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Academic Journal

Versatile plant genome engineering using anti-CRISPR-Cas12a systems.

  • Authors : He Y; Integrative Science Center of Germplasm Creation in Western China (Chongqing) Science City, Chongqing Key Laboratory of Tree Germplasm Innovation and Utilization, School of Life Sciences, Southwest University, Chongqing, 400715, China.; Department of Biotechnology, School of Life Sciences and Technology, Center for Informational Biology, University of Electronic Science and Technology of China, Chengdu, 610054, China.

Subjects: CRISPR-Cas Systems* ; Gene Editing*/Gene Editing*/Gene Editing*/methods ; Genome, Plant*

  • Source: Science China. Life sciences [Sci China Life Sci] 2024 Dec; Vol. 67 (12), pp. 2730-2745. Date of Electronic Publication: 2024 Aug 15.Publisher: Science China Press, co-published with Springer Country of Publication: China NLM ID: 101529880 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Enhanced trans-cleavage activity using CRISPR-Cas12a variant designed to reduce steric inhibition by cis-cleavage products.

  • Authors : Hwang I; Cell Regeneration Research Center, Chonnam National University Hospital, Gwangju, Republic of Korea.; Song YH

Subjects: CRISPR-Cas Systems* ; Biosensing Techniques*/Biosensing Techniques*/Biosensing Techniques*/methods ; Hepatitis B virus*/Hepatitis B virus*/Hepatitis B virus*/genetics

  • Source: Biosensors & bioelectronics [Biosens Bioelectron] 2025 Jan 01; Vol. 267, pp. 116859. Date of Electronic Publication: 2024 Oct 16.Publisher: Elsevier Advanced Technology Country of Publication: England NLM ID: 9001289 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Thermodynamic parameters obtained for the formation of the Cas12a-RNA/DNA complex.

  • Authors : Baranova SV; Institute of Chemical Biology and Fundamental Medicine, SB RAS, 630090, Novosibirsk, Russia. Electronic address: .; Zhdanova PV

Subjects: Thermodynamics* ; Molecular Dynamics Simulation* ; DNA*/DNA*/DNA*/chemistry

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2025 Jan; Vol. 743, pp. 151176. Date of Electronic Publication: 2024 Dec 12.Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Cas12e orthologs evolve variable structural elements to facilitate dsDNA cleavage.

  • Authors : Li D; Beijing Frontier Research Center for Biological Structure, State Key Laboratory of Membrane Biology, School of Life Sciences, Tsinghua University, Beijing, 100084, China.; Tsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing, 100084, China.

Subjects: CRISPR-Cas Systems* ; DNA*/DNA*/DNA*/metabolism ; DNA*/DNA*/DNA*/genetics

  • Source: Nature communications [Nat Commun] 2024 Dec 30; Vol. 15 (1), pp. 10727. Date of Electronic Publication: 2024 Dec 30.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Interpreting CRISPR-Cas12a enzyme kinetics through free energy change of nucleic acids.

  • Authors : Zhang J; Department of Biomedical Engineering, University of Connecticut Health Center, Farmington, CT 06030, USA.; Department of Biomedical Engineering, University of Connecticut, Storrs, CT 06269, USA.

Subjects: CRISPR-Cas Systems* ; CRISPR-Associated Proteins*/CRISPR-Associated Proteins*/CRISPR-Associated Proteins*/metabolism ; CRISPR-Associated Proteins*/CRISPR-Associated Proteins*/CRISPR-Associated Proteins*/chemistry

  • Source: Nucleic acids research [Nucleic Acids Res] 2024 Dec 11; Vol. 52 (22), pp. 14077-14092.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

AcrIIIA1 is a protein-RNA anti-CRISPR complex that targets core Cas and accessory nucleases.

  • Authors : Chou-Zheng L; Department of Microbiology, University of Illinois, 601 S. Goodwin Avenue, Urbana, IL 61801, USA.; Howell O

Subjects: CRISPR-Associated Proteins*/CRISPR-Associated Proteins*/CRISPR-Associated Proteins*/metabolism ; CRISPR-Associated Proteins*/CRISPR-Associated Proteins*/CRISPR-Associated Proteins*/genetics ; CRISPR-Cas Systems*

  • Source: Nucleic acids research [Nucleic Acids Res] 2024 Dec 11; Vol. 52 (22), pp. 13490-13514.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Adaptive immunity of type VI CRISPR-Cas systems associated with reverse transcriptase-Cas1 fusion proteins.

  • Authors : Molina-Sánchez MD; Department of Soil and Plant Microbiology, Estación Experimental del Zaidín, Consejo Superior de Investigaciones Científicas, Structure, Dynamics and Function of Bacterial Genomes, Grupo de Ecología Genética de la Rizosfera, C/Profesor Albareda 1, 18008 Granada, Spain.; Martínez-Abarca F

Subjects: CRISPR-Cas Systems* ; RNA-Directed DNA Polymerase*/RNA-Directed DNA Polymerase*/RNA-Directed DNA Polymerase*/metabolism ; RNA-Directed DNA Polymerase*/RNA-Directed DNA Polymerase*/RNA-Directed DNA Polymerase*/genetics

  • Source: Nucleic acids research [Nucleic Acids Res] 2024 Dec 11; Vol. 52 (22), pp. 14229-14243.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Biochemical plasticity of the Escherichia coli CRISPR Cascade revealed by in vitro reconstitution of Cascade activities from purified Cas proteins.

  • Authors : Lemak S; Department of Chemical Engineering and Applied Chemistry, University of Toronto, Canada.; Brown G

Subjects: Escherichia coli*/Escherichia coli*/Escherichia coli*/genetics ; Escherichia coli*/Escherichia coli*/Escherichia coli*/metabolism ; Escherichia coli Proteins*/Escherichia coli Proteins*/Escherichia coli Proteins*/metabolism

  • Source: The FEBS journal [FEBS J] 2024 Dec; Vol. 291 (23), pp. 5177-5194. Date of Electronic Publication: 2024 Oct 07.Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication

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Academic Journal

Effects of steric hindrance from single-stranded overhangs on target-strand loading into the Cas12a active site.

  • Authors : Son H; Genome Editing Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.; Kang Y

Subjects: Catalytic Domain* ; CRISPR-Cas Systems* ; CRISPR-Associated Proteins*/CRISPR-Associated Proteins*/CRISPR-Associated Proteins*/metabolism

  • Source: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2024 Nov 05; Vol. 60 (89), pp. 13087-13090. Date of Electronic Publication: 2024 Nov 05.Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 9610838 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Cas1 mediates the interference stage in a phage-encoded CRISPR-Cas system.

  • Authors : Zhang L; Ministry of Education Key Laboratory of Protein Science, Beijing Advanced Innovation Center for Structural Biology, Beijing Frontier Research Center for Biological Structure, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China.; Wang H

Subjects: CRISPR-Cas Systems* ; Bacteriophages*/Bacteriophages*/Bacteriophages*/genetics ; CRISPR-Associated Proteins*/CRISPR-Associated Proteins*/CRISPR-Associated Proteins*/metabolism

  • Source: Nature chemical biology [Nat Chem Biol] 2024 Nov; Vol. 20 (11), pp. 1471-1481. Date of Electronic Publication: 2024 Jul 08.Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  5,656 results for ""CRISPR-Associated Proteins""