Search Results

Lysosomal cystine accumulation activates mTOR signaling in cystinosis: are mTOR inhibitors the cure?

• Authors : Christer S; Nephrogenetics Unit, Institute of Human Genetics, University Hospital Heidelberg, Heidelberg, Germany.; Simons M

Subjects: Cystinosis*/Cystinosis*/Cystinosis*/drug therapy ; Amino Acid Transport Systems, Neutral*; Humans

• Source: Kidney international [Kidney Int] 2024 Apr; Vol. 105 (4), pp. 656-658.Publisher: Elsevier Country of Publication: United States NLM ID: 0323470 Publication Model: Print Cited Medium: Internet ISSN: 1523-1755

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Enhanced systematic delivery of fluconazole-loaded biotin-glutathione functionalized chitosan-g-proline carrier into the infected retinitis treatment.

• Authors : Guo Q; Ophthalmology, Department of Inner Mongolia Chaoju Eye Hospital, Hohhot Inner Mongolia, Hohhot, 010050, China.; Li Z

Subjects: Amino Acid Transport Systems, Neutral* ; Antifungal Agents*/Antifungal Agents*/Antifungal Agents*/pharmacology ; Chitosan*

• Source: BMC ophthalmology [BMC Ophthalmol] 2024 Jan 30; Vol. 24 (1), pp. 48. Date of Electronic Publication: 2024 Jan 30.Publisher: BioMed Central Country of Publication: England NLM ID: 100967802 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2415

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Genome-Wide Identification of Proline Transporter Gene Family in Non-Heading Chinese Cabbage and Functional Analysis of BchProT1 under Heat Stress.

• Authors : Tian J; College of Horticulture, Fujian Agriculture and Forestry University, Fuzhou 350002, China.; Chang K

Subjects: Thermotolerance*/Thermotolerance*/Thermotolerance*/genetics ; Amino Acid Transport Systems, Neutral* ; Arabidopsis*/Arabidopsis*/Arabidopsis*/genetics

• Source: International journal of molecular sciences [Int J Mol Sci] 2023 Dec 20; Vol. 25 (1). Date of Electronic Publication: 2023 Dec 20.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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SLC38A5 Modulates Ferroptosis to Overcome Gemcitabine Resistance in Pancreatic Cancer.

• Authors : Kim MJ; Department of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06229, Republic of Korea.; Brain Korea 21 PLUS Project for Medical Science, Yonsei University, Seoul 03722, Republic of Korea.

Subjects: Ferroptosis* ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/drug therapy ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/genetics

• Source: Cells [Cells] 2023 Oct 23; Vol. 12 (20). Date of Electronic Publication: 2023 Oct 23.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Amino acid transporter SLC38A5 is a tumor promoter and a novel therapeutic target for pancreatic cancer.

• Authors : Sniegowski T; Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, TX, 79430, USA.; Rajasekaran D

Subjects: Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/pathology ; Carcinoma, Pancreatic Ductal*/Carcinoma, Pancreatic Ductal*/Carcinoma, Pancreatic Ductal*/pathology ; Amino Acid Transport Systems, Neutral*

• Source: Scientific reports [Sci Rep] 2023 Oct 06; Vol. 13 (1), pp. 16863. Date of Electronic Publication: 2023 Oct 06.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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SLC38A5 aggravates DC-mediated psoriasiform skin inflammation via potentiating lysosomal acidification.

• Authors : Zhu L; The Biomedical Translational Research Institute, Key Laboratory of Ministry of Education for Viral Pathogenesis & Infection Prevention and Control, Health Science Center (School of Medicine), Jinan University, Guangzhou 510632, China; Department of Dermatology, First Affiliated Hospital, Health Science Center (School of Medicine), Jinan University, Guangzhou 510632, China

Subjects: Psoriasis*/Psoriasis*/Psoriasis*/pathology ; Amino Acid Transport Systems, Neutral*; Animals

• Source: Cell reports [Cell Rep] 2023 Aug 29; Vol. 42 (8), pp. 112910. Date of Electronic Publication: 2023 Aug 01.Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Construction and validation of a prognostic model for colon adenocarcinoma based on bile acid metabolism-related genes.

