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Academic Journal

Systemic Clodronate Liposome Treatment for Depletion of Blood-Contacting Phagocytes and Investigation of Their Role in the Control of Bunyavirus Viremia.

  • Authors : Ander SE; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO, USA.; Davenport BJ

Subjects: Liposomes* ; Clodronic Acid*/Clodronic Acid*/Clodronic Acid*/pharmacology ; Clodronic Acid*/Clodronic Acid*/Clodronic Acid*/administration & dosage

  • Source: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2025; Vol. 2893, pp. 285-298.Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029

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Academic Journal

Depletion of macrophages and osteoclast precursors mitigates iron overload-mediated bone loss.

  • Authors : Passin V; Department of Medicine III & Center for Healthy Aging, Medical Faculty and University Hospital Carl Gustav Carus, Dresden University of Technology, Dresden, Germany.; Ledesma-Colunga MG

Subjects: Iron Overload*/Iron Overload*/Iron Overload*/pathology ; Iron Overload*/Iron Overload*/Iron Overload*/metabolism ; Osteoclasts*/Osteoclasts*/Osteoclasts*/metabolism

  • Source: IUBMB life [IUBMB Life] 2025 Jan; Vol. 77 (1), pp. e2928. Date of Electronic Publication: 2024 Nov 18.Publisher: Published for the International Union of Biochemistry and Molecular Biology by Taylor & Francis Country of Publication: England NLM ID: 100888706

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Academic Journal

Macrophage Inhibitor Clodronate Enhances Liver Transduction of Lentiviral but Not Adeno-Associated Viral Vectors or mRNA Lipid Nanoparticles in Neonatal and Juvenile Mice.

  • Authors : Touramanidou L; Great Ormond Street Institute of Child Health, University College London, London WC1E 1EH, UK.; Gurung S

Subjects: Dependovirus*/Dependovirus*/Dependovirus*/genetics ; Genetic Vectors* ; Nanoparticles*/Nanoparticles*/Nanoparticles*/chemistry

  • Source: Cells [Cells] 2024 Nov 29; Vol. 13 (23). Date of Electronic Publication: 2024 Nov 29.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

Validity evaluation of a rat model of monoiodoacetate-induced osteoarthritis with clinically effective drugs.

  • Authors : Sasaki Y; Central Research Laboratory, Research & Development Division, Seikagaku Corporation, Tateno 3-1253, Higashiyamato-shi, Tokyo, 207-0021, Japan. .; Kijima K

Subjects: Iodoacetic Acid* ; Diclofenac*/Diclofenac*/Diclofenac*/pharmacology ; Anti-Inflammatory Agents, Non-Steroidal*/Anti-Inflammatory Agents, Non-Steroidal*/Anti-Inflammatory Agents, Non-Steroidal*/pharmacology

  • Source: BMC musculoskeletal disorders [BMC Musculoskelet Disord] 2024 Nov 29; Vol. 25 (1), pp. 975. Date of Electronic Publication: 2024 Nov 29.Publisher: BioMed Central Country of Publication: England NLM ID: 100968565 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2474

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Academic Journal

Both TREM2-dependent macrophages and Kupffer cells play a protective role in APAP-induced acute liver injury.

  • Authors : Chao S; Department of Toxicology and Nutrition, School of Public Health, Cheeloo College of Medicine, Shandong University, 44 West Wenhua Road, Jinan, Shandong 250012, China; Qinghai Center for Disease Control and Prevention, No. 55, Bayi Middle Road, Chengdong District, Xining City, Qinghai Province 810000, China.

Subjects: Kupffer Cells*/Kupffer Cells*/Kupffer Cells*/metabolism ; Kupffer Cells*/Kupffer Cells*/Kupffer Cells*/immunology ; Acetaminophen*

  • Source: International immunopharmacology [Int Immunopharmacol] 2024 Nov 15; Vol. 141, pp. 112926. Date of Electronic Publication: 2024 Aug 18.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Macrophage-depleted young mice are beneficial in vivo models to assess the translocation of Klebsiella pneumonia from the gastrointestinal tract to the liver in the elderly.

