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Academic Journal

A comparison of aminoglycoside antibiotic serum concentrations collected by peripheral veins and peripherally inserted central catheters in adults with cystic fibrosis.

Authors : Sherwood SJ; The Cystic Fibrosis Center of Idaho, St. Luke's Health System, Boise, Idaho, USA.; Tak C

Subjects: Cystic Fibrosis*/Cystic Fibrosis*/Cystic Fibrosis*/blood ; Cystic Fibrosis*/Cystic Fibrosis*/Cystic Fibrosis*/complications ; Cystic Fibrosis*/Cystic Fibrosis*/Cystic Fibrosis*/drug therapy

Source: Pediatric pulmonology [Pediatr Pulmonol] 2024 Jun; Vol. 59 (6), pp. 1740-1746. Date of Electronic Publication: 2024 Mar 19.Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8510590 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

An Antibiotic Nanobomb Constructed from pH-Responsive Chemical Bonds in Metal-Phenolic Network Nanoparticles for Biofilm Eradication and Corneal Ulcer Healing.

Authors : Gao Q; National Engineering Research Center of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou, 325000, P. R. China.; State Key Laboratory of Ophthalmology, Optometry and Visual Science, Wenzhou Medical University, Wenzhou, 325027, P. R. China.

Subjects: Biofilms*/Biofilms*/Biofilms*/drug effects ; Corneal Ulcer*/Corneal Ulcer*/Corneal Ulcer*/drug therapy ; Anti-Bacterial Agents*/Anti-Bacterial Agents*/Anti-Bacterial Agents*/pharmacology

Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Jun; Vol. 11 (22), pp. e2309086. Date of Electronic Publication: 2024 Mar 15.Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844

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Academic Journal

Clinical features and comprehensive treatment of persistent corneal epithelial dysfunction after cataract surgery.

Authors : Xiao X; Xiamen Eye Center and Eye Institute of Xiamen University, Xiamen, China.; Xiamen Clinical Research Center for Eye Diseases, Xiamen, Fujian, China.

Subjects: Dexamethasone*/Dexamethasone*/Dexamethasone*/therapeutic use ; Dexamethasone*/Dexamethasone*/Dexamethasone*/administration & dosage ; Epithelium, Corneal*/Epithelium, Corneal*/Epithelium, Corneal*/pathology

Source: BMC ophthalmology [BMC Ophthalmol] 2024 Apr 26; Vol. 24 (1), pp. 197. Date of Electronic Publication: 2024 Apr 26.Publisher: BioMed Central Country of Publication: England NLM ID: 100967802 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2415

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Academic Journal

Analyzing the Activity of Micafungin Combined with Tobramycin Against Pseudomonas Aeruginosa Biofilm.

Authors : Li YH; Zhang SX; Yang Y

Subjects: Tobramycin* ; Pseudomonas aeruginosa*; Humans

Source: Clinical laboratory [Clin Lab] 2023 Jun 01; Vol. 69 (6).Publisher: Clinical Laboratory Publications Country of Publication: Germany NLM ID: 9705611 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Chimeric Tobramycin-Based Adjuvant TOB-TOB-CIP Potentiates Fluoroquinolone and β-Lactam Antibiotics against Multidrug-Resistant Pseudomonas aeruginosa .

Authors : Dhiman S; Department of Chemistry, University of Manitoba, Winnipeg R3T 2N2, Manitoba, Canada.; Ramirez D

Subjects: Tobramycin*/Tobramycin*/Tobramycin*/pharmacology ; Ceftazidime*; Pseudomonas aeruginosa/Pseudomonas aeruginosa/Pseudomonas aeruginosa/genetics

Source: ACS infectious diseases [ACS Infect Dis] 2023 Apr 14; Vol. 9 (4), pp. 864-885. Date of Electronic Publication: 2023 Mar 14.Publisher: ACS Publications Country of Publication: United States NLM ID: 101654580 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Synergistic interaction of cuminaldehyde and tobramycin: a potential strategy for the efficient management of biofilm caused by Pseudomonas aeruginosa.

Authors : Chatterjee S; Department of Biotechnology, The Neotia University, Sarisha, West Bengal, 743368, India.; Das S

Subjects: Tobramycin*/Tobramycin*/Tobramycin*/pharmacology ; Pseudomonas Infections*; Humans

Source: Folia microbiologica [Folia Microbiol (Praha)] 2023 Feb; Vol. 68 (1), pp. 151-163. Date of Electronic Publication: 2022 Oct 04.Publisher: Springer Country of Publication: United States NLM ID: 0376757 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Dual action of benzaldehydes: Inhibiting quorum sensing and enhancing antibiotic efficacy for controlling Pseudomonas aeruginosa biofilms.