• Authors : Luo Q; Department of Anorectal Surgery, Wuyi Hospital of Traditional Chinese Medicine, Jiangmen, China. .; Zhou P

Subjects: Adenocarcinoma*/Adenocarcinoma*/Adenocarcinoma*/genetics ; Colonic Neoplasms*/Colonic Neoplasms*/Colonic Neoplasms*/genetics ; Amino Acid Transport Systems, Neutral*

• Source: Scientific reports [Sci Rep] 2023 Aug 05; Vol. 13 (1), pp. 12728. Date of Electronic Publication: 2023 Aug 05.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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First person - Hartmut Cuny.

Subjects: Research Personnel* ; Amino Acid Transport Systems, Neutral*; Mice

• Source: Disease models & mechanisms [Dis Model Mech] 2023 May 01; Vol. 16 (5). Date of Electronic Publication: 2022 Nov 14.Publisher: Company of Biologists Ltd Country of Publication: England NLM ID: 101483332 Publication Model: Print-Electronic Cited Medium: Internet

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Sodium-Dependent Neutral Amino Acid Transporter 2 Can Serve as a Tertiary Carrier for l-Type Amino Acid Transporter 1-Utilizing Prodrugs.

• Authors : Huttunen J; School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland.; Kronenberger T

Subjects: Prodrugs*/Prodrugs*/Prodrugs*/chemistry ; Amino Acid Transport Systems, Neutral*; Humans

• Source: Molecular pharmaceutics [Mol Pharm] 2023 Feb 06; Vol. 20 (2), pp. 1331-1346. Date of Electronic Publication: 2023 Jan 23.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101197791 Publication Model: Print-Electronic Cited Medium: Internet

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Picornavirus infection enhances aspartate by the SLC38A8 transporter to promote viral replication.

• Authors : Liu H; State Key Laboratory of Veterinary Etiological Biology; College of Veterinary Medicine, Lanzhou University, WOAH/National reference laboratory for foot-and-mouth disease

Subjects: Enterovirus* ; Foot-and-Mouth Disease* ; Foot-and-Mouth Disease Virus*/Foot-and-Mouth Disease Virus*/Foot-and-Mouth Disease Virus*/metabolismSenecavirus A

• Source: PLoS pathogens [PLoS Pathog] 2023 Feb 03; Vol. 19 (2), pp. e1011126. Date of Electronic Publication: 2023 Feb 03 (Print Publication: 2023).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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CRRT 2023 Meeting: Targeting Amino Acid Transport to Improve Acute Kidney Injury Outcome.

• Authors : Oe Y; Department of Medicine, University of California San Diego, La Jolla, California, USA.; Veterans Affairs San Diego Healthcare System, San Diego, California, USA.

Subjects: Acute Kidney Injury*/Acute Kidney Injury*/Acute Kidney Injury*/therapy ; Acute Kidney Injury*/Acute Kidney Injury*/Acute Kidney Injury*/metabolism ; Amino Acid Transport Systems, Neutral*

• Source: Nephron [Nephron] 2023; Vol. 147 (12), pp. 774-777. Date of Electronic Publication: 2023 Jul 25.Publisher: Karger Country of Publication: Switzerland NLM ID: 0331777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2235-3186

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Amino acid transporter SLC38A5 regulates developmental and pathological retinal angiogenesis.

• Authors : Wang Z; Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, United States.; Yemanyi F

Subjects: Endothelial Cells* ; Amino Acid Transport Systems, Neutral*; Humans

• Source: ELife [Elife] 2022 Dec 01; Vol. 11. Date of Electronic Publication: 2022 Dec 01.Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet

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The SLC6A19 gene mutation in a young man with hyperglycinuria and nephrolithiasis: a case report and literature review.

• Authors : Pan Y; Department of Urology, Tianjin Medical University General Hospital, No. 154 Road Anshan, Heping District, 30052, Tianjin, China.; Wang S

Subjects: Kidney Calculi*/Kidney Calculi*/Kidney Calculi*/chemistry ; Urolithiasis*/Urolithiasis*/Urolithiasis*/complications ; Amino Acid Transport Systems, Neutral*Glycinuria with or without Oxalate Urolithiasis

• Source: BMC urology [BMC Urol] 2022 Nov 24; Vol. 22 (1), pp. 190. Date of Electronic Publication: 2022 Nov 24.Publisher: BioMed Central Country of Publication: England NLM ID: 100968571 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2490

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Further characterization of tryptophan metabolism and its dysregulation in fibroids.