  • Authors : Tsugawa H; Transkingdom Signaling Research Unit, Division of Host Defense Mechanism, Tokai University School of Medicine, Isehara, 259-1193, Japan. Electronic address: .; Tsubaki S

Subjects: Klebsiella pneumoniae* ; Liver*/Liver*/Liver*/microbiology ; Liver*/Liver*/Liver*/pathology

  • Source: Microbes and infection [Microbes Infect] 2024 Nov-Dec; Vol. 26 (8), pp. 105371. Date of Electronic Publication: 2024 Jun 05.Publisher: Elsevier Country of Publication: France NLM ID: 100883508 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1769-714X

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Academic Journal

Delayed macrophage targeting by clodronate liposomes worsens the progression of cytokine storm syndrome.

  • Authors : Khanna K; Department of Orthopedics, Washington University in St Louis, St Louis, MO, United States.; Eul E

Subjects: Clodronic Acid*/Clodronic Acid*/Clodronic Acid*/administration & dosage ; Clodronic Acid*/Clodronic Acid*/Clodronic Acid*/pharmacology ; Macrophages*/Macrophages*/Macrophages*/immunology

  • Source: Frontiers in immunology [Front Immunol] 2024 Oct 28; Vol. 15, pp. 1477449. Date of Electronic Publication: 2024 Oct 28 (Print Publication: 2024).Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Clodronate Reduces ATP-Containing Microvesicle Releasing Induced by Nociceptive Stimuli in Human Keratinocytes.

  • Authors : Renò F; Department of Health Sciences, University of Milan, Via A. di Rudini 8, 20142 Milan, Italy.; De Andrea M

Subjects: Keratinocytes*/Keratinocytes*/Keratinocytes*/drug effects ; Keratinocytes*/Keratinocytes*/Keratinocytes*/metabolism ; Adenosine Triphosphate*/Adenosine Triphosphate*/Adenosine Triphosphate*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Aug 02; Vol. 25 (15). Date of Electronic Publication: 2024 Aug 02.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

In vivo upstream factors of mouse hepatotoxic mechanism with sustained hepatic glutathione depletion: Acetaminophen metabolite-erythrocyte adducts and splenic macrophage-generated reactive oxygen species.

  • Authors : Tanino T; Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Bouji Nishihama, Yamashiro-cho, Tokushima, 770-8514, Japan. Electronic address: .; Ueda Y

Subjects: Acetaminophen*/Acetaminophen*/Acetaminophen*/toxicity ; Reactive Oxygen Species*/Reactive Oxygen Species*/Reactive Oxygen Species*/metabolism ; Glutathione*/Glutathione*/Glutathione*/metabolism

  • Source: Chemico-biological interactions [Chem Biol Interact] 2024 Aug 01; Vol. 398, pp. 111091. Date of Electronic Publication: 2024 May 31.Publisher: Elsevier Country of Publication: Ireland NLM ID: 0227276 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7786

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Academic Journal

Lipopolysaccharide modification enhances the inhibitory effect of clodronate liposomes on hepatic fibrosis by depletion of macrophages and hepatic stellate cells.

  • Authors : Zhang L; School of Pharmacy, Anhui Medical University, Hefei, China; Department of Clinical Pharmacology, The Second Hospital of Anhui Medical University, Hefei, China

Subjects: Hepatic Stellate Cells*/Hepatic Stellate Cells*/Hepatic Stellate Cells*/drug effects ; Hepatic Stellate Cells*/Hepatic Stellate Cells*/Hepatic Stellate Cells*/metabolism ; Liposomes*/Liposomes*/Liposomes*/chemistry

  • Source: Chemico-biological interactions [Chem Biol Interact] 2024 May 25; Vol. 395, pp. 111015. Date of Electronic Publication: 2024 Apr 23.Publisher: Elsevier Country of Publication: Ireland NLM ID: 0227276 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7786

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  • 1-10 of  778 results for ""Clodronic Acid pharmacology""