Authors : Leitão MM; LEPABE-Laboratory for Process Engineering, Environment, Biotechnology and Energy, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465, Porto, Portugal; ALICE-Associate Laboratory for Innovation in Chemical Engineering, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, s/n, 4200-465, Porto, Portugal

Subjects: Biofilms*/Biofilms*/Biofilms*/drug effects ; Quorum Sensing*/Quorum Sensing*/Quorum Sensing*/drug effects ; Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/drug effects

Source: Microbial pathogenesis [Microb Pathog] 2024 Jun; Vol. 191, pp. 106663. Date of Electronic Publication: 2024 Apr 26.Publisher: Academic Press Country of Publication: England NLM ID: 8606191 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

P. aeruginosa tRNA-fMet halves secreted in outer membrane vesicles suppress lung inflammation in cystic fibrosis.

Authors : Li Z; Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States.; Barnaby R

Subjects: Cystic Fibrosis*/Cystic Fibrosis*/Cystic Fibrosis*/microbiology ; Cystic Fibrosis*/Cystic Fibrosis*/Cystic Fibrosis*/metabolism ; Cystic Fibrosis*/Cystic Fibrosis*/Cystic Fibrosis*/pathology

Source: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2024 May 01; Vol. 326 (5), pp. L574-L588. Date of Electronic Publication: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901229 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Adaptation of Pseudomonas aeruginosa biofilms to tobramycin and the quorum sensing inhibitor C-30 during experimental evolution requires multiple genotypic and phenotypic changes.

Authors : Bové M; Laboratory of Pharmaceutical Microbiology, Ghent University, Ghent, Belgium.; Kolpen M

Subjects: Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/metabolism ; Tobramycin*/Tobramycin*/Tobramycin*/pharmacology ; Tobramycin*/Tobramycin*/Tobramycin*/metabolism

Source: Microbiology (Reading, England) [Microbiology (Reading)] 2023 Jan; Vol. 169 (1).Publisher: Microbiology Society Country of Publication: England NLM ID: 9430468 Publication Model: Print Cited Medium: Internet ISSN: 1465-2080

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Academic Journal

Tobramycin Nanoantibiotics and Their Advantages: A Minireview.

Authors : Rosalia M; Department of Drug Sciences, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.; Chiesa E

Subjects: Tobramycin*/Tobramycin*/Tobramycin*/pharmacology ; Tobramycin*/Tobramycin*/Tobramycin*/therapeutic use ; Gentamicins*

Source: International journal of molecular sciences [Int J Mol Sci] 2022 Nov 15; Vol. 23 (22). Date of Electronic Publication: 2022 Nov 15.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Assessing tobramycin levels and renal function following the implantation of CaSO4 beads impregnated with tobramycin: A prospective cohort study.

Authors : Alowais SA; Department of Pharmacy Practice, College of Pharmacy, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.; King Abdulaziz Medical City, National Guard Health Affairs, Riyadh, Saudi Arabia.

Subjects: Tobramycin* ; Anti-Bacterial Agents*/Anti-Bacterial Agents*/Anti-Bacterial Agents*/therapeutic use; Humans

Source: Medicine [Medicine (Baltimore)] 2022 Dec 09; Vol. 101 (49), pp. e32276.Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 2985248R Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

High efficiency of in-situ cross-linking and acid triggered drug delivery by introducing tobramycin into injectable and biodegradable hydrogels.

Authors : Xu K; Key Laboratory of Advanced Textile Materials & Manufacturing Technology, Ministry of Education, Zhejiang Sci-Tech University, 310018 Hangzhou, China; College of Life Science and Medicine, Zhejiang Sci-Tech University, 310018 Hangzhou, China.

Subjects: Hydrogels*/Hydrogels*/Hydrogels*/chemistry ; Tobramycin*/Tobramycin*/Tobramycin*/pharmacology; Aldehydes

Source: Colloids and surfaces. B, Biointerfaces [Colloids Surf B Biointerfaces] 2022 Oct; Vol. 218, pp. 112756. Date of Electronic Publication: 2022 Aug 10.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9315133 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Improved Aerosolization Stability of Inhalable Tobramycin Powder Formulation by Co-Spray Drying with Colistin.

