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Academic Journal

IRS2 Signaling Protects Against Stress-Induced Arrhythmia by Maintaining Ca 2+ Homeostasis.

  • Authors : Shi Q; Department of Internal Medicine (Q.S., J.W., H.M., X.L., J. Streeter, J. Sharafuddin, E.W., B.C., D.H., L.-S.S., E.D.A.), Carver College of Medicine, University of Iowa, Iowa City.; Wang J

Subjects: Insulin Receptor Substrate Proteins*/Insulin Receptor Substrate Proteins*/Insulin Receptor Substrate Proteins*/metabolism ; Insulin Receptor Substrate Proteins*/Insulin Receptor Substrate Proteins*/Insulin Receptor Substrate Proteins*/genetics ; Ryanodine Receptor Calcium Release Channel*/Ryanodine Receptor Calcium Release Channel*/Ryanodine Receptor Calcium Release Channel*/metabolism

  • Source: Circulation [Circulation] 2024 Dec 10; Vol. 150 (24), pp. 1966-1983. Date of Electronic Publication: 2024 Sep 10.Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0147763 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

AKT1-Mediated NOTCH1 phosphorylation promotes gastric cancer progression via targeted regulation of IRS-1 transcription.

  • Authors : Zhou L; The First Clinical Medical College, Lanzhou University, Lanzhou, 730000, China.; Department of Gastroenterology, The First Hospital of Lanzhou University, Lanzhou, 730000, China.

Subjects: Stomach Neoplasms*/Stomach Neoplasms*/Stomach Neoplasms*/pathology ; Stomach Neoplasms*/Stomach Neoplasms*/Stomach Neoplasms*/metabolism ; Stomach Neoplasms*/Stomach Neoplasms*/Stomach Neoplasms*/genetics

  • Source: Journal of cancer research and clinical oncology [J Cancer Res Clin Oncol] 2024 Dec 26; Vol. 151 (1), pp. 15. Date of Electronic Publication: 2024 Dec 26.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 7902060 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1335

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Academic Journal

Assessment of Changes in the Expression of Genes Involved in Insulin Signaling and Glucose Transport in Leukocytes of Women with Gestational Diabetes During Pregnancy and in the Postpartum Period.

  • Authors : Zieleniak A; Department of Structural Biology, Faculty of Biomedical Sciences, Medical University of Lodz, 90-752 Lodz, Poland.; Zurawska-Klis M

Subjects: Diabetes, Gestational*/Diabetes, Gestational*/Diabetes, Gestational*/metabolism ; Diabetes, Gestational*/Diabetes, Gestational*/Diabetes, Gestational*/genetics ; Diabetes, Gestational*/Diabetes, Gestational*/Diabetes, Gestational*/blood

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Dec 05; Vol. 25 (23). Date of Electronic Publication: 2024 Dec 05.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Andrographis paniculata (Burm. f.) Nees extract ameliorates insulin resistance in the insulin-resistant HepG2 cells via GLUT2/IRS-1 pathway.

  • Authors : Ningsih S; Research Center for Pharmaceutical Ingredients and Traditional Medicine, National Research and Innovation Agency (BRIN) Republic of Indonesia, LAPTIAB Building 610-614, Puspiptek Area, South Tangerang, Indonesia.; Kusumastuti SA

Subjects: Insulin Receptor Substrate Proteins*/Insulin Receptor Substrate Proteins*/Insulin Receptor Substrate Proteins*/metabolism ; Insulin Receptor Substrate Proteins*/Insulin Receptor Substrate Proteins*/Insulin Receptor Substrate Proteins*/genetics ; Insulin Resistance*

  • Source: Archives of physiology and biochemistry [Arch Physiol Biochem] 2024 Dec; Vol. 130 (6), pp. 779-789. Date of Electronic Publication: 2023 Oct 25.Publisher: Informa Healthcare Country of Publication: England NLM ID: 9510153 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

ASPSCR1::TFE3-mediated upregulation of insulin receptor substrate 2 (IRS-2) activates PI3K/AKT signaling and promotes malignant phenotype.

  • Authors : Ishiguro N; Department of Pathobiological Science and Technology, Faculty of Medicine, Tottori University, Yonago, Japan. Electronic address: .; Nakagawa M

Subjects: Insulin Receptor Substrate Proteins*/Insulin Receptor Substrate Proteins*/Insulin Receptor Substrate Proteins*/metabolism ; Insulin Receptor Substrate Proteins*/Insulin Receptor Substrate Proteins*/Insulin Receptor Substrate Proteins*/genetics ; Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/metabolism

  • Source: The international journal of biochemistry & cell biology [Int J Biochem Cell Biol] 2024 Nov; Vol. 176, pp. 106676. Date of Electronic Publication: 2024 Oct 16.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9508482 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Fluorescent tagging of endogenous IRS2 with an auxin-dependent degron to assess dynamic intracellular localization and function.

