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Academic Journal

Farnesoid X Receptor: Effective alleviation of rifampicin -induced liver injury.

  • Authors : Zhou Y; Key Laboratory of Receptors-Mediated Gene Regulation, School of Basic Medical Sciences, Henan University, Henan, PR China; Hebi Key Laboratory of Liver Disease, Hebi Key Laboratory of Cardiovascular Diseases, Hebi Key Laboratory of Energy Metabolism, People's Hospital of Hebi, Henan University, Henan, PR China.

Subjects: Rifampin*/Rifampin*/Rifampin*/adverse effects ; Receptors, Cytoplasmic and Nuclear*/Receptors, Cytoplasmic and Nuclear*/Receptors, Cytoplasmic and Nuclear*/metabolism ; Receptors, Cytoplasmic and Nuclear*/Receptors, Cytoplasmic and Nuclear*/Receptors, Cytoplasmic and Nuclear*/genetics

  • Source: International immunopharmacology [Int Immunopharmacol] 2024 Sep 30; Vol. 139, pp. 112799. Date of Electronic Publication: 2024 Jul 27.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Hepatoprotective effects of zingerone on sodium arsenite-induced hepatotoxicity in rats: Modulating the levels of caspase-3/Bax/Bcl-2, NLRP3/NF-κB/TNF-α and ATF6/IRE1/PERK/GRP78 signaling pathways.

  • Authors : Eriten B; Department of Pathology, Sancaktepe Sehit Prof. Dr. Ilhan Varank Training and Research Hospital, Istanbul, Turkey. Electronic address: .; Caglayan C

Subjects: Rats, Sprague-Dawley* ; Signal Transduction*/Signal Transduction*/Signal Transduction*/drug effects ; Chemical and Drug Induced Liver Injury*/Chemical and Drug Induced Liver Injury*/Chemical and Drug Induced Liver Injury*/metabolism

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2024 Sep 17; Vol. 725, pp. 150258. Date of Electronic Publication: 2024 Jun 11.Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Effects of compound Anoectochilus roxburghii (Wall.) Lindl. oral liquid on relative metabolic enzymes and various biochemical indices in Wistar rats with isoniazid-induced liver injury.

  • Authors : Lin R; School of Pharmacy, Fujian Medical University, Fuzhou, Fujian 350122, China.; Wu P

Subjects: Isoniazid*/Isoniazid*/Isoniazid*/toxicity ; Rats, Wistar* ; Chemical and Drug Induced Liver Injury*/Chemical and Drug Induced Liver Injury*/Chemical and Drug Induced Liver Injury*/prevention & control

  • Source: Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2024 Sep 15; Vol. 248, pp. 116249. Date of Electronic Publication: 2024 May 21.Publisher: Elsevier Science Country of Publication: England NLM ID: 8309336 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Protective effects and mechanism of Sangyu granule on acetaminophen-induced liver injury in mice.

  • Authors : Xiao K; Department of Pharmacy, Xijing Hospital, Air Force Medical University, Xi'an, 710032, Shaanxi Province, China; College of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, 712046, Shaanxi Province, China.

Subjects: Acetaminophen*/Acetaminophen*/Acetaminophen*/toxicity ; Chemical and Drug Induced Liver Injury*/Chemical and Drug Induced Liver Injury*/Chemical and Drug Induced Liver Injury*/prevention & control ; Chemical and Drug Induced Liver Injury*/Chemical and Drug Induced Liver Injury*/Chemical and Drug Induced Liver Injury*/drug therapy

  • Source: Journal of ethnopharmacology [J Ethnopharmacol] 2024 Sep 15; Vol. 331, pp. 118282. Date of Electronic Publication: 2024 May 01.Publisher: Elsevier Sequoia Country of Publication: Ireland NLM ID: 7903310 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Taraxasterol protects against acetaminophen-induced hepatotoxicity by reducing liver inflammatory response and ameliorating oxidative stress in mice.

  • Authors : Lin W; School of Pharmacy, Nantong University, Nantong 226019, China.; Gu B

Subjects: Acetaminophen* ; Oxidative Stress*/Oxidative Stress*/Oxidative Stress*/drug effects ; Chemical and Drug Induced Liver Injury*/Chemical and Drug Induced Liver Injury*/Chemical and Drug Induced Liver Injury*/drug therapy

  • Source: International immunopharmacology [Int Immunopharmacol] 2024 Sep 10; Vol. 138, pp. 112580. Date of Electronic Publication: 2024 Jun 28.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Chlordecone-induced hepatotoxicity and fibrosis are mediated by the proteasomal degradation of septins.

