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Academic Journal

Lower micromolar activity of the antifungal imidazoles on the bacterial-type bifunctional aldehyde/alcohol dehydrogenase (AdhE) in Cryptosporidium parvum and in vitro efficacy against the zoonotic parasite.

  • Authors : Chen H; College of Veterinary Medicine, China Agricultural University, Haidian District, Beijing, 100193, China. Electronic address: .; Wang D

Subjects: Cryptosporidium parvum*/Cryptosporidium parvum*/Cryptosporidium parvum*/drug effects ; Cryptosporidium parvum*/Cryptosporidium parvum*/Cryptosporidium parvum*/enzymology ; Imidazoles*/Imidazoles*/Imidazoles*/pharmacology

  • Source: International journal for parasitology. Drugs and drug resistance [Int J Parasitol Drugs Drug Resist] 2024 Aug; Vol. 25, pp. 100551. Date of Electronic Publication: 2024 Jun 06.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101576715 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Imidazoles are Tunable Nucleofuges for Developing Tyrosine-Reactive Electrophiles.

  • Authors : Justin Grams R; Department of Chemistry, University of Texas at Austin, 100 E 24th St, Texas, 78712, United States.; Yuan K

Subjects: Imidazoles*/Imidazoles*/Imidazoles*/chemistry ; Imidazoles*/Imidazoles*/Imidazoles*/chemical synthesis ; Tyrosine*/Tyrosine*/Tyrosine*/chemistry

  • Source: Chembiochem : a European journal of chemical biology [Chembiochem] 2024 Aug 19; Vol. 25 (16), pp. e202400382. Date of Electronic Publication: 2024 Jul 18.Publisher: Wiley-VCH Verlag Country of Publication: Germany NLM ID: 100937360 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Iodide enhances degradation of histidine sidechain and imidazoles and forms new iodinated aromatic disinfection byproducts during chlorination.

  • Authors : Choi SY; Department of Civil and Environmental Engineering and Institute of Construction and Environmental Engineering, Seoul National University, Seoul, the Republic of Korea.; Ji H

Subjects: Imidazoles*/Imidazoles*/Imidazoles*/chemistry ; Histidine*/Histidine*/Histidine*/chemistry ; Disinfection*

  • Source: Journal of hazardous materials [J Hazard Mater] 2024 Aug 05; Vol. 474, pp. 134748. Date of Electronic Publication: 2024 May 27.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9422688 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Prolonged Skin Retention of Luliconazole from SLNs Based Topical Gel Formulation Contributing to Ameliorated Antifungal Activity.

  • Authors : Kaur M; Department of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, Punjab, 143005, India.; Singh G

Subjects: Antifungal Agents*/Antifungal Agents*/Antifungal Agents*/administration & dosage ; Antifungal Agents*/Antifungal Agents*/Antifungal Agents*/pharmacokinetics ; Antifungal Agents*/Antifungal Agents*/Antifungal Agents*/pharmacology

  • Source: AAPS PharmSciTech [AAPS PharmSciTech] 2024 Oct 01; Vol. 25 (7), pp. 229. Date of Electronic Publication: 2024 Oct 01.Publisher: Springer Country of Publication: United States NLM ID: 100960111 Publication Model: Electronic Cited Medium: Internet ISSN: 1530-9932

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Academic Journal

Poly (ADP-ribose) polymerase inhibitor sensitized DNA damage caused by an alkylating pyrrole-imidazole polyamide targeting MYCN in neuroblastoma cells.

  • Authors : Lai X; Division of Innovative Cancer Therapeutics, Chiba Cancer Center Research Institute, Chiba, Japan; Graduate School of Medical and Pharmaceutical Sciences, Chiba University, Chiba, Japan.

Subjects: Neuroblastoma*/Neuroblastoma*/Neuroblastoma*/pathology ; Neuroblastoma*/Neuroblastoma*/Neuroblastoma*/drug therapy ; Neuroblastoma*/Neuroblastoma*/Neuroblastoma*/metabolism

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2024 Nov 26; Vol. 735, pp. 150794. Date of Electronic Publication: 2024 Oct 09.Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Synthesis, pharmacological evaluation, and modeling of novel quaternary ammonium salts derived from β-carboline containing an imidazole moiety as angiogenesis inhibitors.

