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  • 1-10 of  2,195 results for ""Hepatocyte Nuclear Factor 1-alpha""

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Academic Journal

Castrate-resistant prostate cancer response to taxane is determined by an HNF1-dependent apoptosis resistance circuit.

  • Authors : Senatorov IS; Laboratory of Genitourinary Cancer Pathogenesis, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA.; Bowman J

Subjects: Taxoids*/Taxoids*/Taxoids*/pharmacology ; Taxoids*/Taxoids*/Taxoids*/therapeutic use ; Prostatic Neoplasms, Castration-Resistant*/Prostatic Neoplasms, Castration-Resistant*/Prostatic Neoplasms, Castration-Resistant*/drug therapy

  • Source: Cell reports. Medicine [Cell Rep Med] 2024 Dec 17; Vol. 5 (12), pp. 101868. Date of Electronic Publication: 2024 Dec 09.Publisher: Cell Press Country of Publication: United States NLM ID: 101766894 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

HNF1ɑ promotes colorectal cancer progression via HKDC1-mediated activation of AKT/AMPK signaling pathway.

  • Authors : Yang W; Department of Colorectal Surgery, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, Fujian 350014, China; Fujian Medical University, Fuzhou, Fujian 350122, China.

Subjects: Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/genetics ; Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/metabolism ; Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/pathology

  • Source: Gene [Gene] 2024 Nov 30; Vol. 928, pp. 148752. Date of Electronic Publication: 2024 Jul 08.Publisher: Elsevier/North-Holland Country of Publication: Netherlands NLM ID: 7706761 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Prognostic significance of CD8 and TCF1 double positive T cell subset in microsatellite unstable gastric cancer.

  • Authors : Park J; Seoul National University College of Medicine, Seoul, Korea.; Nam SK

Subjects: Stomach Neoplasms*/Stomach Neoplasms*/Stomach Neoplasms*/genetics ; Stomach Neoplasms*/Stomach Neoplasms*/Stomach Neoplasms*/immunology ; Stomach Neoplasms*/Stomach Neoplasms*/Stomach Neoplasms*/pathology

  • Source: Scientific reports [Sci Rep] 2024 Nov 21; Vol. 14 (1), pp. 28810. Date of Electronic Publication: 2024 Nov 21.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Transcription factor TCF1 binds to RORγt and orchestrates a regulatory network that determines homeostatic Th17 cell state.

  • Authors : Mangani D; Gene Lay Institute of Immunology and Inflammation, Ann Romney Center for Neurologic Diseases, Harvard Medical School and Mass General Brigham, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA

Subjects: Th17 Cells*/Th17 Cells*/Th17 Cells*/immunology ; Th17 Cells*/Th17 Cells*/Th17 Cells*/metabolism ; Nuclear Receptor Subfamily 1, Group F, Member 3*/Nuclear Receptor Subfamily 1, Group F, Member 3*/Nuclear Receptor Subfamily 1, Group F, Member 3*/metabolism

  • Source: Immunity [Immunity] 2024 Nov 12; Vol. 57 (11), pp. 2565-2582.e6. Date of Electronic Publication: 2024 Oct 23.Publisher: Cell Press Country of Publication: United States NLM ID: 9432918 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Autoimmune CD4 + T cells fine-tune TCF1 expression to maintain function and survive persistent antigen exposure during diabetes.

  • Authors : Aljobaily N; Department of Pathology, Division of Microbiology and Immunology, University of Utah, Salt Lake City, UT 84112, USA.; Allard D

Subjects: CD4-Positive T-Lymphocytes*/CD4-Positive T-Lymphocytes*/CD4-Positive T-Lymphocytes*/immunology ; Hepatocyte Nuclear Factor 1-alpha*/Hepatocyte Nuclear Factor 1-alpha*/Hepatocyte Nuclear Factor 1-alpha*/metabolism ; Hepatocyte Nuclear Factor 1-alpha*/Hepatocyte Nuclear Factor 1-alpha*/Hepatocyte Nuclear Factor 1-alpha*/genetics

  • Source: Immunity [Immunity] 2024 Nov 12; Vol. 57 (11), pp. 2583-2596.e6. Date of Electronic Publication: 2024 Oct 12.Publisher: Cell Press Country of Publication: United States NLM ID: 9432918 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Acetylcysteine synergizes PD-1 blockers against colorectal cancer progression by promoting TCF1 + PD1 + CD8 + T cell differentiation.

