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Academic Journal

Novel combinatorial approach: Harnessing HIV protease inhibitors to enhance amphotericin B's antifungal efficacy in cryptococcosis.

  • Authors : Alkashef NM; Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States of America.; Center for One Health Research, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States of America.

Subjects: Amphotericin B*/Amphotericin B*/Amphotericin B*/pharmacology ; Amphotericin B*/Amphotericin B*/Amphotericin B*/therapeutic use ; Antifungal Agents*/Antifungal Agents*/Antifungal Agents*/pharmacology

  • Source: PloS one [PLoS One] 2024 Aug 01; Vol. 19 (8), pp. e0308216. Date of Electronic Publication: 2024 Aug 01 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Susceptibility of HPV-18 Cancer Cells to HIV Protease Inhibitors.

  • Authors : Makgoo L; Department of Biochemistry, Microbiology and Biotechnology, University of Limpopo, Private Bag X 1106, Sovenga, Polokwane 0727, South Africa.; Mosebi S

Subjects: HIV Protease Inhibitors*/HIV Protease Inhibitors*/HIV Protease Inhibitors*/pharmacology ; Uterine Cervical Neoplasms*/Uterine Cervical Neoplasms*/Uterine Cervical Neoplasms*/virology ; Uterine Cervical Neoplasms*/Uterine Cervical Neoplasms*/Uterine Cervical Neoplasms*/drug therapy

  • Source: Viruses [Viruses] 2024 Oct 17; Vol. 16 (10). Date of Electronic Publication: 2024 Oct 17.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915

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Academic Journal

HIV-protease inhibitors potentiate the activity of carfilzomib in triple-negative breast cancer.

  • Authors : Besse A; Laboratory of Experimental Oncology, Department of Oncology and Hematology, Cantonal Hospital St. Gallen, St. Gallen, 9000, Switzerland.; Department of Biology, Faculty of Medicine, Masaryk University, Brno, 62500, Czech Republic.

Subjects: Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/drug therapy ; Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/pathology ; Oligopeptides*/Oligopeptides*/Oligopeptides*/pharmacology

  • Source: British journal of cancer [Br J Cancer] 2024 Sep; Vol. 131 (5), pp. 918-930. Date of Electronic Publication: 2024 Jul 05.Publisher: Nature Publishing Group on behalf of Cancer Research UK Country of Publication: England NLM ID: 0370635 Publication Model: Print-Electronic Cited

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Academic Journal

Structural and Functional Studies on HIV Protease: Mechanism of Action, Subtypes, Inhibitors, and Drug Resistance.

  • Authors : Venkatachalam S; Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences, Indian Institute of Technology Madras, Chennai, Tamil Nadu, India.; Krishnan SR

Subjects: HIV Protease*/HIV Protease*/HIV Protease*/metabolism ; HIV Protease*/HIV Protease*/HIV Protease*/chemistry ; Drug Resistance, Viral*

  • Source: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2025; Vol. 2867, pp. 185-200.Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029

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Academic Journal

Triterpene esters from Uncaria rhynchophylla hooks as potent HIV-1 protease inhibitors and their molecular docking study.

  • Authors : Lee J; Department of Pharmacognosy, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, Korea. .

Subjects: Triterpenes*/Triterpenes*/Triterpenes*/chemistry ; Triterpenes*/Triterpenes*/Triterpenes*/pharmacology ; Molecular Docking Simulation*

  • Source: Scientific reports [Sci Rep] 2024 Dec 30; Vol. 14 (1), pp. 31576. Date of Electronic Publication: 2024 Dec 30.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Contrasting the effect of hinge region insertions and non-active site mutations on HIV protease-inhibitor interactions: Insights from altered flap dynamics.

  • Authors : Mokhantso T; Protein Structure-Function Research Unit, School of Molecular and Cell Biology, University of the Witwatersrand, Johannesburg, 2050, South Africa.; Sherry D

Subjects: HIV Protease*/HIV Protease*/HIV Protease*/chemistry ; HIV Protease*/HIV Protease*/HIV Protease*/genetics ; HIV Protease*/HIV Protease*/HIV Protease*/metabolism

  • Source: Journal of molecular graphics & modelling [J Mol Graph Model] 2024 Dec; Vol. 133, pp. 108850. Date of Electronic Publication: 2024 Aug 29.Publisher: Elsevier Science, Inc Country of Publication: United States NLM ID: 9716237 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Enhanced antifungal activity of posaconazole against Candida auris by HIV protease inhibitors, atazanavir and saquinavir.

  • Authors : Elgammal Y; Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, 1410 Prices Fork Rd, Blacksburg, VA, 24061, USA.; Center for One Health Research, Virginia Polytechnic Institute and State University, Blacksburg, VA, 24061, USA.

Subjects: HIV Protease Inhibitors*/HIV Protease Inhibitors*/HIV Protease Inhibitors*/pharmacology ; Candidiasis, Invasive*/Candidiasis, Invasive*/Candidiasis, Invasive*/drug therapy ; Triazoles*

  • Source: Scientific reports [Sci Rep] 2024 Jan 18; Vol. 14 (1), pp. 1571. Date of Electronic Publication: 2024 Jan 18.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Quantum mechanical analysis of newly synthesized HIV-1 protease inhibitors: evaluation of wild-type and resistant strain binding interactions.

  • Authors : Silva GVR; Departamento de Biofísica e Farmacologia, Universidade Federal do Rio Grande no Norte, 59072-970, Natal-RN, Brazil. .; Ramos Reiniger KA

Subjects: HIV Protease Inhibitors*/HIV Protease Inhibitors*/HIV Protease Inhibitors*/chemistry ; HIV Protease Inhibitors*/HIV Protease Inhibitors*/HIV Protease Inhibitors*/pharmacology ; HIV Protease Inhibitors*/HIV Protease Inhibitors*/HIV Protease Inhibitors*/metabolism

  • Source: Physical chemistry chemical physics : PCCP [Phys Chem Chem Phys] 2024 Oct 30; Vol. 26 (42), pp. 26748-26764. Date of Electronic Publication: 2024 Oct 30.Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 100888160 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Design of substituted tetrahydrofuran derivatives for HIV-1 protease inhibitors: synthesis, biological evaluation, and X-ray structural studies.

  • Authors : Ghosh AK; Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, IN 47907, USA. .; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, 560 Oval Drive, West Lafayette, IN 47907, USA.

Subjects: Furans*/Furans*/Furans*/chemistry ; Furans*/Furans*/Furans*/pharmacology ; Furans*/Furans*/Furans*/chemical synthesis

  • Source: Organic & biomolecular chemistry [Org Biomol Chem] 2024 Sep 18; Vol. 22 (36), pp. 7354-7372. Date of Electronic Publication: 2024 Sep 18.Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101154995 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Inhibition of human DNA alkylation damage repair enzyme ALKBH2 by HIV protease inhibitor ritonavir.

  • Authors : Shaji UP; Department of Biotechnology, Indian Institute of Technology Hyderabad (IITH), Kandi, Sanga Reddy, Telangana 502284, India.; Tuti N

Subjects: DNA Repair* ; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase*/AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase*/AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase*/metabolism ; Ritonavir*/Ritonavir*/Ritonavir*/pharmacology

  • Source: DNA repair [DNA Repair (Amst)] 2024 Sep; Vol. 141, pp. 103732. Date of Electronic Publication: 2024 Jul 25.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101139138 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  38,916 results for ""HIV Protease Inhibitors""