• Authors : Chuang TD; Department of Obstetrics and Gynecology, Harbor-UCLA Medical Center and The Lundquist Institute, Torrance, California.; Quintanilla D

Subjects: Leiomyoma*/Leiomyoma*/Leiomyoma*/genetics ; Amino Acid Transport Systems, Neutral*; Humans

• Source: F&S science [F S Sci] 2022 Nov; Vol. 3 (4), pp. 392-400. Date of Electronic Publication: 2022 Apr 30.Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101765857 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Sleep disorders in McLeod syndrome: A case series.

• Authors : Lim MM; VA Portland Health Care System, Portland, OR, USA; Oregon Health & Science University, Department of Neurology, Portland, OR, USA

Subjects: Amino Acid Transport Systems, Neutral* ; Neuroacanthocytosis* ; Sleep Wake Disorders*/Sleep Wake Disorders*/Sleep Wake Disorders*/etiologyNeuroacanthocytosis, Mcleod Type

• Source: Parkinsonism & related disorders [Parkinsonism Relat Disord] 2022 Sep; Vol. 102, pp. 86-88. Date of Electronic Publication: 2022 Aug 09.Publisher: Elsevier Science Country of Publication: England NLM ID: 9513583 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Identification of the ataxin-1 interaction network and its impact on spinocerebellar ataxia type 1.

• Authors : Chen JM; Department of Laboratory Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201801, China.; Chen SK

Subjects: Amino Acid Transport Systems, Neutral* ; Spinocerebellar Ataxias*/Spinocerebellar Ataxias*/Spinocerebellar Ataxias*/genetics ; Spinocerebellar Ataxias*/Spinocerebellar Ataxias*/Spinocerebellar Ataxias*/pathology

• Source: Human genomics [Hum Genomics] 2022 Jul 29; Vol. 16 (1), pp. 29. Date of Electronic Publication: 2022 Jul 29.Publisher: BioMed Central Country of Publication: England NLM ID: 101202210 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-7364

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Neuropathology of McLeod Syndrome.

• Authors : Deutschländer AB; Department of Neurology, Mayo Clinic Florida, Jacksonville, Florida, USA.; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, Florida, USA.

Subjects: Amino Acid Transport Systems, Neutral* ; Nervous System Diseases* ; Neuroacanthocytosis*Neuroacanthocytosis, Mcleod Type

• Source: Movement disorders : official journal of the Movement Disorder Society [Mov Disord] 2022 Mar; Vol. 37 (3), pp. 644-646. Date of Electronic Publication: 2021 Dec 16.Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8610688 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Metabolomics of clinical samples reveal the treatment mechanism of lanthanum hydroxide on vascular calcification in chronic kidney disease.

• Authors : Gu C; Department of Pharmacology, College of Pharmacy, Inner Mongolian Medical University.; Gao Y

Subjects: Amino Acid Transport Systems, Neutral* ; Kidney Failure, Chronic*/Kidney Failure, Chronic*/Kidney Failure, Chronic*/complications ; Kidney Failure, Chronic*/Kidney Failure, Chronic*/Kidney Failure, Chronic*/drug therapy

• Source: Proceedings of the Japan Academy. Series B, Physical and biological sciences [Proc Jpn Acad Ser B Phys Biol Sci] 2022; Vol. 98 (7), pp. 361-377.Publisher: Japan Academy Country of Publication: Japan NLM ID: 9318162 Publication Model: Print Cited Medium: Internet ISSN: 1349-2896

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Six1 promotes skeletal muscle thyroid hormone response through regulation of the MCT10 transporter.

• Authors : Girgis J; Faculty of Medicine, Department of Biochemistry, Microbiology and Immunology, University of Ottawa, 451 Smyth Road, Ottawa, Ontario, K1H 8M5, Canada.; Ottawa Institute of Systems Biology, Ottawa, Ontario, Canada.

Subjects: Amino Acid Transport Systems, Neutral* ; Homeodomain Proteins*/Homeodomain Proteins*/Homeodomain Proteins*/genetics; Animals

• Source: Skeletal muscle [Skelet Muscle] 2021 Nov 19; Vol. 11 (1), pp. 26. Date of Electronic Publication: 2021 Nov 19.Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101561193 Publication Model: Electronic Cited Medium: Internet ISSN:

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Tissue-based metabolomics reveals metabolic biomarkers and potential therapeutic targets for esophageal squamous cell carcinoma.

