Search Results

Bright line or lottery? On significance and value in medical decision making.

• Authors : Mahlich J; Miltenyi Biomedicine, Bergisch Gladbach, Germany & Dice - University of Düsseldorf, Düsseldorf, Germany.; Dheban S

• Source: Journal of market access & health policy [J Mark Access Health Policy] 2021 Sep 20; Vol. 9 (1), pp. 1981574. Date of Electronic Publication: 2021 Sep 20 (Print Publication: Publisher: MDPI Country of Publication: United States NLM ID: 101670174 Publication Model: eCollection Cited Medium: Print ISSN: 2001-6689

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Can adaptive clinical trials help to solve the productivity crisis of the pharmaceutical industry? - a scenario analysis.

• Authors : Mahlich J; Health Economics and Outcomes Research, Janssen, Pharmaceutical Companies of Johnson & Johnson, Neuss, Germany. .; Düsseldorf Institute of Competition Economics (DICE), University of Düsseldorf, Düsseldorf, Germany. .

• Source: Health economics review [Health Econ Rev] 2021 Jan 16; Vol. 11 (1), pp. 4. Date of Electronic Publication: 2021 Jan 16.Publisher: BioMed Central Country of Publication: Germany NLM ID: 101583209 Publication Model: Electronic Cited Medium: Print ISSN: 2191-1991

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Detection of Independent Associations of Plasma Lipidomic Parameters with Insulin Sensitivity Indices Using Data Mining Methodology.

• Authors : Kopprasch S; Department of Internal Medicine 3, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.; Dheban S

Subjects: Data Mining/Data Mining/Data Mining/*methods ; Diabetes Mellitus, Type 2/Diabetes Mellitus, Type 2/Diabetes Mellitus, Type 2/*metabolism ; Glucose Intolerance/Glucose Intolerance/Glucose Intolerance/*metabolism

• Source: PloS one [PLoS One] 2016 Oct 13; Vol. 11 (10), pp. e0164173. Date of Electronic Publication: 2016 Oct 13 (Print Publication: 2016).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Comparison of the Latin America Regulation Landscape and International Reference Health Authorities to Hasten Drug Registration and Clinical Research Applications.

• Authors : Argotti, Urimara; Leyens, Lada; Lisbona, Carlos

• Source: Therapeutic Innovation & Regulatory Science; Nov2023, Vol. 57 Issue 6, p1287-1297, 11p

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A systematic review of randomised controlled trials with adaptive and traditional group sequential designs – applications in cardiovascular clinical trials.

• Authors : Zhang, Jufen; Saju, Christy

Subjects: RANDOMIZED controlled trials; CLINICAL trials; TRIAL practice

• Source: BMC Medical Research Methodology; 9/7/2023, Vol. 23 Issue 1, p1-9, 9p

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Improving resource utilisation in SLE drug development through innovative trial design.

• Authors : Garces, Sandra; Karis, Elaine; Merrill, Joan T.

• Source: Lupus Science & Medicine; 2023, Vol. 10 Issue 2, p1-8, 8p

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Change in fatty acid composition of plasma triglyceride caused by a 2 week comprehensive risk management for diabetes: A prospective observational study of type 2 diabetes patients with supercritical fluid chromatography/mass spectrometry‐based semi‐target lipidomic analysis

• Authors : Taya, Naohiro; Katakami, Naoto; Omori, Kazuo

Subjects: SUPERCRITICAL fluid chromatography; TYPE 2 diabetes; FATTY acids

• Source: Journal of Diabetes Investigation; Jan2023, Vol. 14 Issue 1, p102-110, 9p

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Metabolic signatures of insulin resistance in non-diabetic individuals.

• Authors : Arjmand, Babak; Ebrahimi Fana, Saeed; Ghasemi, Erfan

Subjects: INSULIN resistance risk factors; HOMEOSTASIS; GLYCOSYLATED hemoglobinIRAN

• Source: BMC Endocrine Disorders; 8/24/2022, Vol. 22 Issue 1, p1-11, 11p

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Practical guidance for planning resources required to support publicly-funded adaptive clinical trials.

• Authors : Wason, James M. S.; Dimairo, Munyaradzi; Biggs, Katie

• Source: BMC Medicine; 8/9/2022, Vol. 20 Issue 1, p1-12, 12p

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Longitudinal Plasma Lipidome and Risk of Type 2 Diabetes in a Large Sample of American Indians With Normal Fasting Glucose: The Strong Heart Family Study.

• Authors : Miao, Guanhong; Zhang, Ying; Huo, Zhiguang

Subjects: TYPE 2 diabetes; LIQUID chromatography-mass spectrometry; BLOOD lipids

• Source: Diabetes Care; Dec2021, Vol. 44 Issue 12, p2664-2672, 9p

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