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Academic Journal

Hope for vascular cognitive impairment: Ac-YVAD-cmk as a novel treatment against white matter rarefaction.

  • Authors : Lim YA; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Tan LS

Subjects: White Matter*/White Matter*/White Matter*/metabolism ; Cognitive Dysfunction* ; Amino Acid Chloromethyl Ketones*

  • Source: PloS one [PLoS One] 2024 Apr 17; Vol. 19 (4), pp. e0299703. Date of Electronic Publication: 2024 Apr 17 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Sarin-Induced Neuroinflammation in Mouse Brain Is Attenuated by the Caspase Inhibitor Q-VD-OPh.

  • Authors : Shah EJ; Departments of Pharmacology and Toxicology (E.J.S., W.C.G, T.L.G., D.R.C) and Neuroscience, Cell Biology and Physiology (T.L.G., T.L.B.), Wright State University, Dayton, Ohio.; Grunwald WC Jr

Subjects: Sarin*/Sarin*/Sarin*/toxicity ; Nerve Agents*/Nerve Agents*/Nerve Agents*/pharmacology ; Amino Acid Chloromethyl Ketones*

  • Source: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2024 Jan 17; Vol. 388 (2), pp. 367-375. Date of Electronic Publication: 2024 Jan 17.Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 0376362 Publication Model: Electronic

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Academic Journal

Identification of Kukoamine A, Zeaxanthin, and Clexane as New Furin Inhibitors.

  • Authors : Zaragoza-Huesca D; Servicio de Hematología y Oncología Médica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonación, CIBERER, Universidad de Murcia, IMIB-Arrixaca, 30003 Murcia, Spain.; Martínez-Cortés C

Subjects: Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*pharmacology ; Enoxaparin/Enoxaparin/Enoxaparin/*pharmacology ; Furin/Furin/Furin/*antagonists & inhibitors

  • Source: International journal of molecular sciences [Int J Mol Sci] 2022 Mar 03; Vol. 23 (5). Date of Electronic Publication: 2022 Mar 03.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Caspase-1 inhibition ameliorates murine acute graft versus host disease by modulating the Th1/Th17/Treg balance.

  • Authors : Chen W; Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China; Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China

Subjects: Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*therapeutic use ; Caspase 1/Caspase 1/Caspase 1/*immunology ; Graft vs Host Disease/Graft vs Host Disease/Graft vs Host Disease/*drug therapy

  • Source: International immunopharmacology [Int Immunopharmacol] 2021 May; Vol. 94, pp. 107503. Date of Electronic Publication: 2021 Feb 26.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Caspase-1/IL-1β represses membrane transport of GluA1 by inhibiting the interaction between Stargazin and GluA1 in Alzheimer's disease.

  • Authors : Gu X; Department of Neurology, The Second Affiliated Hospital of Nanchang University, No. 1 Minde Road, Nanchang, 330006, Jiangxi, China.; Wu H

Subjects: Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*drug therapy ; Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*administration & dosage ; Amyloid beta-Peptides/Amyloid beta-Peptides/Amyloid beta-Peptides/*adverse effects

  • Source: Molecular medicine (Cambridge, Mass.) [Mol Med] 2021 Jan 28; Vol. 27 (1), pp. 8. Date of Electronic Publication: 2021 Jan 28.Publisher: BioMed Central Country of Publication: England NLM ID: 9501023 Publication Model: Electronic Cited Medium: Internet ISSN: 1528-3658

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Academic Journal

Gasdermin E-derived caspase-3 inhibitors effectively protect mice from acute hepatic failure.

  • Authors : Xu WF; State Key Laboratory of Natural Medicines, Key Laboratory of Drug Metabolism, China Pharmaceutical University, Nanjing, 210009, China.; Zhang Q

Subjects: Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*therapeutic use ; Caspase 3/Caspase 3/Caspase 3/*metabolism ; Caspase Inhibitors/Caspase Inhibitors/Caspase Inhibitors/*therapeutic use

  • Source: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2021 Jan; Vol. 42 (1), pp. 68-76. Date of Electronic Publication: 2020 May 26.Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Peptidyl Fluoromethyl Ketones and Their Applications in Medicinal Chemistry.

  • Authors : Citarella A; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno D'Alcontres 31, I-98166 Messina, Italy.; Micale N

Subjects: Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*chemical synthesis ; Phenylalanine/Phenylalanine/Phenylalanine/*analogs & derivatives ; Severe acute respiratory syndrome-related coronavirus/Severe acute respiratory syndrome-related coronavirus/Severe acute respiratory syndrome-related coronavirus/*drug effects

  • Source: Molecules (Basel, Switzerland) [Molecules] 2020 Sep 03; Vol. 25 (17). Date of Electronic Publication: 2020 Sep 03.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Formulation and Characterization of Antithrombin Perfluorocarbon Nanoparticles.

  • Authors : Wilson AJ; The USF Health Heart Institute, University of South Florida, Tampa, FL, USA.; Zhou Q

Subjects: Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*chemical synthesis ; Antithrombins/Antithrombins/Antithrombins/*chemical synthesis ; Fluorocarbons/Fluorocarbons/Fluorocarbons/*chemistry

  • Source: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2020; Vol. 2118, pp. 111-120.Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029

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Academic Journal

Ac-YVAD-cmk improves neurological function by inhibiting caspase-1-mediated inflammatory response in the intracerebral hemorrhage of rats.

  • Authors : Liang H; Department of Neurosurgery, First Affiliated Hospital of Harbin Medical University, Harbin, P.R. China.; Sun Y

Subjects: Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*therapeutic use ; Anti-Inflammatory Agents/Anti-Inflammatory Agents/Anti-Inflammatory Agents/*therapeutic use ; Caspase 1/Caspase 1/Caspase 1/*immunology

  • Source: International immunopharmacology [Int Immunopharmacol] 2019 Oct; Vol. 75, pp. 105771. Date of Electronic Publication: 2019 Jul 25.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Eliminating the contribution of lipopolysaccharide to protein allergenicity in the human cell-line activation test (h-CLAT).

  • Authors : Kobayashi-Tsukumo H; Department of Chemical and Energy Engineering, Yokohama National University.; Division of Risk Assessment, National Institute of Health Sciences.

Subjects: Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/Amino Acid Chloromethyl Ketones/*pharmacology ; Hypersensitivity/Hypersensitivity/Hypersensitivity/*etiology ; Hypersensitivity/Hypersensitivity/Hypersensitivity/*immunology

  • Source: The Journal of toxicological sciences [J Toxicol Sci] 2019; Vol. 44 (4), pp. 283-297.Publisher: Doku Sayō Kenkyūkai Country of Publication: Japan NLM ID: 7805798 Publication Model: Print Cited Medium: Internet ISSN: 1880-3989

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  • 1-10 of  2,986 results for ""Amino Acid Chloromethyl Ketones""