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Academic Journal

Intra-striatal infusion of the small molecule alpha-synuclein aggregator, FN075, does not enhance parkinsonism in a subclinical AAV-alpha-synuclein rat model.

  • Authors : Patton T; Pharmacology & Therapeutics and Galway Neuroscience Centre, University of Galway, Galway, Ireland.; Comini G

Subjects: alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/metabolism ; alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/genetics ; alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/administration & dosage

  • Source: The European journal of neuroscience [Eur J Neurosci] 2024 Sep; Vol. 60 (6), pp. 5234-5248. Date of Electronic Publication: 2024 Aug 14.Publisher: Wiley-Blackwell Country of Publication: France NLM ID: 8918110 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Liquid-liquid phase separation of alpha-synuclein increases the structural variability of fibrils formed during amyloid aggregation.

  • Authors : Ziaunys M; Institute of Biotechnology, Life Sciences Center, Vilnius University, Lithuania.; Sulskis D

Subjects: alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/chemistry ; alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/metabolism ; alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/genetics

  • Source: The FEBS journal [FEBS J] 2024 Oct; Vol. 291 (20), pp. 4522-4538. Date of Electronic Publication: 2024 Aug 08.Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication

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Academic Journal

The role of polo-like kinases 2 in the proteasomal and lysosomal degradation of alpha-synuclein in neurons.

  • Authors : Sung CC; Division of Life Science, State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Hong Kong, China.; Lam WY

Subjects: alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/metabolism ; alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/genetics ; Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/metabolism

  • Source: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2024 Oct; Vol. 38 (20), pp. e70121.Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print Cited

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Academic Journal

Possible regulation of the immune modulator tetraspanin CD81 by alpha-synuclein in melanoma.

  • Authors : Aloy NM; Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, LA, USA; Feist-Weiller Cancer Center, Louisiana State University Health Shreveport, Shreveport, USA.

Subjects: Melanoma*/Melanoma*/Melanoma*/immunology ; Melanoma*/Melanoma*/Melanoma*/metabolism ; Melanoma*/Melanoma*/Melanoma*/genetics

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2024 Nov 19; Vol. 734, pp. 150631. Date of Electronic Publication: 2024 Aug 30.Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Efficient characterization of multiple binding sites of small molecule imaging ligands on amyloid-beta, tau and alpha-synuclein.

  • Authors : Sobek J; Functional Genomics Center, University of Zurich & ETH Zurich, Zürich, Switzerland.; Li J

Subjects: alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/metabolism ; alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/chemistry ; tau Proteins*/tau Proteins*/tau Proteins*/metabolism

  • Source: European journal of nuclear medicine and molecular imaging [Eur J Nucl Med Mol Imaging] 2024 Nov; Vol. 51 (13), pp. 3960-3977. Date of Electronic Publication: 2024 Jul 02.Publisher: Springer-Verlag Berlin Country of Publication: Germany NLM ID: 101140988 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Synthesis and Semi-Synthesis of Alpha-Synuclein: Insight into the Chemical Complexity of Synucleinopathies.

  • Authors : Gatzemeier LM; Institute of Organic and Biomolecular Chemistry, University of Göttingen, Tammannstraße 2, 37077, Göttingen, Germany.; Department of Experimental Neurodegeneration, Center for Biostructural Imaging of Neurodegeneration, University Medical Center Göttingen, Waldweg 33, 37073, Göttingen, Germany.

Subjects: alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/metabolism ; alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/chemistry ; Synucleinopathies*/Synucleinopathies*/Synucleinopathies*/metabolism

  • Source: Chembiochem : a European journal of chemical biology [Chembiochem] 2024 Oct 16; Vol. 25 (20), pp. e202400253. Date of Electronic Publication: 2024 Aug 23.Publisher: Wiley-VCH Verlag Country of Publication: Germany NLM ID: 100937360 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The Alpha-Synuclein Gene (SNCA) is a Genomic Target of Methyl-CpG Binding Protein 2 (MeCP2)-Implications for Parkinson's Disease and Rett Syndrome.

  • Authors : Schmitt I; Department of Neurology, University of Bonn, Bonn, Germany.; German Centre for Neurodegenerative Disease (DZNE), Bonn, Germany.

Subjects: Methyl-CpG-Binding Protein 2*/Methyl-CpG-Binding Protein 2*/Methyl-CpG-Binding Protein 2*/genetics ; Methyl-CpG-Binding Protein 2*/Methyl-CpG-Binding Protein 2*/Methyl-CpG-Binding Protein 2*/metabolism ; alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/metabolism

  • Source: Molecular neurobiology [Mol Neurobiol] 2024 Oct; Vol. 61 (10), pp. 7830-7844. Date of Electronic Publication: 2024 Mar 02.Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Olfactory deficit and gastrointestinal dysfunction precede motor abnormalities in alpha-Synuclein G51D knock-in mice.

  • Authors : Kim Y; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030.; Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, TX 77030.

Subjects: alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/metabolism ; alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/genetics ; Parkinson Disease*/Parkinson Disease*/Parkinson Disease*/genetics

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Sep 24; Vol. 121 (39), pp. e2406479121. Date of Electronic Publication: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Non-coding RNAs in Parkinson's disease: Regulating SNCA and alpha-synuclein aggregation.

  • Authors : Thangavelu L; Centre for Global Health Research, Saveetha Medical College, Saveetha Institute of Medical and Technical Sciences, India.; Moglad E

Subjects: alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/metabolism ; alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/genetics ; Parkinson Disease*/Parkinson Disease*/Parkinson Disease*/genetics

  • Source: Pathology, research and practice [Pathol Res Pract] 2024 Sep; Vol. 261, pp. 155511. Date of Electronic Publication: 2024 Jul 30.Publisher: Gustav Fischer Verlag Country of Publication: Germany NLM ID: 7806109 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Alpha-synuclein and RNA viruses: Exploring the neuronal nexus.

  • Authors : Gupta A; Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, 781039, Assam, India.; Bohara VS

Subjects: alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/metabolism ; alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/genetics ; RNA Viruses*/RNA Viruses*/RNA Viruses*/physiology

  • Source: Virology [Virology] 2024 Sep; Vol. 597, pp. 110141. Date of Electronic Publication: 2024 Jun 15.Publisher: Academic Press Country of Publication: United States NLM ID: 0110674 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  107,566 results for ""ALPHA-synuclein""