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Academic Journal

APOE from astrocytes restores Alzheimer's Aβ-pathology and DAM-like responses in APOE deficient microglia.

  • Authors : Preman P; VIB Center for Brain & Disease Research, Leuven, Belgium.; Laboratory for the Research of Neurodegenerative Diseases, Department of Neurosciences, Leuven Brain Institute (LBI), KU Leuven (University of Leuven), Leuven, Belgium.

Subjects: Astrocytes*/Astrocytes*/Astrocytes*/metabolism ; Astrocytes*/Astrocytes*/Astrocytes*/pathology ; Microglia*/Microglia*/Microglia*/metabolism

  • Source: EMBO molecular medicine [EMBO Mol Med] 2024 Dec; Vol. 16 (12), pp. 3113-3141. Date of Electronic Publication: 2024 Nov 11.Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Insufficient Mechanical Loading Downregulates Piezo1 in Chondrocytes and Impairs Fracture Healing Through ApoE-Induced Senescence.

  • Authors : Jia S; Department of Orthopaedic Surgery, NHC Key Laboratory of Intelligent Orthopaedic Equipment, Hebei Medical University Third Hospital, Shijiazhuang, Hebei, 050051, China.; Hebei Medical University Clinical Medicine Postdoctoral Station (Hebei Medical University Third Hospital), Shijiazhuang, Hebei, 050051, China.

Subjects: Chondrocytes*/Chondrocytes*/Chondrocytes*/metabolism ; Fracture Healing*/Fracture Healing*/Fracture Healing*/genetics ; Down-Regulation*

  • Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Dec; Vol. 11 (46), pp. e2400502. Date of Electronic Publication: 2024 Oct 17.Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844

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Academic Journal

Mulberroside A attenuates cigarette smoke-induced atherosclerosis in ApoE-/- mice via the Sirt1-HIF-1α axis.

  • Authors : Wang W; Faculty of Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa, Macau, China; Department of General Surgery (Vascular Surgery), The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan Province, China

Subjects: Sirtuin 1*/Sirtuin 1*/Sirtuin 1*/metabolism ; Atherosclerosis*/Atherosclerosis*/Atherosclerosis*/metabolism ; Atherosclerosis*/Atherosclerosis*/Atherosclerosis*/pathology

  • Source: Cellular signalling [Cell Signal] 2024 Dec; Vol. 124, pp. 111400. Date of Electronic Publication: 2024 Sep 12.Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 8904683 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Akkermansia Muciniphila supplementation improves hyperlipidemia, cardiac function, and gut microbiota in high fat fed apolipoprotein E-deficient mice.

  • Authors : Xiao X; Department of Pharmacy, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou 510080, China.; Wu Y

Subjects: Gastrointestinal Microbiome*/Gastrointestinal Microbiome*/Gastrointestinal Microbiome*/drug effects ; Akkermansia* ; Hyperlipidemias* Akkermansia muciniphila

  • Source: Prostaglandins & other lipid mediators [Prostaglandins Other Lipid Mediat] 2024 Dec; Vol. 175, pp. 106906. Date of Electronic Publication: 2024 Sep 11.Publisher: Elsevier Science Country of Publication: United States NLM ID: 9808648 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Hyperlipidemia and apolipoprotein E are associated with intraocular pressure of thyroid-associated ophthalmopathy in a Chinese population: a cross-sectional study.

  • Authors : Chen Y; Department of Endocrinology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.; Qi X

Subjects: Graves Ophthalmopathy*/Graves Ophthalmopathy*/Graves Ophthalmopathy*/blood ; Graves Ophthalmopathy*/Graves Ophthalmopathy*/Graves Ophthalmopathy*/epidemiology ; Hyperlipidemias*/Hyperlipidemias*/Hyperlipidemias*/blood

  • Source: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2024 Nov 28; Vol. 15, pp. 1484343. Date of Electronic Publication: 2024 Nov 28 (Print Publication: 2024).Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101555782 Publication Model: eCollection Cited Medium: Print

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Academic Journal

Dysregulated RBM24 phosphorylation impairs APOE translation underlying psychological stress-induced cardiovascular disease.

  • Authors : Yang H; College of Biomedicine and Health, College of Life science and Technology, Huazhong Agricultural University, Wuhan, 430070, China.; Sun L

Subjects: Stress, Psychological*/Stress, Psychological*/Stress, Psychological*/metabolism ; RNA-Binding Proteins*/RNA-Binding Proteins*/RNA-Binding Proteins*/metabolism ; RNA-Binding Proteins*/RNA-Binding Proteins*/RNA-Binding Proteins*/genetics

  • Source: Nature communications [Nat Commun] 2024 Nov 23; Vol. 15 (1), pp. 10181. Date of Electronic Publication: 2024 Nov 23.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Implications of the Lipidic Ecosystem for the Membrane Binding of ApoE Signal Peptide: Importance of Sphingomyelin.

  • Authors : Pradhan S; School of Chemistry, Sambalpur University, Jyoti Vihar, Burla, Odisha, 768019, India.; Mirdha L

Subjects: Sphingomyelins*/Sphingomyelins*/Sphingomyelins*/metabolism ; Sphingomyelins*/Sphingomyelins*/Sphingomyelins*/chemistry ; Apolipoproteins E*/Apolipoproteins E*/Apolipoproteins E*/metabolism

  • Source: Chembiochem : a European journal of chemical biology [Chembiochem] 2024 Nov 18; Vol. 25 (22), pp. e202400469. Date of Electronic Publication: 2024 Oct 23.Publisher: Wiley-VCH Verlag Country of Publication: Germany NLM ID: 100937360 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Complement and microglia activation mediate stress-induced synapse loss in layer 2/3 of the medial prefrontal cortex in male mice.

  • Authors : Tillmon H; Department of Pharmacology, University of Texas Health at San Antonio, San Antonio, TX, 78229, USA.; Soteros BM

Subjects: Microglia*/Microglia*/Microglia*/metabolism ; Microglia*/Microglia*/Microglia*/pathology ; Prefrontal Cortex*/Prefrontal Cortex*/Prefrontal Cortex*/pathology

  • Source: Nature communications [Nat Commun] 2024 Nov 12; Vol. 15 (1), pp. 9803. Date of Electronic Publication: 2024 Nov 12.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Apolipoprotein E aggregation in microglia initiates Alzheimer's disease pathology by seeding β-amyloidosis.

  • Authors : Kaji S; Institute of Neuronal Cell Biology, Technical University Munich, Munich, Germany; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/pathology ; Microglia*/Microglia*/Microglia*/metabolism

  • Source: Immunity [Immunity] 2024 Nov 12; Vol. 57 (11), pp. 2651-2668.e12. Date of Electronic Publication: 2024 Oct 16.Publisher: Cell Press Country of Publication: United States NLM ID: 9432918 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Therapeutic Challenges Derived from the Interaction Among Apolipoprotein E, Cholesterol, and Amyloid in Alzheimer's Disease.

  • Authors : Menendez-Gonzalez M; Departamento de Medicina, Facultad de Ciencias de la Salud, Universidad de Oviedo, ES-33006 Oviedo, Spain.; Servicio de Neurología, Hospital Universitario Central de Asturias, ES-33011 Oviedo, Spain.

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism ; Cholesterol*/Cholesterol*/Cholesterol*/metabolism ; Amyloid beta-Peptides*/Amyloid beta-Peptides*/Amyloid beta-Peptides*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Nov 08; Vol. 25 (22). Date of Electronic Publication: 2024 Nov 08.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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  • 1-10 of  51,523 results for ""Apolipoproteins E""