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Academic Journal

WNT1 Inducible Signaling Pathway Protein 1 Is a Stroma-Specific Secreting Protein Inducing a Fibroblast Contraction and Carcinoma Cell Growth in the Human Prostate.

  • Authors : Chang KS; Department of Anatomy, College of Medicine, Chang Gung University, Kwei-Shan, Taoyuan 33302, Taiwan.; Chen ST

Subjects: CCN Intercellular Signaling Proteins*/CCN Intercellular Signaling Proteins*/CCN Intercellular Signaling Proteins*/genetics ; CCN Intercellular Signaling Proteins*/CCN Intercellular Signaling Proteins*/CCN Intercellular Signaling Proteins*/metabolism ; Cell Transformation, Neoplastic*/Cell Transformation, Neoplastic*/Cell Transformation, Neoplastic*/genetics

  • Source: International journal of molecular sciences [Int J Mol Sci] 2022 Sep 28; Vol. 23 (19). Date of Electronic Publication: 2022 Sep 28.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

WNT1-inducible signalling pathway protein 1 stabilizes atherosclerotic plaques in apolipoprotein-E-deficient mice via the focal adhesion kinase/mitogen-activated extracellular signal-regulated kinase/extracellular signal-regulated kinase pathway.

  • Authors : Liu D; The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, The State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Department of Cardiology, Qilu Hospital of Shandong University, Jinan, China.; Zhang M

Subjects: CCN Intercellular Signaling Proteins*/CCN Intercellular Signaling Proteins*/CCN Intercellular Signaling Proteins*/genetics ; CCN Intercellular Signaling Proteins*/CCN Intercellular Signaling Proteins*/CCN Intercellular Signaling Proteins*/metabolism ; Focal Adhesion Kinase 1*/Focal Adhesion Kinase 1*/Focal Adhesion Kinase 1*/genetics

  • Source: Journal of hypertension [J Hypertens] 2022 Sep 01; Vol. 40 (9), pp. 1666-1681. Date of Electronic Publication: 2022 Jul 25.Publisher: Wolters Kluwer Health, Inc Country of Publication: Netherlands NLM ID: 8306882 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

WNT1-inducible signaling pathway protein 1 regulates kidney inflammation through the NF-κB pathway.

  • Authors : Wang B; Department of Kidney Transplantation, Nephropathy Hospital, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710061, P.R. China.; Department of Materials Science and Engineering, Monash University, Clayton, Victoria, Australia.

Subjects: Inflammation*; CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/*metabolism ; Diabetic Nephropathies/Diabetic Nephropathies/Diabetic Nephropathies/*etiology

  • Source: Clinical science (London, England : 1979) [Clin Sci (Lond)] 2022 Jan 14; Vol. 136 (1), pp. 29-44.Publisher: Portland Press on behalf of the Medical Research Society and the Biochemical Society Country of Publication: England NLM ID: 7905731 Publication Model:

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Academic Journal

Matricellular Protein WISP2 Is an Endogenous Inhibitor of Collagen Linearization and Cancer Metastasis.

  • Authors : Janjanam J; Comprehensive Cancer Center, Solid Tumor Program, Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee.; Pano G

Subjects: Gene Expression Regulation, Neoplastic*; Biomarkers, Tumor/Biomarkers, Tumor/Biomarkers, Tumor/*metabolism ; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*prevention & control

  • Source: Cancer research [Cancer Res] 2021 Nov 15; Vol. 81 (22), pp. 5666-5677. Date of Electronic Publication: 2021 Aug 12.Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium:

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Academic Journal

The small-secreted cysteine-rich protein CyrA is a virulence factor participating in the attack of Caenorhabditis elegans by Duddingtonia flagrans.

  • Authors : Wernet N; Karlsruhe Institute of Technology (KIT)-South Campus, Institute for Applied Biosciences, Dept. of Microbiology, Karlsruhe, Germany.; Wernet V

Subjects: Host-Pathogen Interactions*; CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/*metabolism ; Caenorhabditis elegans/Caenorhabditis elegans/Caenorhabditis elegans/*growth & development

  • Source: PLoS pathogens [PLoS Pathog] 2021 Nov 04; Vol. 17 (11), pp. e1010028. Date of Electronic Publication: 2021 Nov 04 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Dual roles of WISP2 in the progression of hepatocellular carcinoma: implications of the fibroblast infiltration into the tumor microenvironment.