Authors : Pathak V; Department of Industrial and Physical Pharmacy, College of Pharmacy, Purdue University, 575 Stadium Mall Drive, West Lafayette, IN, 47907, USA.; Park H

Subjects: Colistin*/Colistin*/Colistin*/chemistry ; Tobramycin*; Powders/Powders/Powders/chemistry

Source: Pharmaceutical research [Pharm Res] 2022 Nov; Vol. 39 (11), pp. 2781-2799. Date of Electronic Publication: 2022 Aug 02.Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 8406521 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Tobramycin-loaded complexes to prevent and disrupt Pseudomonas aeruginosa biofilms.

Authors : Boffoli D; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, via F. Marzolo 5, 35131, Padova, Italy.; Bellato F

Subjects: Pseudomonas aeruginosa* ; Tobramycin*/Tobramycin*/Tobramycin*/chemistry; Anti-Bacterial Agents/Anti-Bacterial Agents/Anti-Bacterial Agents/chemistry

Source: Drug delivery and translational research [Drug Deliv Transl Res] 2022 Aug; Vol. 12 (8), pp. 1788-1810. Date of Electronic Publication: 2021 Nov 28.Publisher: Springer Country of Publication: United States NLM ID: 101540061 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Bacteria can compensate the fitness costs of amplified resistance genes via a bypass mechanism.

Authors : Pal A; Department of Medical Biochemistry and Microbiology, Uppsala University, Box 582, SE-751 23, Uppsala, Sweden.; Andersson DI

Subjects: Anti-Bacterial Agents*/Anti-Bacterial Agents*/Anti-Bacterial Agents*/pharmacology ; Anti-Bacterial Agents*/Anti-Bacterial Agents*/Anti-Bacterial Agents*/therapeutic use ; Tobramycin*

Source: Nature communications [Nat Commun] 2024 Mar 14; Vol. 15 (1), pp. 2333. Date of Electronic Publication: 2024 Mar 14.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Development of excipients free inhalable co-spray-dried tobramycin and diclofenac formulations for cystic fibrosis using two and three fluid nozzles.

Authors : Marasini N; Respiratory Technology, Woolcock Institute of Medical Research, Glebe, Sydney, NSW 2037, Australia.; Sheikh Z

Subjects: Cystic Fibrosis*/Cystic Fibrosis*/Cystic Fibrosis*/drug therapy ; Tobramycin*; Administration, Inhalation

Source: International journal of pharmaceutics [Int J Pharm] 2022 Aug 25; Vol. 624, pp. 121989. Date of Electronic Publication: 2022 Jul 06.Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Electrochemical Quantification of Tobramycin Retention in Pseudomonas aeruginosa as Antimicrobial Susceptibility Indicator.

Authors : Clarindo Lopes L; Department of Chemistry, University of Manitoba, Winnipeg, Manitoba R3T 2N2, Canada.; Lima D

Subjects: Pseudomonas Infections*/Pseudomonas Infections*/Pseudomonas Infections*/drug therapy ; Pseudomonas Infections*/Pseudomonas Infections*/Pseudomonas Infections*/microbiology ; Tobramycin*/Tobramycin*/Tobramycin*/pharmacology

Source: Analytical chemistry [Anal Chem] 2022 Sep 20; Vol. 94 (37), pp. 12553-12558. Date of Electronic Publication: 2022 Sep 06.Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370536 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Fluorescence-polarization immunoassays within glass fiber micro-chambers enable tobramycin quantification in whole blood for therapeutic drug monitoring at the point of care.

Authors : Bojescu ED; Institute of Life Technologies - School of Engineering, HES-SO // University of Applied Sciences Western Switzerland, Sion, Switzerland. Electronic address: .; Prim D

Subjects: Drug Monitoring* ; Tobramycin*; Fluorescence Polarization Immunoassay/Fluorescence Polarization Immunoassay/Fluorescence Polarization Immunoassay/methods

Source: Analytica chimica acta [Anal Chim Acta] 2022 Sep 08; Vol. 1225, pp. 340240. Date of Electronic Publication: 2022 Aug 08.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0370534 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Neutralization of ionic interactions by dextran-based single-chain nanoparticles improves tobramycin diffusion into a mature biofilm.

Authors : Blanco-Cabra N; Bacterial Infections: Antimicrobial Therapies group, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain. .; Microbiology Section, Department of Genetics, Microbiology, and Statistics, Biology Faculty, Universitat de Barcelona, Barcelona, Spain. .

Subjects: Nanoparticles* ; Tobramycin*/Tobramycin*/Tobramycin*/pharmacology; Anti-Bacterial Agents/Anti-Bacterial Agents/Anti-Bacterial Agents/pharmacology

Source: NPJ biofilms and microbiomes [NPJ Biofilms Microbiomes] 2022 Jul 04; Vol. 8 (1), pp. 52. Date of Electronic Publication: 2022 Jul 04.Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101666944 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Temporal impacts of topical ceftazidime and tobramycin-vancomycin mixtures on the ocular surface microbiota in rabbits.