• Authors : Chen Z; College of Pharmaceutical Sciences, Zhejiang University, Yuhangtang Road #866, Hangzhou, Zhejiang Province, 310058, China; Institute of Cancer and Basic Medicine (ICBM), Chinese Academy of Sciences, Banshandong Road#1, Hangzhou, Zhejiang Province, 310022, China

Subjects: Amino Acid Transport Systems, Neutral* ; Carcinoma, Squamous Cell*/Carcinoma, Squamous Cell*/Carcinoma, Squamous Cell*/drug therapy ; Esophageal Neoplasms*/Esophageal Neoplasms*/Esophageal Neoplasms*/drug therapy

• Source: Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2021 Apr 15; Vol. 197, pp. 113937. Date of Electronic Publication: 2021 Feb 05.Publisher: Elsevier Science Country of Publication: England NLM ID: 8309336 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Assessing the integrity of auditory processing and sensory memory in adults with cystinosis (CTNS gene mutations).

• Authors : Francisco AA; Department of Pediatrics, Albert Einstein College of Medicine, Van Etten Building, Suite 1C, 1225 Morris Park Avenue, Bronx, NY, 10461, USA. .; Berruti AS

Subjects: Amino Acid Transport Systems, Neutral* ; Cystinosis*; Adolescent

• Source: Orphanet journal of rare diseases [Orphanet J Rare Dis] 2021 Apr 13; Vol. 16 (1), pp. 177. Date of Electronic Publication: 2021 Apr 13.Publisher: BioMed Central Country of Publication: England NLM ID: 101266602 Publication Model: Electronic Cited Medium: Internet ISSN: 1750-1172

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From Genetics to Precision Therapy: Finding a Path through the Scientific Valley of Death.

• Authors : Gupta R; Rainbow Babies and Children's HospitalCase Western Reserve UniversityCleveland, Ohioand.; Gaston B

Subjects: Amino Acid Transport Systems, Neutral* ; Cystic Fibrosis*; Amino Acid Transport Systems

• Source: American journal of respiratory cell and molecular biology [Am J Respir Cell Mol Biol] 2019 Dec; Vol. 61 (6), pp. 671-672.Publisher: American Thoracic Society Country of Publication: United States NLM ID: 8917225 Publication Model: Print Cited Medium: Internet ISSN:

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Oh cystinosin: let me count the ways!

• Authors : Langman CB; Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA; The Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, USA. Electronic address: .

Subjects: Amino Acid Transport Systems, Neutral* ; Cystinosis*; Cystine

• Source: Kidney international [Kidney Int] 2019 Aug; Vol. 96 (2), pp. 275-277.Publisher: Elsevier Country of Publication: United States NLM ID: 0323470 Publication Model: Print Cited Medium: Internet ISSN: 1523-1755

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Spontaneously arising red cells with a McLeod-like phenotype in normal donors.

• Authors : Araten DJ; Division of Hematology, Department of Medicine, NYU School of Medicine, New York, NY, United States. ; Sanders KJ

Subjects: Amino Acid Transport Systems, Neutral* ; Blood Donors*; Erythrocytes/Erythrocytes/Erythrocytes/*metabolism

• Source: Mutation research [Mutat Res] 2009 Dec 01; Vol. 671 (1-2), pp. 1-5. Date of Electronic Publication: 2009 Apr 02.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0400763 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0027-5107

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Na+ and pH dependence of proline and beta-alanine absorption in rat small intestine.

• Authors : Iñigo C; Department of Physiology and Nutrition, University of Navarra, 31008 Pamplona, Spain.; Barber A

Subjects: Amino Acid Transport Systems/Amino Acid Transport Systems/Amino Acid Transport Systems/*metabolism ; Enterocytes/Enterocytes/Enterocytes/*metabolism ; Proline/Proline/Proline/*pharmacology

• Source: Acta physiologica (Oxford, England) [Acta Physiol (Oxf)] 2006 Apr; Vol. 186 (4), pp. 271-8.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101262545 Publication Model: Print Cited Medium: Print ISSN: 1748-1708 (Print)

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