  • Authors : Zhou W; Department of Anesthesiology, Zhongshan Hospital, Cancer Center, Zhongshan Hospital, Fudan University, Fudan University, 180# Feng-Lin Road, Shanghai, 200032, China.; Shanghai Key Laboratory of Perioperative Stress and Protection, Shanghai, China.

Subjects: Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/pathology ; Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/drug therapy ; Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/immunology

  • Source: Cell communication and signaling : CCS [Cell Commun Signal] 2024 Oct 17; Vol. 22 (1), pp. 503. Date of Electronic Publication: 2024 Oct 17.Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X

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Academic Journal

Loss of ARID3A perturbs intestinal epithelial proliferation-differentiation ratio and regeneration.

  • Authors : Angelis N; Stem Cell and Cancer Biology Laboratory, The Francis Crick Institute , London, UK.; Baulies A

Subjects: Cell Proliferation* ; Cell Differentiation* ; Intestinal Mucosa*/Intestinal Mucosa*/Intestinal Mucosa*/metabolism

  • Source: The Journal of experimental medicine [J Exp Med] 2024 Oct 07; Vol. 221 (10). Date of Electronic Publication: 2024 Aug 16.Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985109R Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Protective effects of cilostazol via the HNF1α/FXR signalling pathway and anti-apoptotic mechanisms in a rat model of estrogen-induced intrahepatic cholestasis.

  • Authors : Hassan M; Immunology Department, Theodor Bilharz Research Institute, Warrak El-Hadar, P.O. box 30, Imbaba, 12411, Giza, Egypt.; Salem MB

Subjects: Signal Transduction*/Signal Transduction*/Signal Transduction*/drug effects ; Apoptosis*/Apoptosis*/Apoptosis*/drug effects ; Hepatocyte Nuclear Factor 1-alpha*/Hepatocyte Nuclear Factor 1-alpha*/Hepatocyte Nuclear Factor 1-alpha*/metabolism

  • Source: Scientific reports [Sci Rep] 2024 Oct 01; Vol. 14 (1), pp. 22751. Date of Electronic Publication: 2024 Oct 01.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Genetic insights into fetal kidney development: Variants in HNF1A and PKHD1 genes.

  • Authors : Abdelwahed M; Laboratory of Human Molecular Genetics, Faculty of Medecine of Sfax, University of Sfax, Tunisia. Electronic address: .; Benoit V

Subjects: Polymorphism, Single Nucleotide* ; Kidney*/Kidney*/Kidney*/metabolism ; Kidney*/Kidney*/Kidney*/embryology

  • Source: Gene [Gene] 2024 Nov 15; Vol. 927, pp. 148625. Date of Electronic Publication: 2024 Jun 01.Publisher: Elsevier/North-Holland Country of Publication: Netherlands NLM ID: 7706761 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Clinical characteristics, treatment, and treatment switch after molecular-genetic classification in individuals with maturity-onset diabetes of the young: Insights from the multicenter real-world DPV registry.

  • Authors : Lanzinger S; Institute of Epidemiology and Medical Biometry, CAQM, Ulm University, Ulm, Germany.; Munich-Neuherberg, German Center for Diabetes Research (DZD), Munich, Germany.

Subjects: Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/genetics ; Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/drug therapy ; Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/diagnosis Mason-Type Diabetes

  • Source: Journal of diabetes [J Diabetes] 2024 Nov; Vol. 16 (11), pp. e70028.Publisher: Blackwell Publishing Asia Country of Publication: Australia NLM ID: 101504326 Publication Model: Print Cited Medium: Internet ISSN:

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  • 1-10 of  2,195 results for ""Hepatocyte Nuclear Factor 1-alpha""