Search Results

Insights from an academic endeavor into central nervous system drug discovery.

• Authors : van Veggel L; BIOMED Biomedical Research Institute, Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium (van Veggel L, Voets AM, Vanmierlo T).; Department of Psychiatry and Neuropsychology, Division of Translational Neuroscience, European Graduate School of Neuroscience, School for Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands (van Veggel L, Vanmierlo T).

• Source: Neural regeneration research [Neural Regen Res] 2025 Jun 01; Vol. 20 (6), pp. 1717-1718. Date of Electronic Publication: 2024 Jun 26.Publisher: Wolters Kluwer Health, Medknow Country of Publication: India NLM ID: 101316351 Publication Model: Print-Electronic Cited Medium: Print

Record details

Astrocytic Gap Junctions protein Cx43/Cx30 modulate EAAT1 and glutamate to mediate cerebral ischemia–reperfusion injury.

• Authors : Li, Min¹ (AUTHOR); Nie, Hongxia^1,2 (AUTHOR); He, Qianqian² (AUTHOR)

Subjects: *GTPASE-activating protein; *GLUTAMATE transporters; *NERVOUS system injuries

• Source: Brain Research. Jan2025, Vol. 1847, pN.PAG-N.PAG. 1p.

Record details

ZC3H13 may participate in the ferroptosis process of sepsis-induced cardiomyopathy by regulating the expression of Pnn and Rbm25.

• Authors : Lin, Wenji¹ (AUTHOR) ; Li, Haihong¹ (AUTHOR); Chang, Jing¹ (AUTHOR)

Subjects: *REVERSE transcriptase polymerase chain reaction; *GENE expression; *REACTIVE oxygen species

• Source: Gene. Jan2025, Vol. 933, pN.PAG-N.PAG. 1p.

Record details

Uncovering metabolic signatures in cancer-derived exosomes: LC-MS/MS and NMR profiling.

• Authors : Bajaj, Nandini; Sharma, Deepika

• Source: Nanoscale; 1/7/2024, Vol. 17 Issue 1, p287-303, 17p

Record details

Pharmacological activation of aldehyde dehydrogenase 2 inhibits ferroptosis via SLC7A11/GPX4 axis to reduce kidney stone formation.

• Authors : Zhang, Jingdong¹ (AUTHOR); Wang, Rui¹ (AUTHOR); Xie, Linguo¹ (AUTHOR)

Subjects: *ALDEHYDE dehydrogenase; *KIDNEY stones; *CALCIUM oxalate

• Source: European Journal of Pharmacology. Jan2025, Vol. 986, pN.PAG-N.PAG. 1p.

Record details

Electroconvulsive therapy combined with esketamine improved depression through PI3K/AKT/GLT-1 pathway.

• Authors : Zang X; Department of Anesthesiology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510630, PR China.; Zhang J

Subjects: Electroconvulsive Therapy* ; Ketamine*/Ketamine*/Ketamine*/pharmacology ; Ketamine*/Ketamine*/Ketamine*/administration & dosage

• Source: Journal of affective disorders [J Affect Disord] 2025 Jan 01; Vol. 368, pp. 282-294. Date of Electronic Publication: 2024 Sep 10.Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7906073 Publication Model: Print-Electronic Cited Medium:

Record details

Misprogramming of glucose metabolism impairs recovery of hippocampal slices from neuronal GLT-1 knockout mice and contributes to excitotoxic injury through mitochondrial superoxide production.

• Authors : Li S; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Wang J

Subjects: Glucose*/Glucose*/Glucose*/metabolism ; Glucose*/Glucose*/Glucose*/deficiency ; Hippocampus*/Hippocampus*/Hippocampus*/metabolism

• Source: Journal of neurochemistry [J Neurochem] 2025 Jan; Vol. 169 (1), pp. e16205. Date of Electronic Publication: 2024 Aug 28.Publisher: Wiley on behalf of the International Society for Neurochemistry Country of Publication: England NLM ID: 2985190R Publication Model: Print-Electronic

Record details

Increased forebrain EAAT3 expression confers resilience to chronic stress.

• Authors : Ardiles NM; Programa de Doctorado en Ciencias, Mención Neurociencia, Universidad de Valparaíso, Valparaíso, Chile.; Centro Interdisciplinario de Neurociencia de Valparaíso (CINV), Universidad de Valparaíso, Valparaíso, Chile.

Subjects: Stress, Psychological*/Stress, Psychological*/Stress, Psychological*/metabolism ; Stress, Psychological*/Stress, Psychological*/Stress, Psychological*/psychology ; Prosencephalon*/Prosencephalon*/Prosencephalon*/metabolism

• Source: Journal of neurochemistry [J Neurochem] 2025 Jan; Vol. 169 (1), pp. e16216. Date of Electronic Publication: 2024 Sep 08.Publisher: Wiley on behalf of the International Society for Neurochemistry Country of Publication: England NLM ID: 2985190R Publication Model: Print-Electronic

Record details

The kinase LRRK2 is required for the physiological function and expression of the glial glutamate transporter EAAT2 (SLC1A2).

• Authors : Di Iacovo A; Department of Biotechnology and Life Sciences, Laboratory of Cellular and Molecular Physiology, University of Insubria, Varese, Italy.; Centre for Neuroscience, University of Insubria, Varese, Italy.

Subjects: Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/genetics ; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/metabolism ; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/biosynthesis

• Source: Journal of neurochemistry [J Neurochem] 2025 Jan; Vol. 169 (1), pp. e16265.Publisher: Wiley on behalf of the International Society for Neurochemistry Country of Publication: England NLM ID: 2985190R Publication Model: Print Cited

Record details

Astroglial membrane camouflaged Ptbp1 siRNA delivery hinders glutamate homeostasis via SDH/Nrf2 pathway.

• Authors : Liu, Yan^1,2 (AUTHOR); Ren, Jian^1,3,4 (AUTHOR); Zhang, Wenlong^1,5,6 (AUTHOR)

Subjects: *ALTERNATIVE RNA splicing; *GLUTAMATE transporters; *SUCCINATE dehydrogenase

• Source: Biomaterials. Jan2025, Vol. 312, pN.PAG-N.PAG. 1p.

Record details