  • Authors : Jo M; Department of Molecular, Cell & Cancer Biology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.; Lee JS

Subjects: Insulin Receptor Substrate Proteins*/Insulin Receptor Substrate Proteins*/Insulin Receptor Substrate Proteins*/metabolism ; Insulin Receptor Substrate Proteins*/Insulin Receptor Substrate Proteins*/Insulin Receptor Substrate Proteins*/genetics ; Indoleacetic Acids*/Indoleacetic Acids*/Indoleacetic Acids*/metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2024 Nov; Vol. 300 (11), pp. 107796. Date of Electronic Publication: 2024 Sep 19.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Schisandra chinensis lignans improve insulin resistance by targeting TLR4 and activating IRS-1/PI3K/AKT and NF-κB signaling pathways.

  • Authors : Zhao SL; School of Medical Technology, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.; Liu D

Subjects: Toll-Like Receptor 4*/Toll-Like Receptor 4*/Toll-Like Receptor 4*/metabolism ; Insulin Receptor Substrate Proteins*/Insulin Receptor Substrate Proteins*/Insulin Receptor Substrate Proteins*/metabolism ; Schisandra*/Schisandra*/Schisandra*/chemistry

  • Source: International immunopharmacology [Int Immunopharmacol] 2024 Dec 05; Vol. 142 (Pt A), pp. 113069. Date of Electronic Publication: 2024 Sep 05.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Insulin receptor substrate 1 is a novel member of EGFR signaling in pancreatic cells.

  • Authors : Takács T; Institute of Molecular Life Sciences, HUN-REN Research Centre for Natural Sciences, Budapest 1117, Hungary; Doctoral School of Biology, Institute of Biology, ELTE Eötvös Loránd University, Budapest 1117, Hungary.

Subjects: ErbB Receptors*/ErbB Receptors*/ErbB Receptors*/metabolism ; Insulin Receptor Substrate Proteins*/Insulin Receptor Substrate Proteins*/Insulin Receptor Substrate Proteins*/metabolism ; Signal Transduction*

  • Source: European journal of cell biology [Eur J Cell Biol] 2024 Dec; Vol. 103 (4), pp. 151457. Date of Electronic Publication: 2024 Sep 18.Publisher: Elsevier Country of Publication: Germany NLM ID: 7906240 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-1298

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Academic Journal

Lactobacillus reuteri TISTR 2736 alleviates type 2 diabetes in rats via the hepatic IRS1/PI3K/AKT signaling pathway by mitigating oxidative stress and inflammatory mediators.

  • Authors : Pakaew K; Department of Physiology, Faculty of Medical Science, Naresuan University, Phitsanulok, 65000, Thailand.; Chonpathompikunlert P

Subjects: Limosilactobacillus reuteri*/Limosilactobacillus reuteri*/Limosilactobacillus reuteri*/physiology ; Oxidative Stress* ; Insulin Receptor Substrate Proteins*/Insulin Receptor Substrate Proteins*/Insulin Receptor Substrate Proteins*/metabolism

  • Source: European journal of nutrition [Eur J Nutr] 2024 Nov 26; Vol. 64 (1), pp. 27. Date of Electronic Publication: 2024 Nov 26.Publisher: Steinkopff Country of Publication: Germany NLM ID: 100888704 Publication Model: Electronic Cited Medium: Internet ISSN: 1436-6215

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Academic Journal

Buparlisib and ponatinib inhibit aggressiveness of cholangiocarcinoma cells via suppression of IRS1-related pathway by targeting oxidative stress resistance.

  • Authors : Kaewlert W; Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.; Sakonsinsiri C

Subjects: Cholangiocarcinoma*/Cholangiocarcinoma*/Cholangiocarcinoma*/drug therapy ; Cholangiocarcinoma*/Cholangiocarcinoma*/Cholangiocarcinoma*/pathology ; Cholangiocarcinoma*/Cholangiocarcinoma*/Cholangiocarcinoma*/metabolism

  • Source: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Nov; Vol. 180, pp. 117569. Date of Electronic Publication: 2024 Oct 17.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet

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  • 1-10 of  7,916 results for ""Insulin Receptor Substrate Proteins""