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Academic Journal

Multiresolution molecular dynamics simulations reveal the interplay between conformational variability and functional interactions in membrane-bound cytochrome P450 2B4.

  • Authors : Han SB; Molecular and Cellular Modeling Group, Heidelberg Institute for Theoretical Studies (HITS), Heidelberg, Germany.; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany.

Subjects: Aryl Hydrocarbon Hydroxylases*/Aryl Hydrocarbon Hydroxylases*/Aryl Hydrocarbon Hydroxylases*/chemistry ; Aryl Hydrocarbon Hydroxylases*/Aryl Hydrocarbon Hydroxylases*/Aryl Hydrocarbon Hydroxylases*/metabolism ; Cytochrome P450 Family 2*/Cytochrome P450 Family 2*/Cytochrome P450 Family 2*/chemistry

  • Source: Protein science : a publication of the Protein Society [Protein Sci] 2024 Oct; Vol. 33 (10), pp. e5165.Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 9211750 Publication Model: Print Cited Medium: Internet

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Academic Journal

A flexible linker of 8-amino acids between the membrane binding segment and the FMN domain of cytochrome P450 reductase is necessary for optimal activity.

  • Authors : Rwere F; Department of Anesthesiology, University of Michigan and VAMC, 2215 Fuller Road, Ann Arbor, MI, USA; Department of Anesthesiology, Perioperative and Pain Medicine, School of Medicine, Stanford University, 3174 Porter Dr, Palo Alto, CA, USA. Electronic address: .

Subjects: NADPH-Ferrihemoprotein Reductase*/NADPH-Ferrihemoprotein Reductase*/NADPH-Ferrihemoprotein Reductase*/metabolism ; NADPH-Ferrihemoprotein Reductase*/NADPH-Ferrihemoprotein Reductase*/NADPH-Ferrihemoprotein Reductase*/chemistry ; NADPH-Ferrihemoprotein Reductase*/NADPH-Ferrihemoprotein Reductase*/NADPH-Ferrihemoprotein Reductase*/genetics

  • Source: Journal of inorganic biochemistry [J Inorg Biochem] 2024 Oct; Vol. 259, pp. 112667. Date of Electronic Publication: 2024 Jul 16.Publisher: Elsevier Country of Publication: United States NLM ID: 7905788 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Identification of New Substrates and Inhibitors of Human CYP2A7.

  • Authors : Ashraf RA; School of Pharmaceutical Science and Technology, Faculty of Medicine, Tianjin University, Tianjin 300072, China.; Liu S

Subjects: Aryl Hydrocarbon Hydroxylases*/Aryl Hydrocarbon Hydroxylases*/Aryl Hydrocarbon Hydroxylases*/antagonists & inhibitors ; Aryl Hydrocarbon Hydroxylases*/Aryl Hydrocarbon Hydroxylases*/Aryl Hydrocarbon Hydroxylases*/genetics ; Aryl Hydrocarbon Hydroxylases*/Aryl Hydrocarbon Hydroxylases*/Aryl Hydrocarbon Hydroxylases*/metabolism

  • Source: Molecules (Basel, Switzerland) [Molecules] 2024 May 08; Vol. 29 (10). Date of Electronic Publication: 2024 May 08.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Circadian rhythms in CYP2A5 expression underlie the time-dependent effect of tegafur on breast cancer.

  • Authors : Yoshida Y; Department of Clinical Pharmacokinetics, Faculty of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi Higashi-ku, Fukuoka, 812-8582, Japan.; Fukuda T

Subjects: Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/drug therapy ; Aryl Hydrocarbon Hydroxylases*; Female

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2024 May 14; Vol. 708, pp. 149813. Date of Electronic Publication: 2024 Mar 20.Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Association between gene polymorphisms and initial warfarin therapy in patients after heart valve surgery.

  • Authors : Liu Z; Department of Laboratory Medicine, State Key Laboratory of Cardiovascular Disease, Beijing Key Laboratory for Molecular Diagnostics of Cardiovascular Diseases, Center of Laboratory Medicine, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.; Luo F

Subjects: Warfarin*/Warfarin*/Warfarin*/therapeutic use ; Aryl Hydrocarbon Hydroxylases*/Aryl Hydrocarbon Hydroxylases*/Aryl Hydrocarbon Hydroxylases*/genetics; Humans

  • Source: Pharmacological reports : PR [Pharmacol Rep] 2024 Apr; Vol. 76 (2), pp. 390-399. Date of Electronic Publication: 2024 Mar 08.Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101234999 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Influence of novel CYP2C-haplotype on proton pump inhibitor pharmacokinetics in children.

