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Academic Journal

Inhibition of RAN attenuates influenza a virus replication and nucleoprotein nuclear export.

  • Authors : Cao L; State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, People's Republic of China.; College of Animal Medicine, Huazhong Agricultural University, Wuhan, People's Republic of China.

Subjects: Virus Replication*/Virus Replication*/Virus Replication*/drug effects ; ran GTP-Binding Protein*/ran GTP-Binding Protein*/ran GTP-Binding Protein*/metabolism ; ran GTP-Binding Protein*/ran GTP-Binding Protein*/ran GTP-Binding Protein*/genetics

  • Source: Emerging microbes & infections [Emerg Microbes Infect] 2024 Dec; Vol. 13 (1), pp. 2387910. Date of Electronic Publication: 2024 Aug 12.Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101594885 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Discovery of SZJK-0421: A Novel Potent, Low Toxicity, Selective Second Generation of CRM1 Inhibitor for the Treatment of Both Hematological and Solid Tumors.

  • Authors : Miao H; College of Life Science, Nanjing Normal University, No. 1 Wenyuan Road, Nanjing 210037, P. R. China.; Qin Y

Subjects: Exportin 1 Protein* ; Karyopherins*/Karyopherins*/Karyopherins*/antagonists & inhibitors ; Karyopherins*/Karyopherins*/Karyopherins*/metabolism

  • Source: Journal of medicinal chemistry [J Med Chem] 2024 Nov 28; Vol. 67 (22), pp. 20595-20618. Date of Electronic Publication: 2024 Nov 07.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Selinexor targeting XPO1 promotes PEG3 nuclear accumulation and suppresses cholangiocarcinoma progression.

  • Authors : Xiang D; Department of General Surgery, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, No. 1 Minde Road, Nanchang, Jiangxi Province, 330006, China.; Department of General Surgery, The Affiliated Children's Hospital of Nanchang Medical College, Nangchang, 330000, China.

Subjects: Cholangiocarcinoma*/Cholangiocarcinoma*/Cholangiocarcinoma*/drug therapy ; Cholangiocarcinoma*/Cholangiocarcinoma*/Cholangiocarcinoma*/pathology ; Cholangiocarcinoma*/Cholangiocarcinoma*/Cholangiocarcinoma*/metabolism

  • Source: Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 2024 Nov; Vol. 94 (5), pp. 669-683. Date of Electronic Publication: 2024 Aug 05.Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7806519 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Discovery of Potent Covalent CRM1 Inhibitors Via a Customized Structure-Based Virtual Screening Pipeline and Bioassays.

  • Authors : Liu H; MOE Key Laboratory of Bio-Intelligent Manufacturing, School of Bioengineering, Dalian University of Technology, Dalian, Liaoning 116023, China.; Shen C

Subjects: Exportin 1 Protein* ; Karyopherins*/Karyopherins*/Karyopherins*/antagonists & inhibitors ; Karyopherins*/Karyopherins*/Karyopherins*/metabolism

  • Source: Journal of chemical information and modeling [J Chem Inf Model] 2024 Oct 14; Vol. 64 (19), pp. 7422-7431. Date of Electronic Publication: 2024 Oct 03.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101230060 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

HMGB2-induced calreticulin translocation required for immunogenic cell death and ferroptosis of cancer cells are controlled by the nuclear exporter XPO1.

  • Authors : Fan J; Penn/CHOP Center of Excellence in Friedreich's Ataxia, Center of Excellence in Environmental Toxicology, and Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Gillespie KP

Subjects: Calreticulin*/Calreticulin*/Calreticulin*/metabolism ; Calreticulin*/Calreticulin*/Calreticulin*/genetics ; Exportin 1 Protein*

  • Source: Communications biology [Commun Biol] 2024 Oct 01; Vol. 7 (1), pp. 1234. Date of Electronic Publication: 2024 Oct 01.Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Targeting the chromatin binding of exportin-1 disrupts NFAT and T cell activation.

  • Authors : Chen YF; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA.; Chemical Biology Program, Case Western Reserve University School of Medicine, Cleveland, OH, USA.

Subjects: Exportin 1 Protein* ; Receptors, Cytoplasmic and Nuclear*/Receptors, Cytoplasmic and Nuclear*/Receptors, Cytoplasmic and Nuclear*/metabolism ; Karyopherins*/Karyopherins*/Karyopherins*/metabolism

  • Source: Nature chemical biology [Nat Chem Biol] 2024 Oct; Vol. 20 (10), pp. 1260-1271. Date of Electronic Publication: 2024 Mar 25.Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The nuclear export protein XPO1 provides a peptide ligand for natural killer cells.

  • Authors : Blunt MD; School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.; Fisher H

Subjects: Exportin 1 Protein*/Exportin 1 Protein*/Exportin 1 Protein*/genetics ; Exportin 1 Protein*/Exportin 1 Protein*/Exportin 1 Protein*/metabolism ; Karyopherins*/Karyopherins*/Karyopherins*/metabolism

  • Source: Science advances [Sci Adv] 2024 Aug 23; Vol. 10 (34), pp. eado6566. Date of Electronic Publication: 2024 Aug 23.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic

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Academic Journal

Altered RNA export by SF3B1 mutants confers sensitivity to nuclear export inhibition.

  • Authors : Chaudhry S; Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, Miami, FL, USA.; Beckedorff F

Subjects: RNA Splicing Factors*/RNA Splicing Factors*/RNA Splicing Factors*/genetics ; RNA Splicing Factors*/RNA Splicing Factors*/RNA Splicing Factors*/metabolism ; Exportin 1 Protein*

  • Source: Leukemia [Leukemia] 2024 Sep; Vol. 38 (9), pp. 1894-1905. Date of Electronic Publication: 2024 Jul 13.Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Pantothenate-encapsulated liposomes combined with exercise for effective inhibition of CRM1-mediated PKM2 translocation in Alzheimer's therapy.

  • Authors : Chen Y; Department of Sports Medicine, Huashan Hospital, Fudan University, Shanghai, China; Department of Medical Sciences, Ningde Normal University College of Medical Sciences, No. 1 Xueyuan Road, Jiaocheng District, Ningde City, Fujian, China.

Subjects: Liposomes* ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/therapy ; Exportin 1 Protein*

  • Source: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2024 Sep; Vol. 373, pp. 336-357. Date of Electronic Publication: 2024 Jul 24.Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8607908 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

CDK4/6 inhibition augments anti-tumor efficacy of XPO1 inhibitor selinexor in natural killer/T-cell lymphoma.

  • Authors : Wang Y; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China; Department of Oncology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong Province, 510080, China.

Subjects: Cyclin-Dependent Kinase 4*/Cyclin-Dependent Kinase 4*/Cyclin-Dependent Kinase 4*/antagonists & inhibitors ; Cyclin-Dependent Kinase 6*/Cyclin-Dependent Kinase 6*/Cyclin-Dependent Kinase 6*/antagonists & inhibitors ; Exportin 1 Protein*/Exportin 1 Protein*/Exportin 1 Protein*/antagonists & inhibitors

  • Source: Cancer letters [Cancer Lett] 2024 Aug 10; Vol. 597, pp. 217080. Date of Electronic Publication: 2024 Jun 20.Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  1,287 results for ""Exportin 1 Protein""