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Academic Journal

Shedding light into the biological activity of aminopterin, via molecular structural, docking, and molecular dynamics analyses.

  • Authors : Celik S; Physics Department, Science Faculty, Istanbul University, Istanbul, Turkey.; Yilmaz G

Subjects: Molecular Docking Simulation* ; Molecular Dynamics Simulation* ; Antiviral Agents*/Antiviral Agents*/Antiviral Agents*/chemistry

  • Source: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2024 Sep; Vol. 42 (15), pp. 7773-7794. Date of Electronic Publication: 2023 Aug 11.Publisher: Taylor & Francis Country of Publication: England NLM ID: 8404176 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

US Food and Drug Administration's Directive to Deal With Delayed Confirmatory Trials: Lessons From Pralatrexate and Belinostat for T-Cell Lymphoma.

  • Authors : Cliff ERS; Program On Regulation, Therapeutics, And Law, Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Boston, MA.; Harvard Medical School, Boston, MA.

Subjects: United States Food and Drug Administration* ; Aminopterin*/Aminopterin*/Aminopterin*/analogs & derivatives ; Aminopterin*/Aminopterin*/Aminopterin*/therapeutic use

  • Source: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2024 Nov 20; Vol. 42 (33), pp. 3901-3904. Date of Electronic Publication: Publisher: American Society of Clinical Oncology Country of Publication: United States NLM ID: 8309333 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Pooled analysis of pralatrexate single-agent studies in patients with relapsed/refractory peripheral T-cell lymphoma.

  • Authors : O'Connor OA; Division of Hematology-Oncology, University of Virginia Comprehensive Cancer Center, Translational Orphan Blood Cancer Research Center, University of Virginia, Charlottesville, VA.; Ko BS

Subjects: Aminopterin*/Aminopterin*/Aminopterin*/analogs & derivatives ; Aminopterin*/Aminopterin*/Aminopterin*/therapeutic use ; Lymphoma, T-Cell, Peripheral*/Lymphoma, T-Cell, Peripheral*/Lymphoma, T-Cell, Peripheral*/drug therapy

  • Source: Blood advances [Blood Adv] 2024 Jun 11; Vol. 8 (11), pp. 2601-2611.Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet

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Academic Journal

Phase II study of the novel antifolate agent pralatrexate in combination with the histone deacetylase inhibitor romidepsin for the treatment of patients with mature T-cell lymphoma.

  • Authors : Ryu Tiger YK; Division of Hematology and Oncology, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA.; Jain S

Subjects: Aminopterin*/Aminopterin*/Aminopterin*/analogs & derivatives ; Aminopterin*/Aminopterin*/Aminopterin*/therapeutic use ; Aminopterin*/Aminopterin*/Aminopterin*/administration & dosage

  • Source: Leukemia & lymphoma [Leuk Lymphoma] 2024 Jun; Vol. 65 (6), pp. 736-745. Date of Electronic Publication: 2024 Mar 22.Publisher: Taylor & Francis Country of Publication: United States NLM ID: 9007422 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Auxiliary in vitro and in vivo biological evaluation of hydrogen peroxide sensitive prodrugs of methotrexate and aminopterin for the treatment of rheumatoid arthritis.

  • Authors : Previtali V; Center for Nanomedicine & Theranostics, Department of Chemistry, Technical University of Denmark, Kemitorvet 207, DK-2800 Kongens Lyngby, Denmark.; Petrovic K

Subjects: Aminopterin/Aminopterin/Aminopterin/*pharmacology ; Antirheumatic Agents/Antirheumatic Agents/Antirheumatic Agents/*pharmacology ; Arthritis, Experimental/Arthritis, Experimental/Arthritis, Experimental/*drug therapy

  • Source: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2020 Jan 15; Vol. 28 (2), pp. 115247. Date of Electronic Publication: 2019 Dec 06.Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Pralatrexate inhibited the replication of varicella zoster virus and vesicular stomatitis virus: An old dog with new tricks.