  • Authors : Léger T; ANSES, French Agency for Food, Environmental and Occupational Health & Safety, Toxicology of Contaminants Unit, Fougères Laboratory, 35306 Fougères CEDEX, France. Electronic address: .; Alilat S

Subjects: Proteasome Endopeptidase Complex*/Proteasome Endopeptidase Complex*/Proteasome Endopeptidase Complex*/metabolism ; Septins*/Septins*/Septins*/metabolism ; Hepatocytes*/Hepatocytes*/Hepatocytes*/drug effects

  • Source: Journal of hazardous materials [J Hazard Mater] 2024 Sep 05; Vol. 476, pp. 135177. Date of Electronic Publication: 2024 Jul 11.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9422688 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Insights gained into the injury mechanism of drug and herb induced liver injury in the hepatic microenvironment.

  • Authors : Zhang X; Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, China.; Geng Q

Subjects: Chemical and Drug Induced Liver Injury*/Chemical and Drug Induced Liver Injury*/Chemical and Drug Induced Liver Injury*/etiology ; Chemical and Drug Induced Liver Injury*/Chemical and Drug Induced Liver Injury*/Chemical and Drug Induced Liver Injury*/metabolism ; Chemical and Drug Induced Liver Injury*/Chemical and Drug Induced Liver Injury*/Chemical and Drug Induced Liver Injury*/pathology

  • Source: Toxicology [Toxicology] 2024 Sep; Vol. 507, pp. 153900. Date of Electronic Publication: 2024 Jul 29.Publisher: Elsevier Country of Publication: Ireland NLM ID: 0361055 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3185

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Academic Journal

Metabolism-dependent inhibition of CYP2E1 by isoniazid, a mediator of idiosyncratic liver injury.

  • Authors : Masubuchi Y; Laboratory of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Chiba Institute of Science, 15-8 Shiomi-cho, Choshi, Chiba, Japan. Electronic address: .; Miyauchi K

Subjects: Isoniazid*/Isoniazid*/Isoniazid*/metabolism ; Cytochrome P-450 CYP2E1*/Cytochrome P-450 CYP2E1*/Cytochrome P-450 CYP2E1*/metabolism ; Microsomes, Liver*/Microsomes, Liver*/Microsomes, Liver*/metabolism

  • Source: Chemico-biological interactions [Chem Biol Interact] 2024 Sep 01; Vol. 400, pp. 111160. Date of Electronic Publication: 2024 Jul 22.Publisher: Elsevier Country of Publication: Ireland NLM ID: 0227276 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7786

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Academic Journal

Should high-dose N-acetylcysteine be given in cases of massive paracetamol overdoses: A narrative review.

  • Authors : Erichsen PA; Department of Clinical Pharmacology, Copenhagen University Hospital, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.; Dalhoff K

Subjects: Acetylcysteine*/Acetylcysteine*/Acetylcysteine*/administration & dosage ; Acetylcysteine*/Acetylcysteine*/Acetylcysteine*/therapeutic use ; Acetaminophen*/Acetaminophen*/Acetaminophen*/poisoning

  • Source: Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2024 Sep; Vol. 135 (3), pp. 285-294. Date of Electronic Publication: 2024 Jul 14.Publisher: Blackwell Country of Publication: England NLM ID: 101208422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-7843

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Academic Journal

mtROS-mediated mitophagy is involved in aflatoxin-B 1 induced liver injury in ducks.

  • Authors : Cui Y; College of Animal Science and Technology, Inner Mongolia Minzu University, Tongliao 028000, China.; Wang Q

Subjects: Aflatoxin B1*/Aflatoxin B1*/Aflatoxin B1*/toxicity ; Ducks* ; Mitophagy*/Mitophagy*/Mitophagy*/drug effects

  • Source: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP [Comp Biochem Physiol C Toxicol Pharmacol] 2024 Sep; Vol. 283, pp. 109942. Date of Electronic Publication: Publisher: Elsevier Science Country of Publication: United States NLM ID: 100959500 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  35,525 results for ""Chemical and Drug Induced Liver Injury""