  • Authors : Jia Q; Institute of Medical Research, Northwestern Polytechnical University, Xi'an 710072, China.; Zhang Y

Subjects: Tumor Microenvironment*; CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/*metabolism ; Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/*metabolism

  • Source: Aging [Aging (Albany NY)] 2021 Sep 08; Vol. 13 (17), pp. 21216-21231. Date of Electronic Publication: 2021 Sep 08.Publisher: Impact Journals, LLC Country of Publication: United States NLM ID: 101508617 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

WISP1 aggravates cell metastatic potential by abrogating TGF- β -Smad2/3-dependent epithelial-to-mesenchymal transition in laryngeal squamous cell carcinoma.

  • Authors : Song D; Department of Otolaryngology-Head and Neck Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, P.R. China.; Wang L

Subjects: CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/*metabolism ; Epithelial-Mesenchymal Transition/Epithelial-Mesenchymal Transition/Epithelial-Mesenchymal Transition/*physiology ; Laryngeal Neoplasms/Laryngeal Neoplasms/Laryngeal Neoplasms/*pathology

  • Source: Experimental biology and medicine (Maywood, N.J.) [Exp Biol Med (Maywood)] 2021 Jun; Vol. 246 (11), pp. 1244-1252. Date of Electronic Publication: 2021 Feb 16.Publisher: Sage Country of Publication: England NLM ID: 100973463 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-3699

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Academic Journal

Hepatic Wnt1 Inducible Signaling Pathway Protein 1 (WISP-1/CCN4) Associates with Markers of Liver Fibrosis in Severe Obesity.

  • Authors : Pivovarova-Ramich O; Research Group Molecular Nutritional Medicine, Department of Molecular Toxicology, German Institute of Human Nutrition Potsdam-Rehbruecke, 14558 Nuthetal, Germany.; Department of Clinical Nutrition, German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE), 14558 Nuthetal, Germany.

Subjects: CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/*metabolism ; Liver/Liver/Liver/*metabolism ; Liver Cirrhosis/Liver Cirrhosis/Liver Cirrhosis/*metabolism

  • Source: Cells [Cells] 2021 Apr 29; Vol. 10 (5). Date of Electronic Publication: 2021 Apr 29.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

WISP2/IGF1 promotes the survival of DSCs and impairs the cytotoxicity of decidual NK cells.

  • Authors : Shi JW; Laboratory for Reproductive Immunology, NHC Key Lab of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), Hospital of Obstetrics and Gynecology, Shanghai Medical School, Fudan University, Shanghai, People's Republic of China.; Laboratory for Reproductive Immunology, Institute of Obstetrics and Gynecology, Hospital of Obstetrics and Gynecology, Shanghai Medical School, Fudan University, Shanghai, People's Republic of China.

Subjects: Abortion, Habitual/Abortion, Habitual/Abortion, Habitual/*prevention & control ; CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/*metabolism ; Decidua/Decidua/Decidua/*cytology

  • Source: Reproduction (Cambridge, England) [Reproduction] 2021 Apr; Vol. 161 (4), pp. 425-436.Publisher: Published for the Society for Reproduction and Fertility by BioScientifica Country of Publication: England NLM ID: 100966036 Publication Model:

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Academic Journal

CCN5 activation by free or encapsulated EGCG is required to render triple-negative breast cancer cell viability and tumor progression.

  • Authors : Das A; Cancer Research Unit, VA Medical Center, Kansas City, MO, USA.; Haque I

Subjects: Nanoparticle Drug Delivery System*; CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/*agonists ; Catechin/Catechin/Catechin/*analogs & derivatives

  • Source: Pharmacology research & perspectives [Pharmacol Res Perspect] 2021 Apr; Vol. 9 (2), pp. e00753.Publisher: John Wiley & Sons Ltd, British Pharmacological Society and American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States

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Academic Journal

WISP1 Protects Against Chondrocyte Senescence and Apoptosis by Regulating αvβ3 and PI3K/Akt Pathway in Osteoarthritis.

  • Authors : Cheng C; Department of Orthopaedics, Yiyang Central Hospital, Yiyang, China.; Clinical Medical Technology Demonstration Base for Minimally Invasive and Digital Orthopaedics in Hunan Province, Yiyang, China.

Subjects: CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/*metabolism ; Chondrocytes/Chondrocytes/Chondrocytes/*metabolism ; Osteoarthritis, Knee/Osteoarthritis, Knee/Osteoarthritis, Knee/*metabolism

  • Source: DNA and cell biology [DNA Cell Biol] 2021 Apr; Vol. 40 (4), pp. 629-637. Date of Electronic Publication: 2021 Mar 01.Publisher: Mary Ann Liebert Country of Publication: United States NLM ID: 9004522 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Protective effect of estrogen receptors (ERα/β) against the intervertebral disc degeneration involves activating CCN5 via the promoter.