Authors : Xue R; Zhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Sun Yat-sen University, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China.; Liu Q

Subjects: Microbiota*/Microbiota*/Microbiota*/genetics ; Tobramycin*; Animals

Source: Experimental eye research [Exp Eye Res] 2022 Jul; Vol. 220, pp. 109098. Date of Electronic Publication: 2022 May 02.Publisher: Academic Press Country of Publication: England NLM ID: 0370707 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Consideration of height-based tobramycin dosing regimens for the treatment of adult cystic fibrosis pulmonary exacerbations.

Authors : El Hassani M; Faculté de pharmacie, Université de Montréal, Canada.; Laboratoire de suivi thérapeutique pharmacologique et pharmacocinétique, Faculté de pharmacie, Université de Montréal, Canada.

Subjects: Cystic Fibrosis*/Cystic Fibrosis*/Cystic Fibrosis*/drug therapy ; Tobramycin*; Adult

Source: British journal of clinical pharmacology [Br J Clin Pharmacol] 2022 May; Vol. 88 (5), pp. 2246-2255. Date of Electronic Publication: 2021 Dec 23.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Determination of tobramycin in eye drops with an open-source hardware ion mobility spectrometer.

Authors : Chantipmanee N; Department of Chemistry, University of Basel, Klingelbergstrasse 80, 4056, Basel, Switzerland.; Hauser PC

Subjects: Spectrometry, Mass, Electrospray Ionization* ; Tobramycin*; Calibration

Source: Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2022 Jun; Vol. 414 (14), pp. 4059-4066. Date of Electronic Publication: 2022 Apr 05.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 101134327 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The Xanthophyll Carotenoid Lutein Reduces the Invasive Potential of Pseudomonas aeruginosa and Increases Its Susceptibility to Tobramycin.

Authors : Mahavy CE; Laboratory of Biotechnology and Microbiology, University of Antananarivo, BP 906, Antananarivo 101, Madagascar.; Laboratory of Plant Biotechnology, Université Libre de Bruxelles, 6041 Gosselies, Belgium.

Subjects: Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/physiology ; Tobramycin*/Tobramycin*/Tobramycin*/pharmacology; Anti-Bacterial Agents/Anti-Bacterial Agents/Anti-Bacterial Agents/chemistry

Source: International journal of molecular sciences [Int J Mol Sci] 2022 Jun 28; Vol. 23 (13). Date of Electronic Publication: 2022 Jun 28.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

A Pharmacokinetic Analysis of Tobramycin in Patients Less than Five Years of Age with Cystic Fibrosis: Assessment of Target Attainment with Extended-Interval Dosing through Simulation.

Authors : Downes KJ; Division of Infectious, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Center for Clinical Pharmacology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

Subjects: Cystic Fibrosis*/Cystic Fibrosis*/Cystic Fibrosis*/drug therapy ; Tobramycin*/Tobramycin*/Tobramycin*/pharmacokinetics; Adolescent

Source: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2022 May 17; Vol. 66 (5), pp. e0237721. Date of Electronic Publication: 2022 Apr 28.Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Incorporating Fullerenes in Nanoscale Metal-Organic Matrixes: An Ultrasensitive Platform for Impedimetric Aptasensing of Tobramycin.

Authors : Zhang HW; Tianjin Key Laboratory of Structure and Performance for Functional Molecules, College of Chemistry, Tianjin Normal University, Tianjin 300387, China.; Li HK

Subjects: Aptamers, Nucleotide/Aptamers, Nucleotide/Aptamers, Nucleotide/*chemistry ; Biosensing Techniques/Biosensing Techniques/Biosensing Techniques/*methods ; Fullerenes/Fullerenes/Fullerenes/*chemistry

Source: ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2022 Feb 09; Vol. 14 (5), pp. 7350-7357. Date of Electronic Publication: 2022 Jan 25.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101504991 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Tobramycin and vestibulotoxicity: retrospective analysis of four cases.

Authors : Vonk SEM; Weersink EJM ...

Subjects: Cystic Fibrosis*/Cystic Fibrosis*/Cystic Fibrosis*/chemically induced ; Tobramycin*/Tobramycin*/Tobramycin*/adverse effects; Humans

Source: European journal of hospital pharmacy : science and practice [Eur J Hosp Pharm] 2022 Mar; Vol. 29 (e1), pp. e88-e90. Date of Electronic Publication: 2021 Mar 22.Publisher: BMJ Publishing Group Country of Publication: England NLM ID: 101578294 Publication Model: Print-Electronic Cited Medium: Print ISSN:

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Academic Journal

Risk Factors Associated with Suboptimal Tobramycin Levels in the Medical Intensive Care Unit.

