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Academic Journal

The first in-human study to evaluate the antiplatelet properties of the clopidogrel conjugate DT-678 in acute coronary syndrome patients and healthy volunteers.

  • Authors : Liu Z; Department of Cardiology, Peking University First Hospital, Beijing, China.; Liu S

Subjects: Acute Coronary Syndrome*/Acute Coronary Syndrome*/Acute Coronary Syndrome*/drug therapy ; Platelet Aggregation Inhibitors*/Platelet Aggregation Inhibitors*/Platelet Aggregation Inhibitors*/pharmacology ; Platelet Aggregation Inhibitors*/Platelet Aggregation Inhibitors*/Platelet Aggregation Inhibitors*/administration & dosage

  • Source: British journal of pharmacology [Br J Pharmacol] 2025 Jan; Vol. 182 (1), pp. 131-141. Date of Electronic Publication: 2024 Oct 04.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Academic Journal

Effect of SLC22A1 polymorphism on the pharmacokinetics of proguanil in Korean: A semi-physiologic population pharmacokinetic approach.

  • Authors : Khwarg J; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Korea.; Yang E

Subjects: Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/genetics ; Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/metabolism ; Octamer Transcription Factor-1*/Octamer Transcription Factor-1*/Octamer Transcription Factor-1*/genetics

  • Source: Clinical and translational science [Clin Transl Sci] 2024 Dec; Vol. 17 (12), pp. e70103.Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Computational journey to unveil organophosphorothioate pesticides' metabolism: A focus on chlorpyrifos and CYP2C19 mutational landscape.

  • Authors : Pedroni L; Department of Food and Drug, University of Parma, Parma, Italy.; Perugino F

Subjects: Chlorpyrifos*/Chlorpyrifos*/Chlorpyrifos*/toxicity ; Chlorpyrifos*/Chlorpyrifos*/Chlorpyrifos*/metabolism ; Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/genetics

  • Source: Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2024 Dec; Vol. 288, pp. 117354. Date of Electronic Publication: 2024 Nov 20.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7805381 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Improving CYP2C19 phenotyping using stereoselective omeprazole and 5-hydroxy-omeprazole metabolic ratios.

  • Authors : Abouir K; Division of Clinical Pharmacology and Toxicology, Geneva University Hospitals, Geneva, Switzerland.; School of Pharmaceutical Sciences

Subjects: Omeprazole*/Omeprazole*/Omeprazole*/pharmacokinetics ; Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/metabolism ; Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/genetics

  • Source: Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2024 Dec; Vol. 135 (6), pp. 755-766. Date of Electronic Publication: 2024 Oct 09.Publisher: Blackwell Country of Publication: England NLM ID: 101208422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-7843

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Academic Journal

Population pharmacokinetic analysis of zastaprazan (JP-1366), a novel potassium-competitive acid blocker, in patients and healthy volunteers.

  • Authors : Yang E; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Korea.; Hwang I

Subjects: Gastroesophageal Reflux*/Gastroesophageal Reflux*/Gastroesophageal Reflux*/drug therapy ; Healthy Volunteers* ; Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/metabolism

  • Source: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2024 Dec; Vol. 13 (12), pp. 2150-2158. Date of Electronic Publication: 2024 Sep 13.Publisher: Wiley Country of Publication: United States NLM ID: 101580011 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

A type of self-assembled and label-free DNA-modified electrochemical biosensors based on magnetic α-Fe 2 O 3 /Fe 3 O 4 heterogeneous nanorods for ultra-sensitive detection of CYP2C19*3.

  • Authors : Zhao S; School of Pharmacy, Jiangsu University, Zhenjiang 212013, PR China.; Deng P

Subjects: Biosensing Techniques*/Biosensing Techniques*/Biosensing Techniques*/methods ; Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/genetics ; Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/metabolism

  • Source: Bioelectrochemistry (Amsterdam, Netherlands) [Bioelectrochemistry] 2024 Dec; Vol. 160, pp. 108792. Date of Electronic Publication: 2024 Aug 06.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 100953583 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Deep mutational scanning of CYP2C19 in human cells reveals a substrate specificity-abundance tradeoff.

  • Authors : Boyle GE; Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA.; Sitko KA

Subjects: Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/genetics ; Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/metabolism ; Cytochrome P-450 CYP2C9*/Cytochrome P-450 CYP2C9*/Cytochrome P-450 CYP2C9*/genetics

  • Source: Genetics [Genetics] 2024 Nov 06; Vol. 228 (3).Publisher: Oxford University Press Country of Publication: United States NLM ID: 0374636 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Efficacy and safety of dual antiplatelet therapy in the elderly for stroke prevention: a subgroup analysis of the CHANCE-2 trial.

  • Authors : Zhang X; Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; China National Clinical Research Center for Neurological Diseases, Beijing, China.

Subjects: Platelet Aggregation Inhibitors*/Platelet Aggregation Inhibitors*/Platelet Aggregation Inhibitors*/adverse effects ; Platelet Aggregation Inhibitors*/Platelet Aggregation Inhibitors*/Platelet Aggregation Inhibitors*/administration & dosage ; Platelet Aggregation Inhibitors*/Platelet Aggregation Inhibitors*/Platelet Aggregation Inhibitors*/therapeutic use

  • Source: Stroke and vascular neurology [Stroke Vasc Neurol] 2024 Nov 05; Vol. 9 (5), pp. 541-550. Date of Electronic Publication: 2024 Nov 05.Publisher: BMJ Country of Publication: England NLM ID: 101689996 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-8696

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Academic Journal

Understanding Voriconazole Metabolism: A Middle-Out Physiologically-Based Pharmacokinetic Modelling Framework Integrating In Vitro and Clinical Insights.

  • Authors : Saleh A; Department of Clinical Pharmacy and Biochemistry, Institute of Pharmacy, Freie Universitaet Berlin, Berlin, Germany.; Graduate Research Training Program PharMetrX, Berlin/Potsdam, Germany.

Subjects: Voriconazole*/Voriconazole*/Voriconazole*/pharmacokinetics ; Antifungal Agents*/Antifungal Agents*/Antifungal Agents*/pharmacokinetics ; Models, Biological*

  • Source: Clinical pharmacokinetics [Clin Pharmacokinet] 2024 Nov; Vol. 63 (11), pp. 1609-1630. Date of Electronic Publication: 2024 Oct 30.Publisher: Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1926

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Academic Journal

Pharmacogenomics in psychiatry: Practice recommendations from an Asian perspective (2024).

Subjects: Psychiatry*/Psychiatry*/Psychiatry*/methods ; Pharmacogenetics* ; Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/genetics

  • Source: Annals of the Academy of Medicine, Singapore [Ann Acad Med Singap] 2024 Dec 26; Vol. 53 (12), pp. 734-741. Date of Electronic Publication: 2024 Dec 26.Publisher: Academy Of Medicine, Singapore Country of Publication: Singapore NLM ID: 7503289 Publication Model: Electronic Cited Medium: Internet

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  • 1-10 of  4,534 results for ""CYTOCHROME P-450 CYP2C19""