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Academic Journal

Enhanced microglial dynamics and a paucity of tau seeding in the amyloid plaque microenvironment contribute to cognitive resilience in Alzheimer's disease.

  • Authors : Jury-Garfe N; Stark Neurosciences Research Institute, Indiana University School of Medicine, Neurosciences Research Building 214G, 320 West 15th Street, Indianapolis, IN, 46202, USA.; Department of Anatomy, Cell Biology and Physiology, Indiana University School of Medicine, Indianapolis, IN, USA.

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/pathology ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism ; Microglia*/Microglia*/Microglia*/metabolism

  • Source: Acta neuropathologica [Acta Neuropathol] 2024 Aug 05; Vol. 148 (1), pp. 15. Date of Electronic Publication: 2024 Aug 05.Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0533

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Academic Journal

Microglia-astrocyte crosstalk in the amyloid plaque niche of an Alzheimer's disease mouse model, as revealed by spatial transcriptomics.

  • Authors : Mallach A; UK Dementia Research Institute at UCL, University College London, London WC1E 6BT, UK; The Francis Crick Institute, London NW1 1AT, UK

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/pathology ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/genetics

  • Source: Cell reports [Cell Rep] 2024 Jun 25; Vol. 43 (6), pp. 114216. Date of Electronic Publication: 2024 May 30.Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Microglia and amyloid plaque formation in Alzheimer's disease - Evidence, possible mechanisms, and future challenges.

  • Authors : Fruhwürth S; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden. Electronic address: .; Zetterberg H

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/pathology ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/genetics

  • Source: Journal of neuroimmunology [J Neuroimmunol] 2024 May 15; Vol. 390, pp. 578342. Date of Electronic Publication: 2024 Apr 04.Publisher: Elsevier/North-Holland Country of Publication: Netherlands NLM ID: 8109498 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Transcriptome and Animal Model Integration Reveals Inhibition of Calcium Homeostasis-Associated Gene ITPKB Alleviates Amyloid Plaque Deposition.

  • Authors : Hu Y; Department of Anesthesiology, the Third Hospital of Hebei Medical University, 139 Ziqiang Road, Hebei, 050051, China.; Zhao Z

Subjects: Plaque, Amyloid*/Plaque, Amyloid*/Plaque, Amyloid*/genetics ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/genetics; Animals

  • Source: Journal of molecular neuroscience : MN [J Mol Neurosci] 2024 Apr 13; Vol. 74 (2), pp. 42. Date of Electronic Publication: 2024 Apr 13.Publisher: Humana Press Country of Publication: United States NLM ID: 9002991 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Mining the amyloid-plaque proteome to uncover disease mechanisms in renal amyloidoses.

  • Authors : Nuvolone M; Department of Molecular Medicine, University of Pavia, Pavia, Italy; Amyloidosis Research and Treatment Center, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

Subjects: Plaque, Amyloid* ; Amyloidosis*; Humans

  • Source: Kidney international [Kidney Int] 2024 Mar; Vol. 105 (3), pp. 427-429.Publisher: Elsevier Country of Publication: United States NLM ID: 0323470 Publication Model: Print Cited Medium: Internet ISSN: 1523-1755

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Academic Journal

The mitochondria-targeted small molecule SS31 delays progression of behavioral deficits by attenuating β-amyloid plaque formation and mitochondrial/synaptic deterioration in APP/PS1 mice.

  • Authors : Jia YL; Department of Graduate School, Hebei Medical University, Shijiazhuang, Hebei, 050051, China; Department of Neurology, Hebei General Hospital, Shijiazhuang, Hebei, 050051, China.

Subjects: Plaque, Amyloid*/Plaque, Amyloid*/Plaque, Amyloid*/drug therapy ; Plaque, Amyloid*/Plaque, Amyloid*/Plaque, Amyloid*/metabolism ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/drug therapy

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2023 May 28; Vol. 658, pp. 36-43. Date of Electronic Publication: 2023 Feb 28.Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Specific associations between plasma biomarkers and postmortem amyloid plaque and tau tangle loads.

  • Authors : Salvadó G; Clinical Memory Research Unit, Department of Clinical Sciences, Malmö, Lund University, Lund, Sweden.; Ossenkoppele R

Subjects: Plaque, Amyloid* ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/diagnosis; Humans

  • Source: EMBO molecular medicine [EMBO Mol Med] 2023 May 08; Vol. 15 (5), pp. e17123. Date of Electronic Publication: 2023 Mar 13.Publisher: EMBO Press Country of Publication: England NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Periodical

Stopping Alzheimer's Before It Starts.

Subjects: CLINICAL drug trials; AMYLOID plaque; ALZHEIMER'S diseaseELI Lilly & Co. ELI Lilly & Co. ELI Lilly & Co. LLY; EISAI Co. Ltd. EISAI Co. Ltd. EISAI Co. Ltd. 189246791

  • Source: Bloomberg Businessweek. 12/26/2022, Issue 4767, p10-12. 3p. 1 Color Photograph, 1 Diagram, 1 Cartoon or Caricature.

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Academic Journal

Of dolphins, humans, other long‐lived animals and Alzheimer's disease (Commentary on Vacher et al.).

Subjects: ALZHEIMER'S disease; AMYLOID plaque; DOLPHINS

  • Source: European Journal of Neuroscience. Apr2023, Vol. 57 Issue 7, p1180-1183. 4p. 1 Chart.

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Academic Journal

Microglial mTOR Activation Upregulates Trem2 and Enhances β-Amyloid Plaque Clearance in the 5XFAD Alzheimer's Disease Model.

  • Authors : Shi Q; Department of Cellular and Integrative Physiology, Long School of Medicine, University of Texas Health Science Center, San Antonio, Texas 78229.; Chang C

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism ; Membrane Glycoproteins*/Membrane Glycoproteins*/Membrane Glycoproteins*/genetics ; Membrane Glycoproteins*/Membrane Glycoproteins*/Membrane Glycoproteins*/metabolism

  • Source: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2022 Jul 06; Vol. 42 (27), pp. 5294-5313. Date of Electronic Publication: 2022 Jun Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Print-Electronic Cited Medium: Internet

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  • 1-10 of  56,128 results for ""AMYLOID plaque""