Authors : Counts JP; Wexner Medical Center Department of Pharmacy, The Ohio State University, 410 W 10th Ave, Columbus, OH, 43210, USA.; Elefritz JL

Subjects: Intensive Care Units* ; Tobramycin*; Adolescent

Source: European journal of drug metabolism and pharmacokinetics [Eur J Drug Metab Pharmacokinet] 2022 Mar; Vol. 47 (2), pp. 271-278. Date of Electronic Publication: 2022 Jan 14.Publisher: Springer France Country of Publication: France NLM ID: 7608491 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Exploration of the Pharmacodynamics for Pseudomonas aeruginosa Biofilm Eradication by Tobramycin.

Authors : Sindeldecker D; Department of Microbial Infection and Immunity, The Ohio State Universitygrid.261331.4, Columbus, Ohio, USA.; Biomedical Sciences Graduate Program, The Ohio State Universitygrid.261331.4, Columbus, Ohio, USA.

Subjects: Pseudomonas Infections* ; Tobramycin*/Tobramycin*/Tobramycin*/pharmacology; Aminoglycosides

Source: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2022 Jan 18; Vol. 66 (1), pp. e0137121. Date of Electronic Publication: 2021 Oct 25.Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Rapid AMR prediction in Pseudomonas aeruginosa combining MALDI-TOF MS with DNN model.

Authors : Fu J; College of Medical Technology, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, P. R. China.; Chongqing Key Laboratory of Sichuan-Chongqing Co-construction for Diagnosis and Treatment of Infectious Diseases Integrated Traditional Chinese and Western Medicine, Chengdu 611137, P. R. China.

Subjects: Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/genetics ; Tobramycin*/Tobramycin*/Tobramycin*/pharmacology; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization/Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization/Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization/methods

Source: Journal of applied microbiology [J Appl Microbiol] 2023 Nov 01; Vol. 134 (11).Publisher: Oxford University Press Country of Publication: England NLM ID: 9706280 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Transferring Microclusters of P. aeruginosa Biofilms to the Air-Liquid Interface of Bronchial Epithelial Cells for Repeated Deposition of Aerosolized Tobramycin.

Authors : Horstmann JC; Department of Drug Delivery, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), 66123 Saarbrücken, Germany.; Department of Pharmacy, Saarland University, 66123 Saarbrücken, Germany.

Subjects: Pseudomonas aeruginosa* ; Tobramycin*/Tobramycin*/Tobramycin*/pharmacology; Anti-Bacterial Agents/Anti-Bacterial Agents/Anti-Bacterial Agents/pharmacology

Source: ACS infectious diseases [ACS Infect Dis] 2022 Jan 14; Vol. 8 (1), pp. 137-149. Date of Electronic Publication: 2021 Dec 17.Publisher: ACS Publications Country of Publication: United States NLM ID: 101654580 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Kidney Injury Monitoring in Tobramycin-Treated Rhesus Monkeys: Supplementing Urinary Kidney Biomarkers With Kidney Biopsy Gene Expression Profiling.

Authors : Gu YZ; Safety Assessment and Laboratory Animal Resources, 2793Merck & Co, Inc, West Point, PA, USA.; Handt L

Subjects: Acute Kidney Injury*/Acute Kidney Injury*/Acute Kidney Injury*/diagnosis ; Tobramycin*/Tobramycin*/Tobramycin*/metabolism; Animals

Source: Toxicologic pathology [Toxicol Pathol] 2022 Jan; Vol. 50 (1), pp. 35-46. Date of Electronic Publication: 2021 Oct 17.Publisher: Sage Publications Country of Publication: United States NLM ID: 7905907 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Tobramycin Supplemented Small-Diameter Vascular Grafts for Local Antibiotic Delivery: A Preliminary Formulation Study.

Authors : Rosalia M; Department of Drug Sciences, Pharmaceutical Section, University of Pavia, Via Taramelli 12, 27100 Pavia, Italy.; Ravipati P

Subjects: Blood Vessel Prosthesis* ; Drug Delivery Systems*/Drug Delivery Systems*/Drug Delivery Systems*/instrumentation; Anti-Bacterial Agents/Anti-Bacterial Agents/Anti-Bacterial Agents/*administration & dosage

Source: International journal of molecular sciences [Int J Mol Sci] 2021 Dec 17; Vol. 22 (24). Date of Electronic Publication: 2021 Dec 17.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Combined Treatment of 6-Gingerol Analog and Tobramycin for Inhibiting Pseudomonas aeruginosa Infections.