  • Authors : Song MX; Department of Orthopedics, Affiliated Hospital of Qingdao University, Qingdao, China. .; Ma XX

Subjects: CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/*metabolism ; Estrogen Receptor alpha/Estrogen Receptor alpha/Estrogen Receptor alpha/*metabolism ; Estrogen Receptor beta/Estrogen Receptor beta/Estrogen Receptor beta/*metabolism

  • Source: European review for medical and pharmacological sciences [Eur Rev Med Pharmacol Sci] 2021 Feb; Vol. 25 (4), pp. 1811-1820.Publisher: Verduci Country of Publication: Italy NLM ID: 9717360 Publication Model: Print Cited Medium: Internet ISSN: 2284-0729 (Electronic)

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Academic Journal

Diagnostic Value of the Hypomethylation of the WISP1 Promoter in Patients with Hepatocellular Carcinoma Associated with Hepatitis B Virus.

  • Authors : Chen LM; Department of Hepatology, Qilu Hospital of Shandong University.; Xiang L

Subjects: Promoter Regions, Genetic*; CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/*genetics ; Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/*diagnosis

  • Source: The Tohoku journal of experimental medicine [Tohoku J Exp Med] 2020 Dec; Vol. 252 (4), pp. 297-307.Publisher: Tohoku University Medical Library Country of Publication: Japan NLM ID: 0417355 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Wisp1 is a circulating factor that stimulates proliferation of adult mouse and human beta cells.

  • Authors : Fernandez-Ruiz R; August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Rosselló 149-153, 08036, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Barcelona, Spain.

Subjects: Aging/Aging/Aging/*physiology ; CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/*metabolism ; Insulin-Secreting Cells/Insulin-Secreting Cells/Insulin-Secreting Cells/*physiology

  • Source: Nature communications [Nat Commun] 2020 Nov 25; Vol. 11 (1), pp. 5982. Date of Electronic Publication: 2020 Nov 25.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

The Effects of microRNA-515-5p on the Toll-Like Receptor 4 (TLR4)/JNK Signaling Pathway and WNT1-Inducible-Signaling Pathway Protein 1 (WISP-1) Expression in Rheumatoid Arthritis Fibroblast-Like Synovial (RAFLS) Cells Following Treatment with Receptor Activator of Nuclear Factor-kappa-B Ligand (RANKL).

  • Authors : Cai D; Department of Joint Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China (mainland).; Hong S

Subjects: Arthritis, Rheumatoid/Arthritis, Rheumatoid/Arthritis, Rheumatoid/*metabolism ; CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/*genetics ; MAP Kinase Signaling System/MAP Kinase Signaling System/MAP Kinase Signaling System/*drug effects

  • Source: Medical science monitor : international medical journal of experimental and clinical research [Med Sci Monit] 2020 May 03; Vol. 26, pp. e920611. Date of Electronic Publication: Publisher: International Scientific Information, Inc Country of Publication: United States NLM ID: 9609063 Publication Model: Electronic Cited Medium:

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Academic Journal

Prospects and Perspectives for WISP1 (CCN4) in Diabetes Mellitus.

  • Authors : Maiese K; Cellular and Molecular Signaling, New York, NY 10022, United States.

Subjects: CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/*metabolism ; CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/*therapeutic use ; Diabetes Mellitus/Diabetes Mellitus/Diabetes Mellitus/*drug therapy

  • Source: Current neurovascular research [Curr Neurovasc Res] 2020; Vol. 17 (3), pp. 327-331.Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 101208439 Publication Model: Print Cited Medium: Internet

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Academic Journal

WNT1-inducible-signaling pathway protein 1 regulates the development of kidney fibrosis through the TGF-β1 pathway.

  • Authors : Wang B; Department of Kidney Transplantation, Nephropathy Hospital, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, P.R. China.; Department of Materials Science and Engineering, Monash University, Clayton, VIC, Australia.

Subjects: CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/*metabolism ; Diabetic Nephropathies/Diabetic Nephropathies/Diabetic Nephropathies/*metabolism ; Fibroblasts/Fibroblasts/Fibroblasts/*metabolism

  • Source: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2020 Nov; Vol. 34 (11), pp. 14507-14520. Date of Electronic Publication:Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print-Electronic

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Academic Journal

Polymorphisms of CSF1R and WISP1 genes are associated with severity of familial adenomatous polyposis in APC 1311 pigs.

