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Academic Journal

Structure of epoxide hydrolase 2 from Mangifera indica throws light on the substrate specificity determinants of plant epoxide hydrolases.

  • Authors : Bhoite A; Division of Biochemical Sciences, CSIR-National Chemical Laboratory, Dr. Homi Bhabha Road, Pune- 411008, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad- 201002, India.

Subjects: Epoxide Hydrolases*/Epoxide Hydrolases*/Epoxide Hydrolases*/metabolism ; Epoxide Hydrolases*/Epoxide Hydrolases*/Epoxide Hydrolases*/chemistry ; Epoxide Hydrolases*/Epoxide Hydrolases*/Epoxide Hydrolases*/genetics

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2024 Nov 12; Vol. 733, pp. 150444. Date of Electronic Publication: 2024 Jul 24.Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

High-throughput selection of (new) enzymes: phage display-mediated isolation of alkyl halide hydrolases from a library of active-site mutated epoxide hydrolases.

  • Authors : Blazic M; Department of Chemistry - BMC, Uppsala University, Box 576, SE-751 23 Uppsala, Sweden. .; Gautier C

Subjects: Epoxide Hydrolases*/Epoxide Hydrolases*/Epoxide Hydrolases*/metabolism ; Epoxide Hydrolases*/Epoxide Hydrolases*/Epoxide Hydrolases*/chemistry ; Epoxide Hydrolases*/Epoxide Hydrolases*/Epoxide Hydrolases*/genetics

  • Source: Faraday discussions [Faraday Discuss] 2024 Sep 11; Vol. 252 (0), pp. 115-126. Date of Electronic Publication: 2024 Sep 11.Publisher: Faraday Division, Royal Society of Chemistry Country of Publication: England NLM ID: 9212301 Publication Model: Electronic Cited Medium:

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Academic Journal

Structural insights into the distinct substrate preferences of two bacterial epoxide hydrolases.

  • Authors : Hwang J; Division of Life Sciences, Korea Polar Research Institute, Incheon 21990, Republic of Korea; Department of Polar Sciences, University of Science and Technology, Incheon 21990, Republic of Korea.

Subjects: Epoxide Hydrolases*/Epoxide Hydrolases*/Epoxide Hydrolases*/chemistry ; Bacteria*/Bacteria*/Bacteria*/metabolism; Binding Sites

  • Source: International journal of biological macromolecules [Int J Biol Macromol] 2024 Apr; Vol. 264 (Pt 1), pp. 130419. Date of Electronic Publication: 2024 Feb 27.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Multiomics-guided mining and characterization of epoxide hydrolase involved in camptothecin biosynthesis from Camptotheca acuminata.

  • Authors : Pu X; College of Science, Sichuan Agricultural University, Ya'an 625104, China; State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Beijing 100700, China

Subjects: Epoxide Hydrolases*/Epoxide Hydrolases*/Epoxide Hydrolases*/metabolism ; Epoxide Hydrolases*/Epoxide Hydrolases*/Epoxide Hydrolases*/genetics ; Camptothecin*/Camptothecin*/Camptothecin*/biosynthesis

  • Source: Bioorganic chemistry [Bioorg Chem] 2024 Dec; Vol. 153, pp. 107980. Date of Electronic Publication: 2024 Nov 19.Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Improving Hydrolytic Activity and Enantioselectivity of Epoxide Hydrolase from Phanerochaete chrysosporium by Directed Evolution.

  • Authors : Shao H; College of Life Sciences, Sichuan Normal University, Chenglong Avenue, Chengdu 610101, China.; Xu P

Subjects: Epoxide Hydrolases*/Epoxide Hydrolases*/Epoxide Hydrolases*/metabolism ; Epoxide Hydrolases*/Epoxide Hydrolases*/Epoxide Hydrolases*/genetics ; Epoxide Hydrolases*/Epoxide Hydrolases*/Epoxide Hydrolases*/chemistry

  • Source: Molecules (Basel, Switzerland) [Molecules] 2024 Oct 14; Vol. 29 (20). Date of Electronic Publication: 2024 Oct 14.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Discovery of glycosidated glycyrrhetinic acid derivatives: Natural product-based soluble epoxide hydrolase inhibitors.