Authors : Ham SY; School of Civil, Environmental and Architectural Engineering, Korea Universitygrid.222754.4, Seoul, Republic of Korea.; Kim HS

Subjects: Anti-Bacterial Agents/Anti-Bacterial Agents/Anti-Bacterial Agents/*therapeutic use ; Catechols/Catechols/Catechols/*therapeutic use ; Fatty Alcohols/Fatty Alcohols/Fatty Alcohols/*therapeutic use

Source: Microbiology spectrum [Microbiol Spectr] 2021 Oct 31; Vol. 9 (2), pp. e0019221. Date of Electronic Publication: 2021 Oct 27.Publisher: ASM Press Country of Publication: United States NLM ID: 101634614 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Bayesian Forecasting for Intravenous Tobramycin Dosing in Adults With Cystic Fibrosis Using One Versus Two Serum Concentrations in a Dosing Interval.

Authors : Drennan PG; Department of Microbiology and Infectious Diseases, Royal Prince Alfred Hospital, Sydney, Australia.; Thoma Y

Subjects: Anti-Bacterial Agents*/Anti-Bacterial Agents*/Anti-Bacterial Agents*/administration & dosage ; Anti-Bacterial Agents*/Anti-Bacterial Agents*/Anti-Bacterial Agents*/pharmacokinetics ; Cystic Fibrosis*/Cystic Fibrosis*/Cystic Fibrosis*/drug therapy

Source: Therapeutic drug monitoring [Ther Drug Monit] 2021 Aug 01; Vol. 43 (4), pp. 505-511.Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 7909660 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Tobramycin and Colistin display anti-inflammatory properties in CuFi-1 cystic fibrosis cell line.

Authors : Sheikh Z; Respiratory Technology, The Woolcock Institute of Medical Research, Glebe, Australia; Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.

Subjects: Anti-Bacterial Agents/Anti-Bacterial Agents/Anti-Bacterial Agents/*pharmacology ; Anti-Inflammatory Agents, Non-Steroidal/Anti-Inflammatory Agents, Non-Steroidal/Anti-Inflammatory Agents, Non-Steroidal/*pharmacology ; Colistin/Colistin/Colistin/*pharmacology

Source: European journal of pharmacology [Eur J Pharmacol] 2021 Jul 05; Vol. 902, pp. 174098. Date of Electronic Publication: 2021 Apr 20.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Population Pharmacokinetic Modeling and Dosing Simulations of Tobramycin in Pediatric Patients with Cystic Fibrosis.

Authors : Praet A; Université Lyon, Université Lyon 1, UMR CNRS 5558, Laboratoire de Biométrie et Biologie Evolutive, Villeurbanne, France.; Université Lyon, Université Lyon 1, ISPB, Faculté de Pharmacie de Lyon, Lyon, France.

Subjects: Cystic Fibrosis*/Cystic Fibrosis*/Cystic Fibrosis*/drug therapy ; Tobramycin*; Anti-Bacterial Agents/Anti-Bacterial Agents/Anti-Bacterial Agents/therapeutic use

Source: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2021 Sep 17; Vol. 65 (10), pp. e0073721. Date of Electronic Publication: 2021 Jul 19.Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Effect of Local Delivery of Vancomycin and Tobramycin on Bone Regeneration.

Authors : Han W; Department of Traumatology, Beijing Jishuitan Hospital, Beijing, China.; Zhang L

Subjects: Bone Regeneration/Bone Regeneration/Bone Regeneration/*drug effects ; Mandible/Mandible/Mandible/*surgery ; Surgical Wound Infection/Surgical Wound Infection/Surgical Wound Infection/*prevention & control

Source: Orthopaedic surgery [Orthop Surg] 2021 Jul; Vol. 13 (5), pp. 1654-1661. Date of Electronic Publication: 2021 Jun 14.Publisher: Wiley on behalf of the Chinese Orthopedic Association Country of Publication: Australia NLM ID: 101501666 Publication Model: Print-Electronic

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Academic Journal

Using seconds-resolved pharmacokinetic datasets to assess pharmacokinetic models encompassing time-varying physiology.