  • Authors : Kyler KE; Division of Hospital Medicine, Children's Mercy Kansas City, Kansas City, Missouri, USA.; School of Medicine, University of Missouri-Kansas City, Kansas City, Missouri, USA.

Subjects: Proton Pump Inhibitors*/Proton Pump Inhibitors*/Proton Pump Inhibitors*/pharmacokinetics ; Aryl Hydrocarbon Hydroxylases*/Aryl Hydrocarbon Hydroxylases*/Aryl Hydrocarbon Hydroxylases*/genetics ; Cytochrome P-450 Enzyme System*

  • Source: Clinical and translational science [Clin Transl Sci] 2024 Apr; Vol. 17 (4), pp. e13782.Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Association Study of Esomeprazole Pharmacokinetics and CYP2C19 Gene Polymorphisms.

  • Authors : Fang Y; Department of Gastroenterology, West China Hospital, Sichuan University, Wuhou, Chengdu, P.R. China.; Department of Clinical Research Management, West China Hospital, Sichuan University, Wuhou, Chengdu, P.R. China.

Subjects: Esomeprazole* ; Aryl Hydrocarbon Hydroxylases*/Aryl Hydrocarbon Hydroxylases*/Aryl Hydrocarbon Hydroxylases*/genetics ; Aryl Hydrocarbon Hydroxylases*/Aryl Hydrocarbon Hydroxylases*/Aryl Hydrocarbon Hydroxylases*/metabolism

  • Source: Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2024 Feb; Vol. 13 (2), pp. 134-139. Date of Electronic Publication: 2023 Sep 29.Publisher: Wiley Country of Publication: United States NLM ID: 101572899 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Clinical application of a real-time polymerase chain reaction test for CYP2C19 genotyping based on genotype distribution in a healthy Korean population.

  • Authors : Park K; Department of Laboratory Medicine, Sanggye Paik Hospital, School of Medicine, Inje University, Seoul, Republic of Korea.; Yoo SJ

Subjects: Aryl Hydrocarbon Hydroxylases*/Aryl Hydrocarbon Hydroxylases*/Aryl Hydrocarbon Hydroxylases*/genetics; Humans ; Genotype

  • Source: Laboratory medicine [Lab Med] 2024 Mar 07; Vol. 55 (2), pp. 234-237.Publisher: Oxford University Press Country of Publication: England NLM ID: 0250641 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

The metabolism of the orexin-1 selective receptor antagonist nivasorexant.

  • Authors : Treiber A; Department of Non-clinical Pharmacokinetics and Drug Metabolism, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland.; Seeland S

Subjects: Aryl Hydrocarbon Hydroxylases*/Aryl Hydrocarbon Hydroxylases*/Aryl Hydrocarbon Hydroxylases*/metabolism; Humans ; Rats

  • Source: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2024 Mar; Vol. 54 (3), pp. 124-137. Date of Electronic Publication: 2024 Mar 01.Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Chicken CYP1A5 is able to hydroxylate aflatoxin B 1 to aflatoxin M 1 .

  • Authors : Yuan Y; Institute of Plant Protection, Shandong Academy of Agricultural Sciences, Jinan, 250100, Shandong Province, China. Electronic address: .; Li M

Subjects: Aflatoxin B1*/Aflatoxin B1*/Aflatoxin B1*/metabolism ; Aflatoxin M1*/Aflatoxin M1*/Aflatoxin M1*/metabolism ; Aryl Hydrocarbon Hydroxylases*

  • Source: Toxicon : official journal of the International Society on Toxinology [Toxicon] 2024 Feb 23; Vol. 239, pp. 107625. Date of Electronic Publication: 2024 Jan 18.Publisher: Pergamon Press Country of Publication: England NLM ID: 1307333 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  12,475 results for ""Aryl Hydrocarbon Hydroxylases""