  • Authors : Sikorska A; Department of Genetics and Animal Breeding, Poznan University of Life Sciences, Wolynska 33, 60-637 Poznan, Poland.; Stachowiak M

Subjects: Polymorphism, Single Nucleotide*; Adenomatous Polyposis Coli/Adenomatous Polyposis Coli/Adenomatous Polyposis Coli/*genetics ; Adenomatous Polyposis Coli Protein/Adenomatous Polyposis Coli Protein/Adenomatous Polyposis Coli Protein/*genetics

  • Source: Gene [Gene] 2020 Oct 30; Vol. 759, pp. 144988. Date of Electronic Publication: 2020 Jul 25.Publisher: Elsevier/North-Holland Country of Publication: Netherlands NLM ID: 7706761 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

High expression of WISP1 promotes metastasis and predicts poor prognosis in hepatocellular carcinoma.

  • Authors : Wang QY; Department of GI Medicine, Rizhao People's Hospital, Rizhao, China. .; Feng YJ

Subjects: CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/*genetics ; Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/*diagnosis ; Liver Neoplasms/Liver Neoplasms/Liver Neoplasms/*diagnosis

  • Source: European review for medical and pharmacological sciences [Eur Rev Med Pharmacol Sci] 2020 Oct; Vol. 24 (20), pp. 10445-10451.Publisher: Verduci Country of Publication: Italy NLM ID: 9717360 Publication Model: Print Cited Medium: Internet ISSN: 2284-0729 (Electronic)

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Academic Journal

CCN6 regulates mitochondrial respiratory complex assembly and activity.

  • Authors : Padhan DK; Cancer Biology and Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology, Kolkata, India.; Sengupta A

Subjects: CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/*metabolism ; Chondrocytes/Chondrocytes/Chondrocytes/*metabolism ; Mitochondria/Mitochondria/Mitochondria/*metabolism

  • Source: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2020 Sep; Vol. 34 (9), pp. 12163-12176. Date of Electronic Publication: Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print-Electronic

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Academic Journal

Mechanical stimulations can inhibit local and remote tumor progression by downregulating WISP1.

  • Authors : Liu S; Department of Biomedical Engineering, Indiana University Purdue University Indianapolis, Indianapolis, IN, USA.; Wu D

Subjects: Exercise Therapy* ; Physical Conditioning, Animal*; Bone Neoplasms/Bone Neoplasms/Bone Neoplasms/*therapy

  • Source: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2020 Sep; Vol. 34 (9), pp. 12847-12859. Date of Electronic Publication: Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print-Electronic

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Academic Journal

Dual Role of WISP1 in maintaining glioma stem cells and tumor-supportive macrophages in glioblastoma.

  • Authors : Tao W; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, 44195, USA.; Chu C

Subjects: Brain Neoplasms/Brain Neoplasms/Brain Neoplasms/*genetics ; CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/*genetics ; Glioma/Glioma/Glioma/*genetics

  • Source: Nature communications [Nat Commun] 2020 Jun 15; Vol. 11 (1), pp. 3015. Date of Electronic Publication: 2020 Jun 15.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Conjunction junction, what's the function? CCN proteins as targets in fibrosis and cancers.

  • Authors : Leask A; School of Dentistry, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.

Subjects: Cell Communication* ; Cellular Microenvironment* ; Signal Transduction*

  • Source: American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2020 Jun 01; Vol. 318 (6), pp. C1046-C1054. Date of Electronic Publication: 2020 Mar 04.Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901225 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

WISP-2, an upregulated gene in hip cartilage from the DDH model rats, induces chondrocyte apoptosis through PPARγ in vitro.

  • Authors : Ji X; Department of Hand and Foot Surgery, Shengjing Hospital of China Medical University, Shenyang, People's Republic of China.; Liu T

Subjects: Apoptosis*; CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/*metabolism ; Chondrocytes/Chondrocytes/Chondrocytes/*metabolism

  • Source: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2020 Apr; Vol. 34 (4), pp. 4904-4917. Date of Electronic Publication: Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print-Electronic

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Academic Journal

MiR-128-3p Post-Transcriptionally Inhibits WISP1 to Suppress Apoptosis and Inflammation in Human Articular Chondrocytes via the PI3K/AKT/NF-κB Signaling Pathway.

  • Authors : Chen S; Department of Orthopedics, Huaihe Hospital of Henan University, Kaifeng, China.; Li B

Subjects: CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/*antagonists & inhibitors ; Chondrocytes/Chondrocytes/Chondrocytes/*metabolism ; MicroRNAs/MicroRNAs/MicroRNAs/*metabolism

  • Source: Cell transplantation [Cell Transplant] 2020 Jan-Dec; Vol. 29, pp. 963689720939131.Publisher: SAGE Publishing Country of Publication: United States NLM ID: 9208854 Publication Model: Print Cited Medium: Internet ISSN: 1555-3892

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  • 25-50 of  1,042 results for ""CCN Intercellular Signaling Proteins""