Authors : McDonough MH; Department of Statistics and Applied Probability, University of California Santa Barbara, Santa Barbara, California, USA.; Stocker SL

Subjects: Tobramycin* ; Models, Biological*; Rats

Source: British journal of clinical pharmacology [Br J Clin Pharmacol] 2023 Sep; Vol. 89 (9), pp. 2798-2812. Date of Electronic Publication: 2023 May 23.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Pharmacodynamics of ceftazidime plus tobramycin combination dosage regimens against hypermutable Pseudomonas aeruginosa isolates at simulated epithelial lining fluid concentrations in a dynamic in vitro infection model.

Authors : Tait JR; Centre for Medicine Use and Safety, Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, VIC, Australia; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, VIC, Australia.

Subjects: Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/Pseudomonas aeruginosa*/genetics ; Tobramycin*/Tobramycin*/Tobramycin*/pharmacology; Anti-Bacterial Agents/Anti-Bacterial Agents/Anti-Bacterial Agents/pharmacology

Source: Journal of global antimicrobial resistance [J Glob Antimicrob Resist] 2021 Sep; Vol. 26, pp. 55-63. Date of Electronic Publication: 2021 May 21.Publisher: Published by Elsevier Ltd. on behalf of International Society of Chemotherapy for Infection and Cancer Country of Publication: Netherlands NLM ID:

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Academic Journal

Pharmacokinetic/pharmacodynamic evaluation of tobramycin dosing in critically ill patients: the Hartford nomogram does not fit.

Authors : Xie F; Division of Biopharmaceutics and Pharmacokinetics, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410013, China.; Wang Y

Subjects: Critical Illness* ; Tobramycin*; Anti-Bacterial Agents/Anti-Bacterial Agents/Anti-Bacterial Agents/therapeutic use

Source: The Journal of antimicrobial chemotherapy [J Antimicrob Chemother] 2021 Aug 12; Vol. 76 (9), pp. 2335-2341.Publisher: Oxford University Press Country of Publication: England NLM ID: 7513617 Publication Model: Print Cited Medium: Internet ISSN:

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A SnO 2 /Bi 2 S 3 -based photoelectrochemical aptasensor for sensitive detection of tobramycin in milk.

Authors : Liu X; College of Chemistry and Materials Science, Shanghai Normal University, Shanghai 200234, China.; Jiang Y

Subjects: Limit of Detection*; Aptamers, Nucleotide/Aptamers, Nucleotide/Aptamers, Nucleotide/*metabolism ; Biosensing Techniques/Biosensing Techniques/Biosensing Techniques/*methods

Source: Food chemistry [Food Chem] 2021 May 15; Vol. 344, pp. 128716. Date of Electronic Publication: 2020 Nov 25.Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 7702639 Publication Model: Print-Electronic Cited Medium:

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Combination of colistin and tobramycin inhibits persistence of Acinetobacter baumannii by membrane hyperpolarization and down-regulation of efflux pumps.

Authors : Kashyap S; Department of Biotechnology, Panjab University, Chandigarh, 160014, India.; Kaur S

Subjects: Acinetobacter baumannii/Acinetobacter baumannii/Acinetobacter baumannii/*drug effects ; Anti-Bacterial Agents/Anti-Bacterial Agents/Anti-Bacterial Agents/*pharmacology ; Colistin/Colistin/Colistin/*pharmacology Acinetobacter nosocomialis

Source: Microbes and infection [Microbes Infect] 2021 May-Jun; Vol. 23 (4-5), pp. 104795. Date of Electronic Publication: 2021 Feb 07.Publisher: Elsevier Country of Publication: France NLM ID: 100883508 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1769-714X

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Ototoxicity in cystic fibrosis patients receiving intravenous tobramycin for acute pulmonary exacerbation: Ototoxicity following tobramycin treatment.

Authors : Harruff EE; Sound Pharmaceuticals, Inc., 4010 Stone Way N, Ste 120, Seattle, WA, 98103, United States.; Kil J

Subjects: Ototoxicity*; Aminoglycosides/Aminoglycosides/Aminoglycosides/*adverse effects ; Cystic Fibrosis/Cystic Fibrosis/Cystic Fibrosis/*complications

Source: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society [J Cyst Fibros] 2021 Mar; Vol. 20 (2), pp. 288-294. Date of Electronic Publication: 2020 Dec Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101128966 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Comparative lung distribution of radiolabeled tobramycin between nebulized and intravenous administration in a mechanically-ventilated ovine model, an observational study.

