : Yang H; Institute of Pathogenic Biology, Hengyang Medical College, University of South China, Hengyang, China.; Sun P

Subjects: Nucleotidyltransferases*/Nucleotidyltransferases*/Nucleotidyltransferases*/metabolism ; Nucleotidyltransferases*/Nucleotidyltransferases*/Nucleotidyltransferases*/genetics ; NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism

  • Source: Veterinary microbiology [Vet Microbiol] 2024 Dec; Vol. 299, pp. 110292. Date of Electronic Publication: 2024 Nov 16.Publisher: Elsevier Scientific Pub. Co Country of Publication: Netherlands NLM ID: 7705469 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

The nuclear localization signal of monkeypox virus protein P2 orthologue is critical for inhibition of IRF3-mediated innate immunity.

  • Authors : Jiao P; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, People's Republic of China.; Ma J

Subjects: Immunity, Innate* ; Interferon Regulatory Factor-3*/Interferon Regulatory Factor-3*/Interferon Regulatory Factor-3*/metabolism ; Interferon Regulatory Factor-3*/Interferon Regulatory Factor-3*/Interferon Regulatory Factor-3*/genetics

  • Source: Emerging microbes & infections [Emerg Microbes Infect] 2024 Dec; Vol. 13 (1), pp. 2372344. Date of Electronic Publication: 2024 Jul 06.Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101594885 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Crosstalk and Prospects of TBK1 in Inflammation.

  • Authors : Liu H; Laboratory of Molecular Genetics of Aging and Tumor, Medical School, Kunming University of Science and Technology, Kunming, China.; Sheng Q

Subjects: Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/metabolism ; Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/genetics ; Inflammation*/Inflammation*/Inflammation*/immunology

  • Source: Immunological investigations [Immunol Invest] 2024 Nov; Vol. 53 (8), pp. 1205-1233. Date of Electronic Publication: 2024 Aug 28.Publisher: Informa Healthcare Country of Publication: England NLM ID: 8504629 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

A new antibacterial with anti-inflammatory properties promotes wound healing through inhibiting cGAS/STING/NF-κB/IRF3 pathway.

  • Authors : Yao Z; School of Medicine, Anhui University of Science and Technology, Huainan 232001, China; Anhui Province Key Laboratory of Occupational Health, Anhui No.2 Provincial People's Hospital, Hefei 230041, China.

Subjects: Interferon Regulatory Factor-3*/Interferon Regulatory Factor-3*/Interferon Regulatory Factor-3*/metabolism ; NF-kappa B*/NF-kappa B*/NF-kappa B*/metabolism ; Membrane Proteins*/Membrane Proteins*/Membrane Proteins*/metabolism

  • Source: International immunopharmacology [Int Immunopharmacol] 2024 Dec 25; Vol. 143 (Pt 1), pp. 113303. Date of Electronic Publication: 2024 Oct 03.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

TRIM65 regulates innate immune signaling by enhancing K6-linked ubiquitination of IRF3 and its chromatin recruitment.

  • Authors : Fonseca D; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

Subjects: Interferon Regulatory Factor-3*/Interferon Regulatory Factor-3*/Interferon Regulatory Factor-3*/metabolism ; Immunity, Innate* ; Ubiquitination*

  • Source: Cell reports [Cell Rep] 2024 Dec 24; Vol. 43 (12), pp. 114960. Date of Electronic Publication: 2024 Nov 23.Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Targeting TRAF6/IRF3 axis to inhibit NF-κB-p65 nuclear translocation enhances the chemosensitivity of 5-FU and reverses the proliferation of gastric cancer.

  • Authors : Chen S; State Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing, 400715, China.; Chongqing Engineering and Technology Research Center for Silk Biomaterials and Regenerative Medicine, Chongqing, 400716, China.

Subjects: Stomach Neoplasms*/Stomach Neoplasms*/Stomach Neoplasms*/metabolism ; Stomach Neoplasms*/Stomach Neoplasms*/Stomach Neoplasms*/drug therapy ; Stomach Neoplasms*/Stomach Neoplasms*/Stomach Neoplasms*/pathology

  • Source: Cell death & disease [Cell Death Dis] 2024 Dec 20; Vol. 15 (12), pp. 924. Date of Electronic Publication: 2024 Dec 20.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Autophagy deficiency exacerbated hypoxia-reoxygenation induced inflammation and cell death via a mitochondrial DNA/STING/IRF3 pathway.

  • Authors : Tam E; Department of Biology, York University, Toronto, Canada.; Song E

Subjects: DNA, Mitochondrial*/DNA, Mitochondrial*/DNA, Mitochondrial*/metabolism ; DNA, Mitochondrial*/DNA, Mitochondrial*/DNA, Mitochondrial*/genetics ; Autophagy*

  • Source: Life sciences [Life Sci] 2024 Dec 01; Vol. 358, pp. 123173. Date of Electronic Publication: 2024 Oct 24.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0375521 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Targeting STING oligomerization with licochalcone D ameliorates STING-driven inflammatory diseases.

  • Authors : Zhang Y; Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.

Subjects: Chalcones*/Chalcones*/Chalcones*/chemistry ; Chalcones*/Chalcones*/Chalcones*/pharmacology ; Membrane Proteins*/Membrane Proteins*/Membrane Proteins*/metabolism

  • Source: Science China. Life sciences [Sci China Life Sci] 2024 Dec; Vol. 67 (12), pp. 2664-2677. Date of Electronic Publication: 2024 Aug 22.Publisher: Science China Press, co-published with Springer Country of Publication: China NLM ID: 101529880 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

The involvement of endogenous melatonin in LPS-induced M1-like macrophages and its underlying synthesis mechanism regulated by IRF3.

  • Authors : Chen X; School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China; Key Laboratory of Gastrointestinal Cancer (Fujian Medical University), Ministry of Education, Fuzhou, China.

Subjects: Melatonin*/Melatonin*/Melatonin*/pharmacology ; Lipopolysaccharides*/Lipopolysaccharides*/Lipopolysaccharides*/pharmacology ; Macrophages*/Macrophages*/Macrophages*/metabolism

  • Source: Experimental cell research [Exp Cell Res] 2024 Nov 01; Vol. 443 (1), pp. 114314. Date of Electronic Publication: 2024 Oct 30.Publisher: Academic Press Country of Publication: United States NLM ID: 0373226 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  4,915 results for ""Interferon Regulatory Factor-3""