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Academic Journal

Fructose-1,6-bisphosphatase 1 dephosphorylates and inhibits TERT for tumor suppression.

  • Authors : Li M; Zhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital and Institute of Translational Medicine, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, China.; Cancer Center, Zhejiang University, Hangzhou, China.

Subjects: Telomerase*/Telomerase*/Telomerase*/metabolism ; Telomerase*/Telomerase*/Telomerase*/genetics ; Telomerase*/Telomerase*/Telomerase*/antagonists & inhibitors

  • Source: Nature chemical biology [Nat Chem Biol] 2024 Nov; Vol. 20 (11), pp. 1505-1513. Date of Electronic Publication: 2024 Mar 27.Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Discovery of novel fructose-1,6-bisphosphatase inhibitors bearing benzimidazole scaffold using a dual-ligand molecular docking model.

  • Authors : Wang H; Beijing Key Laboratory of Active Substance Discovery and Druggability Evaluation, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, 1 Xian Nong Tan Street, Beijing 100050, China.; Lei L

Subjects: Fructose-Bisphosphatase*/Fructose-Bisphosphatase*/Fructose-Bisphosphatase*/antagonists & inhibitors ; Fructose-Bisphosphatase*/Fructose-Bisphosphatase*/Fructose-Bisphosphatase*/metabolism ; Benzimidazoles*/Benzimidazoles*/Benzimidazoles*/chemistry

  • Source: European journal of medicinal chemistry [Eur J Med Chem] 2024 Dec 05; Vol. 279, pp. 116888. Date of Electronic Publication: 2024 Sep 19.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Structure-Guided Design of Affinity/Covalent-Bond Dual-Driven Inhibitors Targeting the AMP Site of FBPase.

  • Authors : Cao H; State Key Laboratory of Green Pesticide, College of Chemistry, Central China Normal University, Wuhan 430079, China.; Huang Z

Subjects: Fructose-Bisphosphatase*/Fructose-Bisphosphatase*/Fructose-Bisphosphatase*/antagonists & inhibitors ; Fructose-Bisphosphatase*/Fructose-Bisphosphatase*/Fructose-Bisphosphatase*/metabolism ; Fructose-Bisphosphatase*/Fructose-Bisphosphatase*/Fructose-Bisphosphatase*/chemistry

  • Source: Journal of medicinal chemistry [J Med Chem] 2024 Nov 28; Vol. 67 (22), pp. 20421-20437. Date of Electronic Publication: 2024 Nov 09.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Herbacetin Inhibits Human Fructose 1,6-Bisphosphatase Among a Panel of Chromone Derivatives and Pyrazoles, Demonstrating Positive Effects on Insulin-Resistant HepG2 Cells.

  • Authors : Rocha S; LAQV, REQUIMTE, Laboratory of Applied Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Porto, Portugal.; Vicente B

Subjects: Chromones*/Chromones*/Chromones*/pharmacology ; Chromones*/Chromones*/Chromones*/chemistry ; Insulin Resistance*

  • Source: Chemical biology & drug design [Chem Biol Drug Des] 2024 Nov; Vol. 104 (5), pp. e70017.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101262549 Publication Model: Print Cited Medium: Internet ISSN: 1747-0285

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Academic Journal

Cytosolic fructose-1,6-bisphosphatase isoform mediates metabolic adjustments in bean fruit pericarp to support seed growth.

  • Authors : Bernal L; Departamento de Bioquímica, Facultad de Química-Universidad Nacional Autónoma de México, CDMX, México.; Coello P

Subjects: Seeds*/Seeds*/Seeds*/growth & development ; Seeds*/Seeds*/Seeds*/metabolism ; Seeds*/Seeds*/Seeds*/genetics

  • Source: Physiologia plantarum [Physiol Plant] 2024 Nov-Dec; Vol. 176 (6), pp. e14631.Publisher: Scandinavian Society For Plant Physiology Country of Publication: Denmark NLM ID: 1256322 Publication Model: Print Cited Medium: Internet

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Academic Journal

Overexpression of FBP1 enhances dendritic cell activation and maturation by inhibiting glycolysis and promoting the secretion of IL33 in lung adenocarcinoma.

  • Authors : Li C; National Engineering Laboratory for Internet Medical Systems and Applications, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan, China; Department of Pharmacy, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan, China.

Subjects: Dendritic Cells*/Dendritic Cells*/Dendritic Cells*/metabolism ; Dendritic Cells*/Dendritic Cells*/Dendritic Cells*/immunology ; Glycolysis*

  • Source: Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2025 Jan; Vol. 1871 (1), pp. 167559. Date of Electronic Publication: 2024 Oct 30.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731730 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Neuronal extracellular vesicles influence the expression, degradation and oligomeric state of fructose 1,6-bisphosphatase 2 in astrocytes affecting their glycolytic capacity.

  • Authors : Hajka D; Department of Molecular Physiology and Neurobiology, University of Wrocław, 50-335, Wrocław, Poland.; Łukasiewicz Research Network - PORT Polish Center for Technology Development, 54-006, Wrocław, Poland.

Subjects: Astrocytes*/Astrocytes*/Astrocytes*/metabolism ; Glycolysis* ; Extracellular Vesicles*/Extracellular Vesicles*/Extracellular Vesicles*/metabolism

  • Source: Scientific reports [Sci Rep] 2024 Sep 09; Vol. 14 (1), pp. 20932. Date of Electronic Publication: 2024 Sep 09.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Inhibition of FBP1 expression by KMT5A through TWIST1 methylation is one of the mechanisms leading to chemoresistance in breast cancer.

  • Authors : Peng X; Department of Breast Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200233, P.R. China.; Ma L

Subjects: Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/genetics ; Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/drug therapy ; Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/pathology

  • Source: Oncology reports [Oncol Rep] 2024 Aug; Vol. 52 (2). Date of Electronic Publication: 2024 Jul 04.Publisher: D.A. Spandidos Country of Publication: Greece NLM ID: 9422756 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Metabolomics Reveals the Impact of Overexpression of Cytosolic Fructose-1,6-Bisphosphatase on Photosynthesis and Growth in Nannochloropsis gaditana .

  • Authors : Zhang Z; State Key Laboratory of Marine Environmental Science, Xiamen University, Xiamen 361000, China.; College of Ocean and Earth Sciences, Xiamen University, Xiamen 361000, China.

Subjects: Photosynthesis* ; Fructose-Bisphosphatase*/Fructose-Bisphosphatase*/Fructose-Bisphosphatase*/metabolism ; Fructose-Bisphosphatase*/Fructose-Bisphosphatase*/Fructose-Bisphosphatase*/genetics

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jun 20; Vol. 25 (12). Date of Electronic Publication: 2024 Jun 20.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

FBP1 orchestrates keratinocyte proliferation/differentiation and suppresses psoriasis through metabolic control of histone acetylation.

  • Authors : Zhang P; Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing, 100850, China.; Yang J

Subjects: Cell Differentiation* ; Cell Proliferation* ; Fructose-Bisphosphatase*/Fructose-Bisphosphatase*/Fructose-Bisphosphatase*/metabolism

  • Source: Cell death & disease [Cell Death Dis] 2024 Jun 04; Vol. 15 (6), pp. 392. Date of Electronic Publication: 2024 Jun 04.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  6,353 results for ""Fructose-Bisphosphatase""