Authors : Dhanani JA; UQ Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Brisbane, Australia; Department of Intensive Care Medicine, Royal Brisbane & Women's Hospital, Brisbane, Australia

Subjects: Respiration, Artificial*; Anti-Bacterial Agents/Anti-Bacterial Agents/Anti-Bacterial Agents/*administration & dosage ; Anti-Bacterial Agents/Anti-Bacterial Agents/Anti-Bacterial Agents/*pharmacokinetics

Source: International journal of antimicrobial agents [Int J Antimicrob Agents] 2021 Feb; Vol. 57 (2), pp. 106232. Date of Electronic Publication: 2020 Nov 21.Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 9111860 Publication Model: Print-Electronic Cited Medium: Internet

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Intraoperative Tobramycin Powder Prevents Enterobacter cloacae Surgical Site Infections in a Rabbit Model of Internal Fixation.

Authors : Brao K; Department of Microbial Pathogenesis, University of Maryland School of Dentistry, Baltimore, MD.; Department of Molecular Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD.

Subjects: Surgical Wound Infection*/Surgical Wound Infection*/Surgical Wound Infection*/drug therapy ; Surgical Wound Infection*/Surgical Wound Infection*/Surgical Wound Infection*/prevention & control ; Tobramycin*

Source: Journal of orthopaedic trauma [J Orthop Trauma] 2021 Jan 01; Vol. 35 (1), pp. 35-40.Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 8807705 Publication Model: Print Cited Medium: Internet ISSN:

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The Quorum-Sensing Inhibitor Furanone C-30 Rapidly Loses Its Tobramycin-Potentiating Activity against Pseudomonas aeruginosa Biofilms during Experimental Evolution.

Authors : Bové M; Laboratory of Pharmaceutical Microbiology, Ghent University, Ghent, Belgium.; Bao X

Source: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2021 Jun 17; Vol. 65 (7), pp. e0041321. Date of Electronic Publication: 2021 Jun 17.Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Print-Electronic Cited Medium:

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LC-MS/MS method for simultaneous quantification of dexamethasone and tobramycin in rabbit ocular biofluids.

Authors : Meng T; Department of Pharmaceutics, Virginia Commonwealth University, Richmond, VA 23298, USA.; Kosmider L

Subjects: Aqueous Humor/Aqueous Humor/Aqueous Humor/*chemistry ; Chromatography, Liquid/Chromatography, Liquid/Chromatography, Liquid/*methods ; Dexamethasone/Dexamethasone/Dexamethasone/*analysis

Source: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences [J Chromatogr B Analyt Technol Biomed Life Sci] 2021 Apr 30; Vol. 1170, pp. 122610. Date of Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101139554 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Prospective cohort study of ototoxicity in persons with cystic fibrosis following a single course of intravenous tobramycin.

Authors : Garinis A; Oregon Hearing Research Center (OHRC), Oregon Health & Science University (OHSU), Portland, OR, USA; VA RR&D National Center for Rehabilitative Auditory Research (NCRAR), VA Portland Health Care System, Portland, OR, USA. Electronic address: .

Subjects: Ototoxicity*; Aminoglycosides/Aminoglycosides/Aminoglycosides/*adverse effects ; Cystic Fibrosis/Cystic Fibrosis/Cystic Fibrosis/*complications

Source: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society [J Cyst Fibros] 2021 Mar; Vol. 20 (2), pp. 278-283. Date of Electronic Publication: 2020 Jul Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101128966 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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The effect of particle size of inhaled tobramycin dry powder on the eradication of Pseudomonas aeruginosa biofilms.

Authors : Aljalamdeh R; Department of Pharmacy and Pharmacology, University of Bath, Bath BA2 7AY, United Kingdom.; Price R

Subjects: Pseudomonas Infections* ; Tobramycin*/Tobramycin*/Tobramycin*/therapeutic use; Administration, Inhalation

Source: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2021 Mar 01; Vol. 158, pp. 105680. Date of Publisher: Elsevier Science B.V Country of Publication: Netherlands NLM ID: 9317982 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Development and validation of LC-MS/MS methods to measure tobramycin and lincomycin in plasma, microdialysis fluid and urine: application to a pilot pharmacokinetic research study.

Authors : Pandey S; UQ Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Brisbane, QLD 4029, Australia, Phone: +61 7 33465104.; Dhanani J

Subjects: Lincomycin/Lincomycin/Lincomycin/*analysis ; Tandem Mass Spectrometry/Tandem Mass Spectrometry/Tandem Mass Spectrometry/*methods ; Tobramycin/Tobramycin/Tobramycin/*analysis

Source: Clinical chemistry and laboratory medicine [Clin Chem Lab Med] 2020 Jan 28; Vol. 58 (2), pp. 274-284.Publisher: Walter De Gruyter Country of Publication: Germany NLM ID: 9806306 Publication Model: Print Cited Medium: Internet ISSN: 1437-4331

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