  • Authors : Chen S; School of Chemistry and Chemical Engineering, Key Laboratory for Green Processing of Chemical Engineering of Xinjiang Bingtuan, Shihezi University, Shihezi 832003, PR China.; Chen X

Subjects: Carbolines*/Carbolines*/Carbolines*/chemistry ; Carbolines*/Carbolines*/Carbolines*/pharmacology ; Carbolines*/Carbolines*/Carbolines*/chemical synthesis

  • Source: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2024 Nov 15; Vol. 114, pp. 117946. Date of Electronic Publication: 2024 Oct 09.Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Design, synthesis, and biological evaluation of imidazolylacetophenone oxime derivatives as novel brain-penetrant agents for Alzheimer's disease treatment.

  • Authors : Bian ZY; Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University, No.3 Taicheng Road, Yangling, Shaanxi, 712100, China.; Li PX

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/drug therapy ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism ; Oximes*/Oximes*/Oximes*/chemistry

  • Source: European journal of medicinal chemistry [Eur J Med Chem] 2024 Nov 15; Vol. 278, pp. 116794. Date of Electronic Publication: 2024 Aug 30.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Final Results for Adjuvant Dabrafenib plus Trametinib in Stage III Melanoma.

  • Authors : Long GV; From the Melanoma Institute Australia, the University of Sydney, Royal North Shore Hospital, and Mater Hospital, Sydney (G.V.L.), Princess Alexandra Hospital, the Gallipoli Medical Research Foundation, and the University of Queensland, Woolloongabba (V.A.), and Alfred Hospital, Melbourne, VIC (A.H.) - all in Australia; the Department of Dermatology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel (A.H.), and the German Cancer Consortium, National Center for Tumor Diseases, University Hospital Essen, Campus Essen, and the University Alliance Ruhr, Research Center One Health, University of Duisburg-Essen, Essen (D.S.) - all in Germany

Subjects: Antineoplastic Combined Chemotherapy Protocols*/Antineoplastic Combined Chemotherapy Protocols*/Antineoplastic Combined Chemotherapy Protocols*/administration & dosage ; Antineoplastic Combined Chemotherapy Protocols*/Antineoplastic Combined Chemotherapy Protocols*/Antineoplastic Combined Chemotherapy Protocols*/adverse effects ; Imidazoles*/Imidazoles*/Imidazoles*/administration & dosage

  • Source: The New England journal of medicine [N Engl J Med] 2024 Nov 07; Vol. 391 (18), pp. 1709-1720. Date of Electronic Publication: 2024 Jun 19.Publisher: Massachusetts Medical Society Country of Publication: United States NLM ID: 0255562 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

A guanidiniocarbonyl-pyrrole functionalized cucurbit[7]uril derivative as a cytomembrane disruptor for synergistic antibacterial therapy.

  • Authors : Han R; College of Materials Science and Technology, Nanjing University of Aeronautics and Astronautics, Nanjing 211106, China. .; Du K

Subjects: Anti-Bacterial Agents*/Anti-Bacterial Agents*/Anti-Bacterial Agents*/pharmacology ; Anti-Bacterial Agents*/Anti-Bacterial Agents*/Anti-Bacterial Agents*/chemistry ; Anti-Bacterial Agents*/Anti-Bacterial Agents*/Anti-Bacterial Agents*/chemical synthesis

  • Source: Journal of materials chemistry. B [J Mater Chem B] 2024 Nov 06; Vol. 12 (43), pp. 11105-11109. Date of Electronic Publication: 2024 Nov 06.Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101598493 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Emerging therapeutics: The imidazo[1,2-b]pyridazine scaffold as a novel drug candidate for eumycetoma, a neglected tropical disease.

  • Authors : Elkheir LYM; The Mycetoma Research Center, University of Khartoum, Khartoum, Sudan; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Khartoum, Sudan

Subjects: Pyridazines*/Pyridazines*/Pyridazines*/pharmacology ; Pyridazines*/Pyridazines*/Pyridazines*/chemistry ; Pyridazines*/Pyridazines*/Pyridazines*/chemical synthesis

  • Source: European journal of medicinal chemistry [Eur J Med Chem] 2024 Nov 05; Vol. 277, pp. 116720. Date of Electronic Publication: 2024 Jul 26.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet

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  • 1-10 of  128,923 results for ""Imidazoles""