  • Authors : Liu Q; Key Laboratory of Medicinal Molecule Science and Pharmaceutical Engineering, School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, 102488, China.; Wang YX

Subjects: Epoxide Hydrolases*/Epoxide Hydrolases*/Epoxide Hydrolases*/antagonists & inhibitors ; Epoxide Hydrolases*/Epoxide Hydrolases*/Epoxide Hydrolases*/metabolism ; Enzyme Inhibitors*/Enzyme Inhibitors*/Enzyme Inhibitors*/pharmacology

  • Source: European journal of medicinal chemistry [Eur J Med Chem] 2024 Dec 15; Vol. 280, pp. 116937. Date of Electronic Publication: 2024 Oct 09.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Rational mutagenesis of an epoxide hydrolase and its structural mechanism for the enantioselectivity improvement toward chiral ortho-fluorostyrene oxide.

  • Authors : Lu ZY; School of Pharmacy & School of Biological and Food Engineering, Changzhou University, Changzhou 213164, PR China.; Liao X

Subjects: Epoxide Hydrolases*/Epoxide Hydrolases*/Epoxide Hydrolases*/genetics ; Epoxide Hydrolases*/Epoxide Hydrolases*/Epoxide Hydrolases*/chemistry ; Epoxide Hydrolases*/Epoxide Hydrolases*/Epoxide Hydrolases*/metabolism

  • Source: International journal of biological macromolecules [Int J Biol Macromol] 2024 Dec; Vol. 282 (Pt 3), pp. 136864. Date of Electronic Publication: 2024 Oct 29.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Metabolomics reveals soluble epoxide hydrolase as a therapeutic target for high-sucrose diet-mediated gut barrier dysfunction.

  • Authors : Lin AZ; Department of Anesthesia of the Second Affiliated Hospital and CNTTI of College of Pharmacy, Chongqing Medical University, Chongqing 400016, China.; Basic Medicine Research and Innovation Center for Novel Target and Therapeutic Intervention, Ministry of Education, Chongqing 400016, China.

Subjects: Epoxide Hydrolases*/Epoxide Hydrolases*/Epoxide Hydrolases*/metabolism ; Epoxide Hydrolases*/Epoxide Hydrolases*/Epoxide Hydrolases*/antagonists & inhibitors ; Epoxide Hydrolases*/Epoxide Hydrolases*/Epoxide Hydrolases*/genetics

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Nov 26; Vol. 121 (48), pp. e2409841121. Date of Electronic Publication: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Inhibition of soluble epoxide hydrolase reverses bone loss in periodontitis by upregulating EMCN and inhibiting osteoclasts.

  • Authors : Li J; School of Stomatology, Dalian Medical University, Dalian, 116044, China.; The Affiliated Stomatological Hospital of Dalian Medical University School of Stomatology, Dalian, 116044, China.

Subjects: Epoxide Hydrolases*/Epoxide Hydrolases*/Epoxide Hydrolases*/metabolism ; Epoxide Hydrolases*/Epoxide Hydrolases*/Epoxide Hydrolases*/antagonists & inhibitors ; Epoxide Hydrolases*/Epoxide Hydrolases*/Epoxide Hydrolases*/genetics

  • Source: Stem cell research & therapy [Stem Cell Res Ther] 2024 Nov 25; Vol. 15 (1), pp. 451. Date of Electronic Publication: 2024 Nov 25.Publisher: BioMed Central Country of Publication: England NLM ID: 101527581 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-6512

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Academic Journal

Restoration of ARA metabolic disorders in vascular smooth muscle cells alleviates intimal hyperplasia.

  • Authors : Wu H; Department of Laboratory Medicine, The Third Xiangya Hospital, Central South University, Changsha, 410013, China.; Li D

Subjects: Muscle, Smooth, Vascular*/Muscle, Smooth, Vascular*/Muscle, Smooth, Vascular*/drug effects ; Muscle, Smooth, Vascular*/Muscle, Smooth, Vascular*/Muscle, Smooth, Vascular*/pathology ; Muscle, Smooth, Vascular*/Muscle, Smooth, Vascular*/Muscle, Smooth, Vascular*/metabolism

  • Source: European journal of pharmacology [Eur J Pharmacol] 2024 Nov 15; Vol. 983, pp. 176824. Date of Electronic Publication: 2024 Sep 10.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  11,690 results for ""Epoxide Hydrolases""