  • Authors : Wu J; Medical School of Nanjing University, Nanjing, China.; Cai Y

Subjects: Vesicular Stomatitis*/Vesicular Stomatitis*/Vesicular Stomatitis*/drug therapy ; Herpes Zoster*/Herpes Zoster*/Herpes Zoster*/drug therapy; Aminopterin/Aminopterin/Aminopterin/*analogs & derivatives

  • Source: Antiviral research [Antiviral Res] 2024 Jan; Vol. 221, pp. 105787. Date of Electronic Publication: 2023 Dec 23.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8109699 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Efficacy and tolerability of folate-aminopterin therapy in a rat focal model of multiple sclerosis.

  • Authors : Elo P; Turku PET Centre, University of Turku, Turku, Finland.; Li XG

Subjects: Aminopterin/Aminopterin/Aminopterin/*pharmacology ; Encephalomyelitis, Autoimmune, Experimental/Encephalomyelitis, Autoimmune, Experimental/Encephalomyelitis, Autoimmune, Experimental/*pathology ; Folate Receptor 2/Folate Receptor 2/Folate Receptor 2/*metabolism

  • Source: Journal of neuroinflammation [J Neuroinflammation] 2021 Jan 20; Vol. 18 (1), pp. 30. Date of Electronic Publication: 2021 Jan 20.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

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Academic Journal

Pralatrexate Sustainably Released from Polypeptide Thermogel Is Effective for Chondrogenic Differentiation of Mesenchymal Stem Cells.

  • Authors : Woo Y; Department of Chemistry and Nanoscience, Ewha Womans University, 52 Ewhayeodae-gil, Seodaemun-gu, Seoul 03760, Korea.; Patel M

Subjects: Temperature*; Aminopterin/Aminopterin/Aminopterin/*analogs & derivatives ; Biocompatible Materials/Biocompatible Materials/Biocompatible Materials/*pharmacology

  • Source: ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2022 Jan 26; Vol. 14 (3), pp. 3773-3783. Date of Electronic Publication: 2022 Jan 11.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101504991 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Synthesis and Evaluation of Hydrogen Peroxide Sensitive Prodrugs of Methotrexate and Aminopterin for the Treatment of Rheumatoid Arthritis.

  • Authors : Peiró Cadahía J; Center for Nanomedicine & Theranostics, Department of Chemistry , Technical University of Denmark , Kemitorvet 207 , DK-2800 Kongens Lyngby , Denmark.; Bondebjerg J

Subjects: Aminopterin/Aminopterin/Aminopterin/*therapeutic use ; Antirheumatic Agents/Antirheumatic Agents/Antirheumatic Agents/*therapeutic use ; Arthritis, Rheumatoid/Arthritis, Rheumatoid/Arthritis, Rheumatoid/*drug therapy

  • Source: Journal of medicinal chemistry [J Med Chem] 2018 Apr 26; Vol. 61 (8), pp. 3503-3515. Date of Electronic Publication: 2018 Apr 10.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Complete remission of stage IV erythrodermic mycosis fungoides with large cell transformation through combination of pralatrexate and romidepsin followed by allogeneic hematopoietic stem cell transplantation.

  • Authors : Frederiks AJ; School of Medicine, University of Western Australia, Nedlands, Western Australia, Australia.; Department of Haematology, Royal Perth Hospital, Perth, Western Australia, Australia.

Subjects: Hematopoietic Stem Cell Transplantation*; Aminopterin/Aminopterin/Aminopterin/*analogs & derivatives ; Antibiotics, Antineoplastic/Antibiotics, Antineoplastic/Antibiotics, Antineoplastic/*therapeutic use

  • Source: The Australasian journal of dermatology [Australas J Dermatol] 2021 Aug; Vol. 62 (3), pp. e400-e403. Date of Electronic Publication: 2021 May 24.Publisher: Wiley-Blackwell Country of Publication: Australia NLM ID: 0135232 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  19,252 results for ""Aminopterin""